CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 11 atoms

40 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
40
With full pages
4
Scaffold SMILES

c1cc(-c2nncs2)ccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(-c2nncs2)ccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

Acetamide, N-(5-(4-pyridyl)-1,3,4-thiadiazol-2-yl)- chemical structure, C9H8N4OS, CAS 3652-14-0
Acetamide, N-(5-(4-pyridyl)-1,3,4-thiadiazol-2-yl)-
CAS 3652-14-0C9H8N4OS
2-Amino-5-(4-pyridyl)-1,3,4-thiadiazole chemical structure, C7H6N4S, CAS 2002-04-2
2-Amino-5-(4-pyridyl)-1,3,4-thiadiazole
CAS 2002-04-2C7H6N4S
4-[5-(Methylsulfanyl)-1,3,4-thiadiazol-2-yl]pyridine chemical structure, C8H7N3S2, CAS 89806-20-2
4-[5-(Methylsulfanyl)-1,3,4-thiadiazol-2-yl]pyridine
CAS 89806-20-2C8H7N3S2
4-[5-(Methanesulfonyl)-1,3,4-thiadiazol-2-yl]-1-oxo-1lambda~5~-pyridine chemical structure, C8H7N3O3S2, CAS 89806-04-2
4-[5-(Methanesulfonyl)-1,3,4-thiadiazol-2-yl]-1-oxo-1lambda~5~-pyridine
CAS 89806-04-2C8H7N3O3S2
2-Ethylamino-5-(4-pyridyl)-1,3,4-thiadiazole chemical structure, C9H10N4S, CAS 35314-23-9
2-Ethylamino-5-(4-pyridyl)-1,3,4-thiadiazole
CAS 35314-23-9C9H10N4S
N-(5-Pyridin-4-yl-1,3,4-thiadiazol-2-yl)butanamide chemical structure, C11H12N4OS, CAS 331818-81-6
N-(5-Pyridin-4-yl-1,3,4-thiadiazol-2-yl)butanamide
CAS 331818-81-6C11H12N4OS
N-Methyl-N-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)acetamide chemical structure, C10H10N4OS, CAS 603074-48-2
N-Methyl-N-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)acetamide
CAS 603074-48-2C10H10N4OS
Allyl-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-amine chemical structure, C10H10N4S, CAS 15814-15-0
Allyl-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-amine
CAS 15814-15-0C10H10N4S
Pyridine, 4-(2-amino-1,3,4-thiadiazol-5-yl)-, hydrochloride chemical structure, C7H7ClN4S, CAS 70145-80-1
Pyridine, 4-(2-amino-1,3,4-thiadiazol-5-yl)-, hydrochloride
CAS 70145-80-1C7H7ClN4S
N-Methyl-N-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)propionamide chemical structure, C11H12N4OS, CAS 603074-76-6
N-Methyl-N-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)propionamide
CAS 603074-76-6C11H12N4OS
Propyl-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-amine chemical structure, C10H12N4S, CAS 35314-25-1
Propyl-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-amine
CAS 35314-25-1C10H12N4S
4-[5-(Ethanesulfonyl)-1,3,4-thiadiazol-2-yl]-1-oxo-1lambda~5~-pyridine chemical structure, C9H9N3O3S2, CAS 89806-09-7
4-[5-(Ethanesulfonyl)-1,3,4-thiadiazol-2-yl]-1-oxo-1lambda~5~-pyridine
CAS 89806-09-7C9H9N3O3S2
1-Oxo-4-[5-(propane-1-sulfonyl)-1,3,4-thiadiazol-2-yl]-1lambda~5~-pyridine chemical structure, C10H11N3O3S2, CAS 89806-10-0
1-Oxo-4-[5-(propane-1-sulfonyl)-1,3,4-thiadiazol-2-yl]-1lambda~5~-pyridine
CAS 89806-10-0C10H11N3O3S2
4-[5-(Butane-1-sulfonyl)-1,3,4-thiadiazol-2-yl]-1-oxo-1lambda~5~-pyridine chemical structure, C11H13N3O3S2, CAS 89806-11-1
4-[5-(Butane-1-sulfonyl)-1,3,4-thiadiazol-2-yl]-1-oxo-1lambda~5~-pyridine
CAS 89806-11-1C11H13N3O3S2
4-(5-Ethoxy-1,3,4-thiadiazol-2-yl)-1-oxo-1lambda~5~-pyridine chemical structure, C9H9N3O2S, CAS 111854-29-6
4-(5-Ethoxy-1,3,4-thiadiazol-2-yl)-1-oxo-1lambda~5~-pyridine
CAS 111854-29-6C9H9N3O2S
5-(4-Pyridinyl)-1,3,4-thiadiazole-2-carboxylic acid chemical structure, C8H5N3O2S, CAS 216959-86-3
5-(4-Pyridinyl)-1,3,4-thiadiazole-2-carboxylic acid
CAS 216959-86-3C8H5N3O2S
3-{[5-(Pyridin-4-yl)-1,3,4-thiadiazol-2-yl]carbamoyl}propanoic acid chemical structure, C11H10N4O3S, CAS 1179399-95-1
3-{[5-(Pyridin-4-yl)-1,3,4-thiadiazol-2-yl]carbamoyl}propanoic acid
CAS 1179399-95-1C11H10N4O3S
4-(5-Bromo-1,3,4-thiadiazol-2-yl)pyridine chemical structure, C7H4BrN3S, CAS 16439-93-3
4-(5-Bromo-1,3,4-thiadiazol-2-yl)pyridine
CAS 16439-93-3C7H4BrN3S
2-Chloro-5-(pyridin-4-yl)-1,3,4-thiadiazole chemical structure, C7H4ClN3S, CAS 935252-65-6
2-Chloro-5-(pyridin-4-yl)-1,3,4-thiadiazole
CAS 935252-65-6C7H4ClN3S
5-(3-Fluoropyridin-4-yl)-1,3,4-thiadiazol-2-amine chemical structure, C7H5FN4S, CAS 1481170-90-4
5-(3-Fluoropyridin-4-yl)-1,3,4-thiadiazol-2-amine
CAS 1481170-90-4C7H5FN4S
2-(Chloromethyl)-5-(pyridin-4-yl)-1,3,4-thiadiazole chemical structure, C8H6ClN3S, CAS 1482678-80-7
2-(Chloromethyl)-5-(pyridin-4-yl)-1,3,4-thiadiazole
CAS 1482678-80-7C8H6ClN3S
[5-(3-Fluoropyridin-4-yl)-1,3,4-thiadiazol-2-yl]methanamine chemical structure, C8H7FN4S, CAS 1466227-72-4
[5-(3-Fluoropyridin-4-yl)-1,3,4-thiadiazol-2-yl]methanamine
CAS 1466227-72-4C8H7FN4S
2-Amino-5-(3-chloro-4-pyridyl)-1,3,4-thiadiazole chemical structure, C7H5ClN4S, CAS 1504147-20-9
2-Amino-5-(3-chloro-4-pyridyl)-1,3,4-thiadiazole
CAS 1504147-20-9C7H5ClN4S
5-(2-(Methylamino)pyridin-4-yl)-1,3,4-thiadiazol-2-amine chemical structure, C8H9N5S, CAS 1240521-58-7
5-(2-(Methylamino)pyridin-4-yl)-1,3,4-thiadiazol-2-amine
CAS 1240521-58-7C8H9N5S