Murcko scaffold
Ring system with 2 rings and 13 atoms
96 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 96
- With full pages
- 10
Scaffold SMILES
O=c1ccncn1-c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 96 chemicals
4(3H)-Pyrimidinone, 3-(2-fluorophenyl)-2-(methylthio)-
CAS 89069-19-2C11H9FN2OS
4(3H)-Pyrimidinone, 3-(2-chlorophenyl)-2-(methylthio)-
CAS 89069-22-7C11H9ClN2OS
4(3H)-Pyrimidinone, 2-(methylthio)-3-phenyl-
CAS 89069-18-1C11H10N2OS
4(3H)-Pyrimidinone, 3-(2-methylphenyl)-2-(methylthio)-
CAS 80306-55-4C12H12N2OS
4(3H)-Pyrimidinone, 3-(2-methoxyphenyl)-2-(methylthio)-
CAS 80306-56-5C12H12N2O2S
4(3H)-Pyrimidinone, 2-(methylthio)-3-(3-(trifluoromethyl)phenyl)-
CAS 89069-33-0C12H9F3N2OS
Benzoic acid, 2-chloro-4-fluoro-5-(2-methoxy-6-oxo-4-(pentafluoroethyl)-1(6H)-pyrimidinyl)-, 1-methyl ethyl ester
CAS 115784-92-4C17H13ClF6N2O4
4(3H)-Pyrimidinone, 2,6-dimethyl-3-(2-methylphenyl)-
CAS 2722-66-9C13H14N2O
6-Methyl-3-phenylpyrimidin-4(3H)-one
CAS 53399-18-1C11H10N2O
3-(4-Methylphenyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one
CAS 89069-26-1C12H12N2OS
3-(4-Methoxyphenyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one
CAS 89069-28-3C12H12N2O2S
3-(3-Methoxyphenyl)-2-(methylthio)pyrimidin-4(3H)-one
CAS 89069-27-2C12H12N2O2S
Ethyl 1-(4-methoxyphenyl)-2-methylsulfanyl-6-oxopyrimidine-5-carboxylate
CAS 82636-20-2C15H16N2O4S
Ethyl 1-(2,6-dichlorophenyl)-2-methylsulfanyl-6-oxo-pyrimidine-5-carboxylate
CAS 82636-21-3C14H12Cl2N2O3S
Ethyl 1-(4-chlorophenyl)-2-methylsulfanyl-6-oxopyrimidine-5-carboxylate
CAS 82636-15-5C14H13ClN2O3S
Ethyl 1-(5-chloro-2-methylphenyl)-2-methylsulfanyl-6-oxopyrimidine-5-carboxylate
CAS 82636-22-4C15H15ClN2O3S
Ethyl 1-(2-chloro-6-methylphenyl)-2-methylsulfanyl-6-oxopyrimidine-5-carboxylate
CAS 82636-23-5C15H15ClN2O3S
Ethyl 1-(2-fluorophenyl)-2-methylsulfanyl-6-oxopyrimidine-5-carboxylate
CAS 82636-12-2C14H13FN2O3S
Ethyl 1-(4-fluorophenyl)-2-methylsulfanyl-6-oxo-pyrimidine-5-carboxylate
CAS 82636-14-4C14H13FN2O3S
Ethyl 1-(2-methylphenyl)-2-methylsulfanyl-6-oxopyrimidine-5-carboxylate
CAS 82636-16-6C15H16N2O3S
Ethyl 1-(4-methylphenyl)-2-methylsulfanyl-6-oxopyrimidine-5-carboxylate
CAS 82636-17-7C15H16N2O3S
Ethyl 1-(3-fluorophenyl)-2-methylsulfanyl-6-oxopyrimidine-5-carboxylate
CAS 82636-13-3C14H13FN2O3S
![Ethyl 2-methylsulfanyl-6-oxo-1-[2-(trifluoromethyl)phenyl]pyrimidine-5-carboxylate chemical structure, C15H13F3N2O3S, CAS 82636-24-6](/s/CAKQYKBOYSCKHA-UHFFFAOYSA-N.svg)
