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Murcko scaffold

Spiro[fluorene-9,4'-imidazolidine]-2',5'-dione scaffold

26 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
26
With full pages
5
Scaffold SMILES

O=C1NC(=O)C2(N1)c1ccccc1-c1ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Spiro[fluorene-9,4'-imidazolidine]-2',5'-dione page
Murcko scaffold O=C1NC(=O)C2(N1)c1ccccc1-c1ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

Imirestat chemical structure, C15H8F2N2O2, CAS 89391-50-4
Imirestat
CAS 89391-50-4C15H8F2N2O2
Alconil chemical structure, C15H9FN2O2, CAS 97677-19-5
Alconil
CAS 97677-19-5C15H9FN2O2
AL 3152 chemical structure, C16H10F2N2O3, CAS 126048-33-7
AL 3152
CAS 126048-33-7C16H10F2N2O3
AL 4114 chemical structure, C17H12F2N2O4, CAS 139911-05-0
AL 4114
CAS 139911-05-0C17H12F2N2O4
(4'R)-2,7-Difluoro-4-methoxyspiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione chemical structure, C16H10F2N2O3, CAS 145632-23-1
(4'R)-2,7-Difluoro-4-methoxyspiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione
CAS 145632-23-1C16H10F2N2O3
Spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H10N2O2, CAS 6278-92-8
Spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 6278-92-8C15H10N2O2
1',3'-Dichlorospiro[fluorene-9,5'-imidazolidine]-2',4'-dione chemical structure, C15H8Cl2N2O2, CAS 14910-26-0
1',3'-Dichlorospiro[fluorene-9,5'-imidazolidine]-2',4'-dione
CAS 14910-26-0C15H8Cl2N2O2
Spiro[9H-fluorene-9,4'-imidazolidine]-2',5'-dione, 2-bromo- chemical structure, C15H9BrN2O2, CAS 89391-42-4
Spiro[9H-fluorene-9,4'-imidazolidine]-2',5'-dione, 2-bromo-
CAS 89391-42-4C15H9BrN2O2
2,7-Dichlorospiro[fluorene-9,5'-imidazolidine]-2',4'-dione chemical structure, C15H8Cl2N2O2, CAS 14683-86-4
2,7-Dichlorospiro[fluorene-9,5'-imidazolidine]-2',4'-dione
CAS 14683-86-4C15H8Cl2N2O2
Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione, 2,7-diamino- chemical structure, C15H12N4O2, CAS 17917-57-6
Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione, 2,7-diamino-
CAS 17917-57-6C15H12N4O2
2,7-Dinitro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H8N4O6, CAS 17833-19-1
2,7-Dinitro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 17833-19-1C15H8N4O6
Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione, 2,7-difluoro-4-methoxy-, (S)- chemical structure, C16H10F2N2O3, CAS 145555-03-9
Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione, 2,7-difluoro-4-methoxy-, (S)-
CAS 145555-03-9C16H10F2N2O3
2-(Methylsulfanyl)-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C16H12N2O2S, CAS 97677-25-3
2-(Methylsulfanyl)-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 97677-25-3C16H12N2O2S
2-(Methanesulfonyl)-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C16H12N2O4S, CAS 89391-55-9
2-(Methanesulfonyl)-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-55-9C16H12N2O4S
3-Fluoro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H9FN2O2, CAS 89391-57-1
3-Fluoro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-57-1C15H9FN2O2
4-Fluoro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H9FN2O2, CAS 89391-58-2
4-Fluoro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-58-2C15H9FN2O2
2-Nitro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H9N3O4, CAS 89391-41-3
2-Nitro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-41-3C15H9N3O4
2,7-Dibromo-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H8Br2N2O2, CAS 89391-43-5
2,7-Dibromo-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-43-5C15H8Br2N2O2
4-Amino-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H11N3O2, CAS 89391-44-6
4-Amino-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-44-6C15H11N3O2
2-Amino-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H11N3O2, CAS 89391-45-7
2-Amino-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-45-7C15H11N3O2
2-Iodo-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H9IN2O2, CAS 89391-46-8
2-Iodo-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-46-8C15H9IN2O2
1-Methyl-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C16H12N2O2, CAS 89391-47-9
1-Methyl-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-47-9C16H12N2O2
3-Chloro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H9ClN2O2, CAS 89391-52-6
3-Chloro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-52-6C15H9ClN2O2
1-Fluoro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione chemical structure, C15H9FN2O2, CAS 89391-56-0
1-Fluoro-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
CAS 89391-56-0C15H9FN2O2