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Murcko scaffold

Ring system with 2 rings and 14 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
12
With full pages
1
Scaffold SMILES

C(#Cc1ccccn1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(#Cc1ccccn1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

3-Methoxy-5-(2-pyridinylethynyl)pyridine chemical structure, C13H10N2O, CAS 524924-76-3
3-Methoxy-5-(2-pyridinylethynyl)pyridine
CAS 524924-76-3C13H10N2O
2-Methyl-6-(2-(pyridin-3-yl)ethynyl)pyridine chemical structure, C13H10N2, CAS 219912-46-6
2-Methyl-6-(2-(pyridin-3-yl)ethynyl)pyridine
CAS 219912-46-6C13H10N2
[3H]methoxy-PEPy chemical structure, C13H10N2O, CAS 524924-80-9
[3H]methoxy-PEPy
CAS 524924-80-9C13H10N2O
2-[(5-Methoxy-3-pyridinyl)ethynyl]-6-methylpyridine chemical structure, C14H12N2O, CAS 824389-37-9
2-[(5-Methoxy-3-pyridinyl)ethynyl]-6-methylpyridine
CAS 824389-37-9C14H12N2O
2-[2-(5-Bromopyridin-3-yl)ethynyl]-5-methylpyridine chemical structure, C13H9BrN2, CAS 872428-51-8
2-[2-(5-Bromopyridin-3-yl)ethynyl]-5-methylpyridine
CAS 872428-51-8C13H9BrN2
3-Methoxymethyl-5-pyridin-2-ylethynyl-pyridine chemical structure, C14H12N2O, CAS 524924-77-4
3-Methoxymethyl-5-pyridin-2-ylethynyl-pyridine
CAS 524924-77-4C14H12N2O
3-Pyridinemethanol,5-[(6-methyl-2-pyridinyl)ethynyl]- chemical structure, C14H12N2O, CAS 824389-39-1
3-Pyridinemethanol,5-[(6-methyl-2-pyridinyl)ethynyl]-
CAS 824389-39-1C14H12N2O
5-(Pyridin-2-ylethynyl)pyridin-3-ol chemical structure, C12H8N2O, CAS 524924-82-1
5-(Pyridin-2-ylethynyl)pyridin-3-ol
CAS 524924-82-1C12H8N2O
5-[2-(4-Amino-2-pyridinyl)ethynyl]-3-pyridinamine chemical structure, C12H10N4, CAS 1219632-43-5
5-[2-(4-Amino-2-pyridinyl)ethynyl]-3-pyridinamine
CAS 1219632-43-5C12H10N4
Methyl 2-[2-(3-pyridinyl)ethynyl]-4-pyridinecarboxylate chemical structure, C14H10N2O2, CAS 1244021-19-9
Methyl 2-[2-(3-pyridinyl)ethynyl]-4-pyridinecarboxylate
CAS 1244021-19-9C14H10N2O2
3-(2-Pyridylethynyl)pyridin-2-amine chemical structure, C12H9N3, CAS 1429088-02-7
3-(2-Pyridylethynyl)pyridin-2-amine
CAS 1429088-02-7C12H9N3
2-[2-(3-Pyridinyl)ethynyl]-4-pyridinemethanol chemical structure, C13H10N2O, CAS 2540649-66-7
2-[2-(3-Pyridinyl)ethynyl]-4-pyridinemethanol
CAS 2540649-66-7C13H10N2O