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Murcko scaffold

Pyrazolopiperidine scaffold

84 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
84
With full pages
10
Scaffold SMILES

c1n[nH]c2c1NCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolopiperidine page
Murcko scaffold c1n[nH]c2c1NCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 84 chemicals

Pyrazolopiperidine chemical structure, C6H9N3, CAS 933705-52-3
Pyrazolopiperidine
CAS 933705-52-3C6H9N3
4,5,6,7-Tetrahydro-2H-pyrazolo[4,3-b]pyridine hydrochloride chemical structure, C6H10ClN3, CAS 1187830-47-2
4,5,6,7-Tetrahydro-2H-pyrazolo[4,3-b]pyridine hydrochloride
CAS 1187830-47-2C6H10ClN3
tert-Butyl 2H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-4-carboxylate chemical structure, C11H17N3O2, CAS 1393845-78-7
tert-Butyl 2H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-4-carboxylate
CAS 1393845-78-7C11H17N3O2
3-Iodo-1,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester chemical structure, C11H16IN3O2, CAS 1251014-79-5
3-Iodo-1,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester
CAS 1251014-79-5C11H16IN3O2
3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine hydrochloride chemical structure, C7H9ClF3N3, CAS 2444550-64-3
3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine hydrochloride
CAS 2444550-64-3C7H9ClF3N3
3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine chemical structure, C7H8F3N3, CAS 853784-41-5
3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine
CAS 853784-41-5C7H8F3N3
3-Methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine chemical structure, C7H11N3, CAS 1338247-52-1
3-Methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine
CAS 1338247-52-1C7H11N3
4-[(tert-Butoxy)carbonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-3-carboxylic acid chemical structure, C12H17N3O4, CAS 1279820-63-1
4-[(tert-Butoxy)carbonyl]-1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-3-carboxylic acid
CAS 1279820-63-1C12H17N3O4
1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine chemical structure, C7H11N3, CAS 1421312-06-2
1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine
CAS 1421312-06-2C7H11N3
1,3-Dimethyl-4,5,6,7-tetrahydropyrazolo[4,5-b]pyridine chemical structure, C8H13N3, CAS 1780851-69-5
1,3-Dimethyl-4,5,6,7-tetrahydropyrazolo[4,5-b]pyridine
CAS 1780851-69-5C8H13N3
1H,4H,5H,6H,7H-Pyrazolo[4,3-b]pyridin-3-amine chemical structure, C6H10N4, CAS 1783416-95-4
1H,4H,5H,6H,7H-Pyrazolo[4,3-b]pyridin-3-amine
CAS 1783416-95-4C6H10N4
(1H,4H,5H,6H,7H-Pyrazolo(4,3-b)pyridin-3-yl)methanol chemical structure, C7H11N3O, CAS 1784502-61-9
(1H,4H,5H,6H,7H-Pyrazolo(4,3-b)pyridin-3-yl)methanol
CAS 1784502-61-9C7H11N3O
1H,4H,5H,6H,7H-Pyrazolo[4,3-b]pyridine-3-carboxylic acid chemical structure, C7H9N3O2, CAS 1785611-07-5
1H,4H,5H,6H,7H-Pyrazolo[4,3-b]pyridine-3-carboxylic acid
CAS 1785611-07-5C7H9N3O2
Methyl 1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-3-carboxylate chemical structure, C8H11N3O2, CAS 1658466-87-5
Methyl 1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-3-carboxylate
CAS 1658466-87-5C8H11N3O2
3-Bromo-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine chemical structure, C6H8BrN3, CAS 1783465-99-5
3-Bromo-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine
CAS 1783465-99-5C6H8BrN3
2-Methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-b]pyridine chemical structure, C7H11N3, CAS 1421312-20-0
2-Methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-b]pyridine
CAS 1421312-20-0C7H11N3
tert-Butyl 1-methyl-6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate chemical structure, C12H19N3O2, CAS 1421311-98-9
tert-Butyl 1-methyl-6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate
CAS 1421311-98-9C12H19N3O2
tert-Butyl 2-methyl-6,7-dihydro-2H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate chemical structure, C12H19N3O2, CAS 1421312-00-6
tert-Butyl 2-methyl-6,7-dihydro-2H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate
CAS 1421312-00-6C12H19N3O2
4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-b]pyridine dihydrochloride chemical structure, C6H11Cl2N3, CAS 1951444-56-6
4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-b]pyridine dihydrochloride
CAS 1951444-56-6C6H11Cl2N3
1-Methyl-3-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[4,3-b]pyridine chemical structure, C8H10F3N3, CAS 1246554-87-9
1-Methyl-3-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[4,3-b]pyridine
CAS 1246554-87-9C8H10F3N3
4-Methylsulfonyl-1,5,6,7-tetrahydropyrazolo[4,5-b]pyridine chemical structure, C7H11N3O2S, CAS 1850205-38-7
4-Methylsulfonyl-1,5,6,7-tetrahydropyrazolo[4,5-b]pyridine
CAS 1850205-38-7C7H11N3O2S
Ethyl 1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-3-carboxylate chemical structure, C9H13N3O2, CAS 1279819-74-7
Ethyl 1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-3-carboxylate
CAS 1279819-74-7C9H13N3O2
4-Acetyl-1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-3-carboxylic acid chemical structure, C9H11N3O3, CAS 2091370-12-4
4-Acetyl-1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-3-carboxylic acid
CAS 2091370-12-4C9H11N3O3
1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine hydrochloride chemical structure, C7H12ClN3, CAS 2065250-16-8
1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine hydrochloride
CAS 2065250-16-8C7H12ClN3