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Murcko scaffold

Ring system with 4 rings and 25 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
13
With full pages
5
Scaffold SMILES

O=C(Cc1ccccc1)Nc1cccc(-c2ccc3nncn3n2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)Nc1cccc(-c2ccc3nncn3n2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-(4-Methoxyphenyl)-N-(3-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)acetamide chemical structure, C20H17N5O2, CAS 891113-09-0
2-(4-Methoxyphenyl)-N-(3-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)acetamide
CAS 891113-09-0C20H17N5O2
2-(4-Ethoxyphenyl)-N-(3-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)acetamide chemical structure, C21H19N5O2, CAS 894063-39-9
2-(4-Ethoxyphenyl)-N-(3-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)acetamide
CAS 894063-39-9C21H19N5O2
2-(3,4-Dimethoxyphenyl)-N-(3-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)acetamide chemical structure, C21H19N5O3, CAS 894063-71-9
2-(3,4-Dimethoxyphenyl)-N-(3-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)acetamide
CAS 894063-71-9C21H19N5O3
2-(4-Chlorophenyl)-N-(3-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)acetamide chemical structure, C19H14ClN5O, CAS 891113-73-8
2-(4-Chlorophenyl)-N-(3-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)acetamide
CAS 891113-73-8C19H14ClN5O
N-(3-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-(4-fluorophenyl)acetamide chemical structure, C19H14FN5O, CAS 891113-93-2
N-(3-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-(4-fluorophenyl)acetamide
CAS 891113-93-2C19H14FN5O
N-(3-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-(m-tolyl)acetamide chemical structure, C20H17N5O, CAS 894064-13-2
N-(3-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-(m-tolyl)acetamide
CAS 894064-13-2C20H17N5O
2-(4-Methoxyphenyl)-N-[3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide chemical structure, C21H19N5O2, CAS 891117-87-6
2-(4-Methoxyphenyl)-N-[3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide
CAS 891117-87-6C21H19N5O2
2-(4-Ethoxyphenyl)-N-(3-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)acetamide chemical structure, C22H21N5O2, CAS 891119-29-2
2-(4-Ethoxyphenyl)-N-(3-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)acetamide
CAS 891119-29-2C22H21N5O2
2-(3,4-Dimethoxyphenyl)-N-(3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)acetamide chemical structure, C22H21N5O3, CAS 891119-92-9
2-(3,4-Dimethoxyphenyl)-N-(3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)acetamide
CAS 891119-92-9C22H21N5O3
N-(3-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-phenylbutanamide chemical structure, C22H21N5O, CAS 894053-26-0
N-(3-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-phenylbutanamide
CAS 894053-26-0C22H21N5O
2-(2-Chlorophenyl)-N-(3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)acetamide chemical structure, C20H16ClN5O, CAS 1058253-72-7
2-(2-Chlorophenyl)-N-(3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)acetamide
CAS 1058253-72-7C20H16ClN5O
N-(3-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-(2-chloro-6-fluorophenyl)acetamide chemical structure, C19H13ClFN5O, CAS 1058482-70-4
N-(3-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-(2-chloro-6-fluorophenyl)acetamide
CAS 1058482-70-4C19H13ClFN5O
N-(3-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-(2-methoxyphenyl)acetamide chemical structure, C20H17N5O2, CAS 1058482-71-5
N-(3-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-(2-methoxyphenyl)acetamide
CAS 1058482-71-5C20H17N5O2