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Murcko scaffold

Ring system with 4 rings and 28 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
11
With full pages
3
Scaffold SMILES

C(=C(c1ccccc1)c1ccc(OCCN2CCCC2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=C(c1ccccc1)c1ccc(OCCN2CCCC2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Pyrrolidine, 1-(2-(4-(1-(4-methoxyphenyl)-2-nitro-2-phenylethenyl)phenoxy)ethyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) chemical structure, C33H36N2O11, CAS 5863-35-4
Pyrrolidine, 1-(2-(4-(1-(4-methoxyphenyl)-2-nitro-2-phenylethenyl)phenoxy)ethyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
CAS 5863-35-4C33H36N2O11
Nitromifene chemical structure, C27H28N2O4, CAS 10448-84-7
Nitromifene
CAS 10448-84-7C27H28N2O4
1-[2-[4-[(Z)-1-(4-Methoxyphenyl)-2-nitro-2-phenylethenyl]phenoxy]ethyl]pyrrolidine chemical structure, C27H28N2O4, CAS 52235-18-4
1-[2-[4-[(Z)-1-(4-Methoxyphenyl)-2-nitro-2-phenylethenyl]phenoxy]ethyl]pyrrolidine
CAS 52235-18-4C27H28N2O4
Idoxifene chemical structure, C28H30INO, CAS 116057-75-1
Idoxifene
CAS 116057-75-1C28H30INO
CI 628M chemical structure, C26H26N2O4, CAS 76313-96-7
CI 628M
CAS 76313-96-7C26H26N2O4
1-(2-(p-(1,2-Bis(p-methoxyphenyl)-3-methyl-1-butenyl)phenoxy)ethyl)pyrrolidine hydrochloride chemical structure, C31H38ClNO3, CAS 42824-37-3
1-(2-(p-(1,2-Bis(p-methoxyphenyl)-3-methyl-1-butenyl)phenoxy)ethyl)pyrrolidine hydrochloride
CAS 42824-37-3C31H38ClNO3
trans-1-(2-(p-(1,2-Bis(p-methoxyphenyl)-1-butenyl)phenoxy)ethyl)pyrrolidine hydrochloride chemical structure, C30H36ClNO3, CAS 35278-53-6
trans-1-(2-(p-(1,2-Bis(p-methoxyphenyl)-1-butenyl)phenoxy)ethyl)pyrrolidine hydrochloride
CAS 35278-53-6C30H36ClNO3
1-(2-(4-(1,2-Bis(4-methoxyphenyl)-1-butenyl)phenoxy)ethyl)pyrrolidine chemical structure, C30H35NO3, CAS 35386-89-1
1-(2-(4-(1,2-Bis(4-methoxyphenyl)-1-butenyl)phenoxy)ethyl)pyrrolidine
CAS 35386-89-1C30H35NO3
1-(2-{4-[(1Z)-1-(4-Fluorophenyl)-2-phenyl-1-propenyl]phenoxy}ethyl)pyrrolidine 2-hydroxy-1,2,3-propanetricarboxylate chemical structure, C33H36FNO8, CAS 13554-26-2
1-(2-{4-[(1Z)-1-(4-Fluorophenyl)-2-phenyl-1-propenyl]phenoxy}ethyl)pyrrolidine 2-hydroxy-1,2,3-propanetricarboxylate
CAS 13554-26-2C33H36FNO8
1-[2-[4-[(Z)-1-(4-Iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine chemical structure, C28H30INO, CAS 129983-70-6
1-[2-[4-[(Z)-1-(4-Iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine
CAS 129983-70-6C28H30INO
1-[2-[4-[1-(4-Methoxyphenyl)-2-phenylethenyl]phenoxy]ethyl]-pyrrolidine chemical structure, C27H29NO2, CAS 13542-64-8
1-[2-[4-[1-(4-Methoxyphenyl)-2-phenylethenyl]phenoxy]ethyl]-pyrrolidine
CAS 13542-64-8C27H29NO2