Ethyl 2-methylsulfanyl-6-oxo-1-[2-(trifluoromethyl)phenyl]pyrimidine-5-carboxylate
CAS 82636-24-6C15H13F3N2O3S
N-(4-Methyl-6-oxo-1-phenyl-1,6-dihydropyrimidin-5-yl)acetamide
CAS 89966-49-4C13H13N3O2
- 4(3H)-Pyrimidinone, 3-(4-chlorophenyl)-2-methyl-87356-56-7C11H9ClN2O
- 4(3H)-Pyrimidinone, 2,6-dimethyl-3-phenyl-32363-53-4C12H12N2O
- 2-(Isopropylsulfanyl)-3-phenyl-6-(trifluoromethyl)-4(3H)-pyrimidinone685107-82-8C14H13F3N2OS
- 2-(Ethylsulfanyl)-3-phenyl-6-(trifluoromethyl)-4(3H)-pyrimidinone692287-34-6C13H11F3N2OS
- 2-{[6-Oxo-1-phenyl-4-(trifluoromethyl)-1,6-dihydro-2-pyrimidinyl]sulfanyl}acetic acid685109-28-8C13H9F3N2O3S
- 3-{[6-Oxo-1-phenyl-4-(trifluoromethyl)-1,6-dihydro-2-pyrimidinyl]sulfanyl}propanoic acid692287-41-5C14H11F3N2O3S
- 2-[(2-Oxopropyl)sulfanyl]-3-phenyl-6-(trifluoromethyl)-4(3H)-pyrimidinone866049-80-1C14H11F3N2O2S
- 5-Chloro-6-(2-hydroxyethylamino)-3-phenylpyrimidin-4-one701953-53-9C12H12ClN3O2
- 4(3H)-Pyrimidinone, 3-(2,6-dichlorophenyl)-2-(methylthio)-89069-29-4C11H8Cl2N2OS
- 4(3H)-Pyrimidinone, 3-(5-chloro-2-methylphenyl)-2-(methylthio)-89069-30-7C12H11ClN2OS
- 4(3H)-Pyrimidinone, 3-(2-chloro-5-(trifluoromethyl)phenyl)-2-(methylthio)-89069-34-1C12H8ClF3N2OS
- 4(3H)-Pyrimidinone, 3-(2-ethylphenyl)-2-(methylthio)-89069-36-3C13H14N2OS
- 4(3H)-Pyrimidinone, 5-(dimethylamino)-6-methyl-3-phenyl-, dihydrobromide53399-23-8C13H17Br2N3O
- 4(3H)-Pyrimidinone, 2-methyl-3-(2-methylphenyl)-80306-52-1C12H12N2O
- 4(3H)-Pyrimidinone, 3-(2-fluorophenyl)-2-methyl-87356-51-2C11H9FN2O
- 3-(4-Fluorophenyl)-2-methylpyrimidin-4(3H)-one87356-53-4C11H9FN2O
- 4(3H)-Pyrimidinone, 3-(2,6-dichlorophenyl)-2-methyl-87356-59-0C11H8Cl2N2O
- 5-Amino-6-methyl-3-phenylpyrimidin-4(3H)-one65765-92-6C11H11N3O
- 3-(3-Fluorophenyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one89069-20-5C11H9FN2OS
- 3-(4-Fluorophenyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one89069-21-6C11H9FN2OS
- 3-(3-Chlorophenyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one89069-23-8C11H9ClN2OS
- 3-(3-Bromophenyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one89069-24-9C11H9BrN2OS
- 3-(3-Methylphenyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one89069-25-0C12H12N2OS
- 3-(2-Chloro-6-methylphenyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one89069-31-8C12H11ClN2OS
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Same ring framework with different atoms or bond orders
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