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Murcko scaffold

Ring system with 3 rings and 20 atoms

26 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
26
With full pages
13
Scaffold SMILES

O=C(Nc1ccccc1N1CCNCC1)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1N1CCNCC1)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

N-[2-(4-Methylsulfonylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C16H19N3O4S, CAS 723753-68-2
N-[2-(4-Methylsulfonylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 723753-68-2C16H19N3O4S
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C17H20ClN3O2, CAS 714213-98-6
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 714213-98-6C17H20ClN3O2
5-Bromo-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C16H18BrN3O4S, CAS 712284-64-5
5-Bromo-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 712284-64-5C16H18BrN3O4S
5-Bromo-N-[3-chloro-2-(4-ethyl-1-piperazinyl)phenyl]-2-furamide chemical structure, C17H19BrClN3O2, CAS 712284-61-2
5-Bromo-N-[3-chloro-2-(4-ethyl-1-piperazinyl)phenyl]-2-furamide
CAS 712284-61-2C17H19BrClN3O2
N-[2-[4-(2-Methylpropanoyl)piperazin-1-yl]phenyl]-5-nitrofuran-2-carboxamide chemical structure, C19H22N4O5, CAS 708292-89-1
N-[2-[4-(2-Methylpropanoyl)piperazin-1-yl]phenyl]-5-nitrofuran-2-carboxamide
CAS 708292-89-1C19H22N4O5
N-[5-Chloro-2-(4-propanoylpiperazin-1-yl)phenyl]-5-nitrofuran-2-carboxamide chemical structure, C18H19ClN4O5, CAS 718601-71-9
N-[5-Chloro-2-(4-propanoylpiperazin-1-yl)phenyl]-5-nitrofuran-2-carboxamide
CAS 718601-71-9C18H19ClN4O5
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-5-nitrofuran-2-carboxamide chemical structure, C17H19ClN4O4, CAS 712290-41-0
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-5-nitrofuran-2-carboxamide
CAS 712290-41-0C17H19ClN4O4
N-[2-(4-Methylsulfonylpiperazin-1-yl)phenyl]-5-nitrofuran-2-carboxamide chemical structure, C16H18N4O6S, CAS 712290-43-2
N-[2-(4-Methylsulfonylpiperazin-1-yl)phenyl]-5-nitrofuran-2-carboxamide
CAS 712290-43-2C16H18N4O6S
N-[2-(4-Methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide chemical structure, C17H18F3N3O2, CAS 866134-08-9
N-[2-(4-Methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
CAS 866134-08-9C17H18F3N3O2
5-Bromo-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide chemical structure, C19H22BrN3O3, CAS 761418-32-0
5-Bromo-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide
CAS 761418-32-0C19H22BrN3O3
N-(2-(4-Methylpiperazin-1-yl)phenyl)-5-nitrofuran-2-carboxamide chemical structure, C16H18N4O4, CAS 713500-92-6
N-(2-(4-Methylpiperazin-1-yl)phenyl)-5-nitrofuran-2-carboxamide
CAS 713500-92-6C16H18N4O4
N-[5-Chloro-2-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C18H20ClN3O3, CAS 717833-79-9
N-[5-Chloro-2-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 717833-79-9C18H20ClN3O3
Methyl 3-[(5-bromofuran-2-carbonyl)amino]-4-(4-methylpiperazin-1-yl)benzoate chemical structure, C18H20BrN3O4, CAS 847239-54-7
Methyl 3-[(5-bromofuran-2-carbonyl)amino]-4-(4-methylpiperazin-1-yl)benzoate
CAS 847239-54-7C18H20BrN3O4
N-[2-(4-Acetylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C17H19N3O3, CAS 842114-72-1
N-[2-(4-Acetylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 842114-72-1C17H19N3O3
Methyl 4-(4-acetylpiperazin-1-yl)-3-[(5-bromofuran-2-carbonyl)amino]benzoate chemical structure, C19H20BrN3O5, CAS 765934-63-2
Methyl 4-(4-acetylpiperazin-1-yl)-3-[(5-bromofuran-2-carbonyl)amino]benzoate
CAS 765934-63-2C19H20BrN3O5
Methyl 3-(2-furylcarbonylamino)-4-(4-methylpiperazinyl)benzoate chemical structure, C18H21N3O4, CAS 876889-27-9
Methyl 3-(2-furylcarbonylamino)-4-(4-methylpiperazinyl)benzoate
CAS 876889-27-9C18H21N3O4
N-[2-(4-Acetylpiperazin-1-yl)phenyl]-5-bromofuran-2-carboxamide chemical structure, C17H18BrN3O3, CAS 895338-40-6
N-[2-(4-Acetylpiperazin-1-yl)phenyl]-5-bromofuran-2-carboxamide
CAS 895338-40-6C17H18BrN3O3
5-Bromo-N-[3-chloro-2-(4-isobutyryl-1-piperazinyl)phenyl]-2-furamide chemical structure, C19H21BrClN3O3, CAS 920427-01-6
5-Bromo-N-[3-chloro-2-(4-isobutyryl-1-piperazinyl)phenyl]-2-furamide
CAS 920427-01-6C19H21BrClN3O3
N-[3-Chloro-2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-5-nitrofuran-2-carboxamide chemical structure, C19H21ClN4O5, CAS 921136-25-6
N-[3-Chloro-2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-5-nitrofuran-2-carboxamide
CAS 921136-25-6C19H21ClN4O5
N-[2-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]furan-2-carboxamide chemical structure, C17H18ClN3O3, CAS 925095-91-6
N-[2-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]furan-2-carboxamide
CAS 925095-91-6C17H18ClN3O3
N-[2-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]-5-bromofuran-2-carboxamide chemical structure, C17H17BrClN3O3, CAS 925042-01-9
N-[2-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]-5-bromofuran-2-carboxamide
CAS 925042-01-9C17H17BrClN3O3
N-[5-Chloro-2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide chemical structure, C19H22ClN3O3, CAS 895344-83-9
N-[5-Chloro-2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide
CAS 895344-83-9C19H22ClN3O3
N-[2-(4-Butanoylpiperazin-1-yl)-5-chlorophenyl]furan-2-carboxamide chemical structure, C19H22ClN3O3, CAS 899129-62-5
N-[2-(4-Butanoylpiperazin-1-yl)-5-chlorophenyl]furan-2-carboxamide
CAS 899129-62-5C19H22ClN3O3
N-[2-(4-Propionyl-1-piperazinyl)phenyl]-2-furamide chemical structure, C18H21N3O3, CAS 900764-98-9
N-[2-(4-Propionyl-1-piperazinyl)phenyl]-2-furamide
CAS 900764-98-9C18H21N3O3