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Murcko scaffold

Ring system with 5 rings and 15 atoms

23 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
15
Chemicals
23
With full pages
3
Scaffold SMILES

O=C1OC2CC1C1C3OC3C3(CO3)C1C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OC2CC1C1C3OC3C3(CO3)C1C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

Coriamyrtione chemical structure, C15H18O5
Coriamyrtione
C15H18O5
Tutin chemical structure, C15H18O6, CAS 2571-22-4
Tutin
CAS 2571-22-4C15H18O6
1b-Hydroxy-6a-methyl-3-oxo-8-(prop-1-en-2-yl)octahydrospiro[2,5-methanooxireno[3,4]cyclopenta[1,2-d]oxepine-7,2'-oxiran]-6-yl acetate chemical structure, C17H20O7
1b-Hydroxy-6a-methyl-3-oxo-8-(prop-1-en-2-yl)octahydrospiro[2,5-methanooxireno[3,4]cyclopenta[1,2-d]oxepine-7,2'-oxiran]-6-yl acetate
C17H20O7
2-Hydroxy-7-methyl-12-prop-1-en-2-ylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-11-one chemical structure, C15H18O5
2-Hydroxy-7-methyl-12-prop-1-en-2-ylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-11-one
C15H18O5
(1S,2R,3S,5R,6R,7R,9S,12R)-2-Hydroxy-7-methyl-12-prop-1-en-2-ylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-11-one chemical structure, C15H18O5
(1S,2R,3S,5R,6R,7R,9S,12R)-2-Hydroxy-7-methyl-12-prop-1-en-2-ylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-11-one
C15H18O5
Hyenanchin chemical structure, C15H18O7, CAS 3484-46-6
Hyenanchin
CAS 3484-46-6C15H18O7
2,8-Dihydroxy-12-(2-hydroxypropan-2-yl)-7-methylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-11-one chemical structure, C15H20O7
2,8-Dihydroxy-12-(2-hydroxypropan-2-yl)-7-methylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-11-one
C15H20O7
Npc147807 chemical structure, C15H18O5
Npc147807
C15H18O5
Isohyenanchin chemical structure, C15H20O7, CAS 19417-00-6
Isohyenanchin
CAS 19417-00-6C15H20O7
Coriatin chemical structure, C15H20O6, CAS 91653-75-7
Coriatin
CAS 91653-75-7C15H20O6
Coriaria lactone chemical structure, C15H18O6, CAS 79029-98-4
Coriaria lactone
CAS 79029-98-4C15H18O6
Tutin monoacetate chemical structure, C17H22O8, CAS 27556-19-0
Tutin monoacetate
CAS 27556-19-0C17H22O8
2-O-Acetyltutin chemical structure, C17H20O7, CAS 2749-28-2
2-O-Acetyltutin
CAS 2749-28-2C17H20O7
Coriamyrtin chemical structure, C15H18O5, CAS 2571-86-0
Coriamyrtin
CAS 2571-86-0C15H18O5
Tutin diacetate chemical structure, C19H22O8, CAS 21416-52-4
Tutin diacetate
CAS 21416-52-4C19H22O8
(1S,2R,3S,5R,6R,7R,8S,9S,12S)-2,8-Dihydroxy-12-(2-hydroxypropan-2-yl)-7-methylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-11-one chemical structure, C15H20O7
(1S,2R,3S,5R,6R,7R,8S,9S,12S)-2,8-Dihydroxy-12-(2-hydroxypropan-2-yl)-7-methylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-11-one
C15H20O7
[(1S,2R,3S,5R,6R,7R,8S,9S,12R)-2-Hydroxy-7-methyl-11-oxo-12-prop-1-en-2-ylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-8-yl] acetate chemical structure, C17H20O7
[(1S,2R,3S,5R,6R,7R,8S,9S,12R)-2-Hydroxy-7-methyl-11-oxo-12-prop-1-en-2-ylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-8-yl] acetate
C17H20O7
6-O-Acetylcoriatin chemical structure, C17H22O7, CAS 1432063-63-2
6-O-Acetylcoriatin
CAS 1432063-63-2C17H22O7
(2R,6R,7R)-2,8-Dihydroxy-12-(2-hydroxypropan-2-yl)-7-methylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-11-one chemical structure, C15H20O7
(2R,6R,7R)-2,8-Dihydroxy-12-(2-hydroxypropan-2-yl)-7-methylspiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-11-one
C15H20O7
(2R,3S,5R,6R,7R,8R)-2-Hydroxy-12-isopropenyl-7-methyl-11-oxospiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2\'-oxiran]-8-yl acetate chemical structure, C17H20O7
(2R,3S,5R,6R,7R,8R)-2-Hydroxy-12-isopropenyl-7-methyl-11-oxospiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2\'-oxiran]-8-yl acetate
C17H20O7
[(1R,2S,3R,5S,6S,7S,9S,12R)-12-(2-Hydroxypropan-2-yl)-7-methyl-11-oxospiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-2-yl] acetate chemical structure, C17H22O7
[(1R,2S,3R,5S,6S,7S,9S,12R)-12-(2-Hydroxypropan-2-yl)-7-methyl-11-oxospiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2'-oxirane]-2-yl] acetate
C17H22O7
Hydroxycoriatin chemical structure, C15H20O7
Hydroxycoriatin
C15H20O7
6-O-Acetylcoriatin chemical structure, C17H22O7
6-O-Acetylcoriatin
C17H22O7