Murcko scaffold
Ring system with 5 rings and 30 atoms
5 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 30
- Chemicals
- 5
- With full pages
- 1
Scaffold SMILES
c1cc(CCN2CCC(CCc3ccc4c(n3)NCCC4)C2)cc(-n2cccn2)c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 5 of 5 chemicals
Gsk3008348 free base
CAS 1629249-33-7C29H37N5O2
Gsk-3008348
CAS 2365406-14-8C29H38ClN5O2
Integrin Antagonist 1 hydrochloride
CAS 1629249-40-6C29H38ClN5O2
Orb691977
C29H37N5O2
![(3R)-3-[3-(3,5-Dimethylpyrazol-1-yl)phenyl]-4-[(3S)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid, hydrochloride chemical structure, C29H38ClN5O2](/s/GCZLVFRSWWTRPH-YSCHMLPRSA-N.svg)
(3R)-3-[3-(3,5-Dimethylpyrazol-1-yl)phenyl]-4-[(3S)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]butanoic acid, hydrochloride
C29H38ClN5O2