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Murcko scaffold

Ring system with 3 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
10
With full pages
7
Scaffold SMILES

O=C(Nc1ccccc1N1CCOCC1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1N1CCOCC1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-[2-(4-Morpholinyl)-5-(trifluoromethyl)phenyl]-2-thiophenecarboxamide chemical structure, C16H15F3N2O2S, CAS 402481-36-1
N-[2-(4-Morpholinyl)-5-(trifluoromethyl)phenyl]-2-thiophenecarboxamide
CAS 402481-36-1C16H15F3N2O2S
N-(2-Morpholin-4-ylphenyl)-5-nitrothiophene-2-carboxamide chemical structure, C15H15N3O4S, CAS 745069-00-5
N-(2-Morpholin-4-ylphenyl)-5-nitrothiophene-2-carboxamide
CAS 745069-00-5C15H15N3O4S
5-Ethyl-4-methyl-N-(2-morpholin-4-ylphenyl)thiophene-2-carboxamide chemical structure, C18H22N2O2S, CAS 796109-99-4
5-Ethyl-4-methyl-N-(2-morpholin-4-ylphenyl)thiophene-2-carboxamide
CAS 796109-99-4C18H22N2O2S
N-(5-Chloro-2-morpholin-4-ylphenyl)thiophene-2-carboxamide chemical structure, C15H15ClN2O2S, CAS 879753-15-8
N-(5-Chloro-2-morpholin-4-ylphenyl)thiophene-2-carboxamide
CAS 879753-15-8C15H15ClN2O2S
N-[5-(Diethylsulfamoyl)-2-morpholin-4-ylphenyl]-3-methylthiophene-2-carboxamide chemical structure, C20H27N3O4S2, CAS 380568-81-0
N-[5-(Diethylsulfamoyl)-2-morpholin-4-ylphenyl]-3-methylthiophene-2-carboxamide
CAS 380568-81-0C20H27N3O4S2
5-Methyl-N-(2-morpholinophenyl)thiophene-2-carboxamide chemical structure, C16H18N2O2S, CAS 854135-42-5
5-Methyl-N-(2-morpholinophenyl)thiophene-2-carboxamide
CAS 854135-42-5C16H18N2O2S
Methyl 4-(4-morpholinyl)-3-[(2-thienylcarbonyl)amino]benzoate chemical structure, C17H18N2O4S, CAS 895074-60-9
Methyl 4-(4-morpholinyl)-3-[(2-thienylcarbonyl)amino]benzoate
CAS 895074-60-9C17H18N2O4S
N-(5-Methoxy-2-morpholin-4-ylphenyl)thiophene-2-carboxamide chemical structure, C16H18N2O3S, CAS 897548-33-3
N-(5-Methoxy-2-morpholin-4-ylphenyl)thiophene-2-carboxamide
CAS 897548-33-3C16H18N2O3S
4-Ethyl-5-methyl-N-[2-(morpholin-4-yl)phenyl]thiophene-2-carboxamide chemical structure, C18H22N2O2S, CAS 878950-87-9
4-Ethyl-5-methyl-N-[2-(morpholin-4-yl)phenyl]thiophene-2-carboxamide
CAS 878950-87-9C18H22N2O2S
N-(4-Chloro-2-morpholin-4-ylphenyl)thiophene-2-carboxamide chemical structure, C15H15ClN2O2S, CAS 881595-97-7
N-(4-Chloro-2-morpholin-4-ylphenyl)thiophene-2-carboxamide
CAS 881595-97-7C15H15ClN2O2S