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Murcko scaffold

2-Thioxo-2,3,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-4(1H)-one scaffold

30 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
30
With full pages
11
Scaffold SMILES

O=c1[nH]c(=S)[nH]c2sc3c(c12)CCCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Thioxo-2,3,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-4(1H)-one page
Murcko scaffold O=c1[nH]c(=S)[nH]c2sc3c(c12)CCCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

3-(2-Methyl-2-propenyl)-2-sulfanyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C14H16N2OS2, CAS 314041-96-8
3-(2-Methyl-2-propenyl)-2-sulfanyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
CAS 314041-96-8C14H16N2OS2
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-ethyl-2-thioxo- chemical structure, C12H14N2OS2, CAS 59898-66-7
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-ethyl-2-thioxo-
CAS 59898-66-7C12H14N2OS2
2-Thioxo-2,3,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-4(1H)-one chemical structure, C10H10N2OS2, CAS 38201-60-4
2-Thioxo-2,3,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-4(1H)-one
CAS 38201-60-4C10H10N2OS2
2,3,5,6,7,8-Hexahydro-3-methyl-2-thioxo(1)benzothieno(2,3-d)pyrimidin-4(1H)-one chemical structure, C11H12N2OS2, CAS 38201-61-5
2,3,5,6,7,8-Hexahydro-3-methyl-2-thioxo(1)benzothieno(2,3-d)pyrimidin-4(1H)-one
CAS 38201-61-5C11H12N2OS2
3-Prop-2-enyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one chemical structure, C13H14N2OS2, CAS 42062-91-9
3-Prop-2-enyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one
CAS 42062-91-9C13H14N2OS2
3-Amino-2-thioxo-2,3,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-4(1H)-one chemical structure, C10H11N3OS2, CAS 151094-90-5
3-Amino-2-thioxo-2,3,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-4(1H)-one
CAS 151094-90-5C10H11N3OS2
3-Octyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one chemical structure, C18H26N2OS2, CAS 380436-78-2
3-Octyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one
CAS 380436-78-2C18H26N2OS2
3-Propyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one chemical structure, C13H16N2OS2, CAS 126105-95-1
3-Propyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one
CAS 126105-95-1C13H16N2OS2
3-(2-Methylpropyl)-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one chemical structure, C14H18N2OS2, CAS 721908-18-5
3-(2-Methylpropyl)-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one
CAS 721908-18-5C14H18N2OS2
2-Mercapto-3-pentyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C15H20N2OS2, CAS 565171-27-9
2-Mercapto-3-pentyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
CAS 565171-27-9C15H20N2OS2
4-(2-Methoxyethyl)-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one chemical structure, C13H16N2O2S2, CAS 748777-74-4
4-(2-Methoxyethyl)-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one
CAS 748777-74-4C13H16N2O2S2
4-(3-Methoxypropyl)-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one chemical structure, C14H18N2O2S2, CAS 568555-38-4
4-(3-Methoxypropyl)-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one
CAS 568555-38-4C14H18N2O2S2
4-(3-Methylbutyl)-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one chemical structure, C15H20N2OS2, CAS 734544-87-7
4-(3-Methylbutyl)-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one
CAS 734544-87-7C15H20N2OS2
3-Allyl-2-mercapto-7-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C14H16N2OS2, CAS 307512-22-7
3-Allyl-2-mercapto-7-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
CAS 307512-22-7C14H16N2OS2
7-tert-Butyl-2-sulfanyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C14H18N2OS2, CAS 351005-93-1
7-tert-Butyl-2-sulfanyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
CAS 351005-93-1C14H18N2OS2
11-Methyl-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one chemical structure, C11H12N2OS2, CAS 372180-34-2
11-Methyl-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one
CAS 372180-34-2C11H12N2OS2
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3,7-dimethyl-2-thioxo- chemical structure, C12H14N2OS2, CAS 132627-72-6
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3,7-dimethyl-2-thioxo-
CAS 132627-72-6C12H14N2OS2
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-ethyl-7-methyl-2-thioxo- chemical structure, C13H16N2OS2, CAS 132605-26-6
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-ethyl-7-methyl-2-thioxo-
CAS 132605-26-6C13H16N2OS2
2,3,5,6,7,8-Hexahydro-3,5-dimethyl-2-thioxo(1)benzothieno(2,3-d)pyrimidin-4(1H)-one chemical structure, C12H14N2OS2, CAS 132605-20-0
2,3,5,6,7,8-Hexahydro-3,5-dimethyl-2-thioxo(1)benzothieno(2,3-d)pyrimidin-4(1H)-one
CAS 132605-20-0C12H14N2OS2
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3,6-dimethyl-2-thioxo- chemical structure, C12H14N2OS2, CAS 132605-21-1
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3,6-dimethyl-2-thioxo-
CAS 132605-21-1C12H14N2OS2
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-ethyl-6-methyl-2-thioxo- chemical structure, C13H16N2OS2, CAS 132605-25-5
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-ethyl-6-methyl-2-thioxo-
CAS 132605-25-5C13H16N2OS2
11-Methyl-4-(3-methylbutyl)-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one chemical structure, C16H22N2OS2, CAS 571919-27-2
11-Methyl-4-(3-methylbutyl)-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one
CAS 571919-27-2C16H22N2OS2
11-tert-Butyl-4-propyl-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one chemical structure, C17H24N2OS2, CAS 744241-98-3
11-tert-Butyl-4-propyl-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one
CAS 744241-98-3C17H24N2OS2
7-Methyl-3-octyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one chemical structure, C19H28N2OS2, CAS 519151-95-2
7-Methyl-3-octyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one
CAS 519151-95-2C19H28N2OS2