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Murcko scaffold

4-Phenyl-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one scaffold

8 chemicals on CompoundList share this ring system.

Rings
6
Scaffold atoms
29
Chemicals
8
With full pages
3
Scaffold SMILES

O=c1c2c(n3cnnc3n1-c1ccccc1)-c1ccccc1CC21CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one page
Murcko scaffold O=c1c2c(n3cnnc3n1-c1ccccc1)-c1ccccc1CC21CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

4-Phenyl-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one chemical structure, C24H22N4O, CAS 294875-11-9
4-Phenyl-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one
CAS 294875-11-9C24H22N4O
4-(4-Methylphenyl)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one chemical structure, C25H24N4O, CAS 287491-57-0
4-(4-Methylphenyl)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one
CAS 287491-57-0C25H24N4O
4-(2-Methylphenyl)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one chemical structure, C25H24N4O, CAS 373377-19-6
4-(2-Methylphenyl)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one
CAS 373377-19-6C25H24N4O
1-(Isopentylsulfanyl)-4-(2-methylphenyl)-6,7-dihydrospiro(benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexane)-5(4H)-one chemical structure, C30H34N4OS, CAS 372502-27-7
1-(Isopentylsulfanyl)-4-(2-methylphenyl)-6,7-dihydrospiro(benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexane)-5(4H)-one
CAS 372502-27-7C30H34N4OS
4-(4-Methoxyphenyl)-1-(methylthio)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one chemical structure, C26H26N4O2S, CAS 373369-48-3
4-(4-Methoxyphenyl)-1-(methylthio)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one
CAS 373369-48-3C26H26N4O2S
1-(Allylthio)-4-(m-tolyl)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one chemical structure, C28H28N4OS, CAS 374104-53-7
1-(Allylthio)-4-(m-tolyl)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one
CAS 374104-53-7C28H28N4OS
1-(Prop-2-yn-1-ylthio)-4-(o-tolyl)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one chemical structure, C28H26N4OS, CAS 374550-16-0
1-(Prop-2-yn-1-ylthio)-4-(o-tolyl)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one
CAS 374550-16-0C28H26N4OS
4-(3-Methoxyphenyl)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one chemical structure, C25H24N4O2, CAS 380583-81-3
4-(3-Methoxyphenyl)-4H-spiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexan]-5(7H)-one
CAS 380583-81-3C25H24N4O2