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Murcko scaffold

Ring system with 3 rings and 19 atoms

26 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
26
With full pages
8
Scaffold SMILES

O=S(=O)(c1cccc2ccccc12)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1cccc2ccccc12)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

1-(4-Chloronaphthalen-1-yl)sulfonyl-4-methylpiperazine chemical structure, C15H17ClN2O2S, CAS 325812-53-1
1-(4-Chloronaphthalen-1-yl)sulfonyl-4-methylpiperazine
CAS 325812-53-1C15H17ClN2O2S
1-(4-Ethoxynaphthalen-1-yl)sulfonyl-4-methylpiperazine chemical structure, C17H22N2O3S, CAS 420806-86-6
1-(4-Ethoxynaphthalen-1-yl)sulfonyl-4-methylpiperazine
CAS 420806-86-6C17H22N2O3S
1-(4-Methoxynaphthalen-1-yl)sulfonyl-4-methylpiperazine chemical structure, C16H20N2O3S, CAS 457960-35-9
1-(4-Methoxynaphthalen-1-yl)sulfonyl-4-methylpiperazine
CAS 457960-35-9C16H20N2O3S
1-Ethyl-4-(4-methoxynaphthalen-1-yl)sulfonylpiperazine chemical structure, C17H22N2O3S, CAS 708244-27-3
1-Ethyl-4-(4-methoxynaphthalen-1-yl)sulfonylpiperazine
CAS 708244-27-3C17H22N2O3S
1-[(4-Ethoxynaphthalen-1-yl)sulfonyl]-4-ethylpiperazine chemical structure, C18H24N2O3S, CAS 701289-78-3
1-[(4-Ethoxynaphthalen-1-yl)sulfonyl]-4-ethylpiperazine
CAS 701289-78-3C18H24N2O3S
Ethyl 4-[(4-methoxy-1-naphthyl)sulfonyl]-1-piperazinecarboxylate chemical structure, C18H22N2O5S, CAS 694466-29-0
Ethyl 4-[(4-methoxy-1-naphthyl)sulfonyl]-1-piperazinecarboxylate
CAS 694466-29-0C18H22N2O5S
1-((4-Bromonaphthalen-1-yl)sulfonyl)-4-methylpiperazine chemical structure, C15H17BrN2O2S, CAS 312525-99-8
1-((4-Bromonaphthalen-1-yl)sulfonyl)-4-methylpiperazine
CAS 312525-99-8C15H17BrN2O2S
Ethyl 4-[(4-ethoxy-1-naphthyl)sulfonyl]piperazine-1-carboxylate chemical structure, C19H24N2O5S, CAS 681852-56-2
Ethyl 4-[(4-ethoxy-1-naphthyl)sulfonyl]piperazine-1-carboxylate
CAS 681852-56-2C19H24N2O5S
1-Acetyl-4-(naphthylsulfonyl)piperazine chemical structure, C16H18N2O3S, CAS 911643-04-4
1-Acetyl-4-(naphthylsulfonyl)piperazine
CAS 911643-04-4C16H18N2O3S
1-Dansylpiperazine chemical structure, C16H21N3O2S, CAS 86516-36-1
1-Dansylpiperazine
CAS 86516-36-1C16H21N3O2S
4-(2-Hydroxyethyl)-1-[(4-propoxynaphthyl)sulfonyl]piperazine chemical structure, C19H26N2O4S, CAS 941002-84-2
4-(2-Hydroxyethyl)-1-[(4-propoxynaphthyl)sulfonyl]piperazine
CAS 941002-84-2C19H26N2O4S
2-(4-((4-Ethoxynaphthalen-1-yl)sulfonyl)piperazin-1-yl)ethanol chemical structure, C18H24N2O4S, CAS 941256-77-5
2-(4-((4-Ethoxynaphthalen-1-yl)sulfonyl)piperazin-1-yl)ethanol
CAS 941256-77-5C18H24N2O4S
2-(4-((4-Methoxynaphthalen-1-yl)sulfonyl)piperazin-1-yl)ethanol chemical structure, C17H22N2O4S, CAS 941002-88-6
2-(4-((4-Methoxynaphthalen-1-yl)sulfonyl)piperazin-1-yl)ethanol
CAS 941002-88-6C17H22N2O4S
1-Methyl-4-{[4-(pentyloxy)naphthalen-1-yl]sulfonyl}piperazine chemical structure, C20H28N2O3S, CAS 941004-32-6
1-Methyl-4-{[4-(pentyloxy)naphthalen-1-yl]sulfonyl}piperazine
CAS 941004-32-6C20H28N2O3S
1-Acetyl-4-[(4-pentyloxynaphthyl)sulfonyl]piperazine chemical structure, C21H28N2O4S, CAS 941263-92-9
1-Acetyl-4-[(4-pentyloxynaphthyl)sulfonyl]piperazine
CAS 941263-92-9C21H28N2O4S
1-Acetyl-4-[(4-propoxynaphthyl)sulfonyl]piperazine chemical structure, C19H24N2O4S, CAS 941264-00-2
1-Acetyl-4-[(4-propoxynaphthyl)sulfonyl]piperazine
CAS 941264-00-2C19H24N2O4S
1-Acetyl-4-[(4-ethoxynaphthyl)sulfonyl]piperazine chemical structure, C18H22N2O4S, CAS 941008-51-1
1-Acetyl-4-[(4-ethoxynaphthyl)sulfonyl]piperazine
CAS 941008-51-1C18H22N2O4S
1-Acetyl-4-[(4-methoxynaphthyl)sulfonyl]piperazine chemical structure, C17H20N2O4S, CAS 941264-04-6
1-Acetyl-4-[(4-methoxynaphthyl)sulfonyl]piperazine
CAS 941264-04-6C17H20N2O4S
1-[(4-Butoxynaphthyl)sulfonyl]-4-methylpiperazine chemical structure, C19H26N2O3S, CAS 1087640-73-0
1-[(4-Butoxynaphthyl)sulfonyl]-4-methylpiperazine
CAS 1087640-73-0C19H26N2O3S
TG2-IN-3h chemical structure, C21H26N4O4S, CAS 1592640-75-9
TG2-IN-3h
CAS 1592640-75-9C21H26N4O4S
(4-((4-(tert-Butoxycarbonyl)piperazin-1-yl)sulfonyl)naphthalen-1-yl)boronic acid chemical structure, C19H25BN2O6S, CAS 1704120-96-6
(4-((4-(tert-Butoxycarbonyl)piperazin-1-yl)sulfonyl)naphthalen-1-yl)boronic acid
CAS 1704120-96-6C19H25BN2O6S
tert-Butyl 4-((4-bromonaphthalen-1-yl)sulfonyl)piperazine-1-carboxylate chemical structure, C19H23BrN2O4S, CAS 1704121-02-7
tert-Butyl 4-((4-bromonaphthalen-1-yl)sulfonyl)piperazine-1-carboxylate
CAS 1704121-02-7C19H23BrN2O4S
1-((4-Bromonaphthalen-1-yl)sulfonyl)-4-ethylpiperazine chemical structure, C16H19BrN2O2S, CAS 1704121-09-4
1-((4-Bromonaphthalen-1-yl)sulfonyl)-4-ethylpiperazine
CAS 1704121-09-4C16H19BrN2O2S
(4-((4-Ethylpiperazin-1-yl)sulfonyl)naphthalen-1-yl)boronic acid chemical structure, C16H21BN2O4S, CAS 1704121-11-8
(4-((4-Ethylpiperazin-1-yl)sulfonyl)naphthalen-1-yl)boronic acid
CAS 1704121-11-8C16H21BN2O4S