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Murcko scaffold

Alpha-morpholino-N-phenylsuccinimide scaffold

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
27
With full pages
14
Scaffold SMILES

O=C1CC(N2CCOCC2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Alpha-morpholino-N-phenylsuccinimide page
Murcko scaffold O=C1CC(N2CCOCC2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

1-(4-Iodophenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione chemical structure, C14H15IN2O3, CAS 306732-13-8
1-(4-Iodophenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione
CAS 306732-13-8C14H15IN2O3
Alpha-morpholino-N-phenylsuccinimide chemical structure, C14H16N2O3, CAS 53541-45-0
Alpha-morpholino-N-phenylsuccinimide
CAS 53541-45-0C14H16N2O3
1-(4-Chlorophenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione chemical structure, C14H15ClN2O3, CAS 116659-42-8
1-(4-Chlorophenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione
CAS 116659-42-8C14H15ClN2O3
1-(4-Methoxyphenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione chemical structure, C15H18N2O4, CAS 98708-23-7
1-(4-Methoxyphenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione
CAS 98708-23-7C15H18N2O4
1-(3,4-Dimethylphenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione chemical structure, C16H20N2O3, CAS 462088-77-3
1-(3,4-Dimethylphenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione
CAS 462088-77-3C16H20N2O3
1-(3-Methylphenyl)-3-morpholin-4-ylazolidine-2,5-dione chemical structure, C15H18N2O3, CAS 293765-96-5
1-(3-Methylphenyl)-3-morpholin-4-ylazolidine-2,5-dione
CAS 293765-96-5C15H18N2O3
1-(3-Chlorophenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione chemical structure, C14H15ClN2O3, CAS 95498-46-7
1-(3-Chlorophenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione
CAS 95498-46-7C14H15ClN2O3
1-(3,4-Dichlorophenyl)-3-morpholin-4-ylazolidine-2,5-dione chemical structure, C14H14Cl2N2O3, CAS 331966-13-3
1-(3,4-Dichlorophenyl)-3-morpholin-4-ylazolidine-2,5-dione
CAS 331966-13-3C14H14Cl2N2O3
4-(3-Morpholin-4-yl-2,5-dioxopyrrolidin-1-yl)benzoic acid chemical structure, C15H16N2O5, CAS 313378-77-7
4-(3-Morpholin-4-yl-2,5-dioxopyrrolidin-1-yl)benzoic acid
CAS 313378-77-7C15H16N2O5
3-Morpholin-4-yl-1-(4-propoxyphenyl)pyrrolidine-2,5-dione chemical structure, C17H22N2O4, CAS 98708-25-9
3-Morpholin-4-yl-1-(4-propoxyphenyl)pyrrolidine-2,5-dione
CAS 98708-25-9C17H22N2O4
1-(4-Fluorophenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione chemical structure, C14H15FN2O3, CAS 142014-07-1
1-(4-Fluorophenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione
CAS 142014-07-1C14H15FN2O3
1-(3-Methoxyphenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione chemical structure, C15H18N2O4, CAS 333398-39-3
1-(3-Methoxyphenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione
CAS 333398-39-3C15H18N2O4
1-(3,5-Dichlorophenyl)-3-(4-morpholinyl)pyrrolidine-2,5-dione chemical structure, C14H14Cl2N2O3, CAS 32809-12-4
1-(3,5-Dichlorophenyl)-3-(4-morpholinyl)pyrrolidine-2,5-dione
CAS 32809-12-4C14H14Cl2N2O3
1-(3-Bromophenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione chemical structure, C14H15BrN2O3, CAS 331966-46-2
1-(3-Bromophenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione
CAS 331966-46-2C14H15BrN2O3
1-(3-Ethoxyphenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione chemical structure, C16H20N2O4, CAS 313380-79-9
1-(3-Ethoxyphenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione
CAS 313380-79-9C16H20N2O4
Methyl 4-(3-morpholin-4-yl-2,5-dioxopyrrolidin-1-yl)benzoate chemical structure, C16H18N2O5, CAS 313380-93-7
Methyl 4-(3-morpholin-4-yl-2,5-dioxopyrrolidin-1-yl)benzoate
CAS 313380-93-7C16H18N2O5
1-(4-Butoxyphenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione chemical structure, C18H24N2O4, CAS 98708-26-0
1-(4-Butoxyphenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione
CAS 98708-26-0C18H24N2O4
Ethyl 4-(3-morpholin-4-yl-2,5-dioxopyrrolidin-1-yl)benzoate chemical structure, C17H20N2O5, CAS 330865-06-0
Ethyl 4-(3-morpholin-4-yl-2,5-dioxopyrrolidin-1-yl)benzoate
CAS 330865-06-0C17H20N2O5
1-(4-Methylphenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione chemical structure, C15H18N2O3, CAS 98708-22-6
1-(4-Methylphenyl)-3-(morpholin-4-yl)pyrrolidine-2,5-dione
CAS 98708-22-6C15H18N2O3
1-(3,5-Dimethoxyphenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione chemical structure, C16H20N2O5, CAS 406179-06-4
1-(3,5-Dimethoxyphenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione
CAS 406179-06-4C16H20N2O5
3-(2,6-Dimethylmorpholin-4-yl)-1-(4-ethoxyphenyl)pyrrolidine-2,5-dione chemical structure, C18H24N2O4, CAS 473703-92-3
3-(2,6-Dimethylmorpholin-4-yl)-1-(4-ethoxyphenyl)pyrrolidine-2,5-dione
CAS 473703-92-3C18H24N2O4
3-Morpholin-4-yl-1-(2-propoxyphenyl)pyrrolidine-2,5-dione chemical structure, C17H22N2O4, CAS 415688-93-6
3-Morpholin-4-yl-1-(2-propoxyphenyl)pyrrolidine-2,5-dione
CAS 415688-93-6C17H22N2O4
1-(2,4-Dimethylphenyl)-3-morpholin-4-ylazolidine-2,5-dione chemical structure, C16H20N2O3, CAS 727983-27-9
1-(2,4-Dimethylphenyl)-3-morpholin-4-ylazolidine-2,5-dione
CAS 727983-27-9C16H20N2O3
1-(4-Acetylphenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione chemical structure, C16H18N2O4, CAS 6043-60-3
1-(4-Acetylphenyl)-3-morpholin-4-ylpyrrolidine-2,5-dione
CAS 6043-60-3C16H18N2O4