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Murcko scaffold

Ring system with 3 rings and 17 atoms

56 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
56
With full pages
3
Scaffold SMILES

c1ccc(Oc2ccc3ccncc3c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2ccc3ccncc3c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 56 of 56 chemicals

Roxadustat-d5 chemical structure, C19H16N2O5, CAS 2043026-13-5
Roxadustat-d5
CAS 2043026-13-5C19H16N2O5
Ethyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate chemical structure, C18H14ClNO4, CAS 2244489-55-0
Ethyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
CAS 2244489-55-0C18H14ClNO4
Ethyl 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetate chemical structure, C21H20N2O5, CAS 2370958-34-0
Ethyl 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetate
CAS 2370958-34-0C21H20N2O5
2-[[1-[(Dimethylamino)methyl]-4-hydroxy-7-phenoxyisoquinoline-3-carbonyl]amino]acetic acid chemical structure, C21H21N3O5, CAS 2599284-47-4
2-[[1-[(Dimethylamino)methyl]-4-hydroxy-7-phenoxyisoquinoline-3-carbonyl]amino]acetic acid
CAS 2599284-47-4C21H21N3O5
Methyl 2-[(4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]acetate chemical structure, C19H16N2O5, CAS 2599284-48-5
Methyl 2-[(4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]acetate
CAS 2599284-48-5C19H16N2O5
[3-[(2-Methoxy-2-oxoethyl)carbamoyl]-1-methyl-7-phenoxyisoquinolin-4-yl] 2,2-dimethylpropanoate chemical structure, C25H26N2O6, CAS 2731734-05-5
[3-[(2-Methoxy-2-oxoethyl)carbamoyl]-1-methyl-7-phenoxyisoquinolin-4-yl] 2,2-dimethylpropanoate
CAS 2731734-05-5C25H26N2O6
Methyl (7-(4-chlorophenoxy)-4-hydroxy-1-methylisoquinoline-3-carbonyl)glycinate chemical structure, C20H17ClN2O5, CAS 2699139-12-1
Methyl (7-(4-chlorophenoxy)-4-hydroxy-1-methylisoquinoline-3-carbonyl)glycinate
CAS 2699139-12-1C20H17ClN2O5
Deuterated roxadustat chemical structure, C19H16N2O5, CAS 3085640-01-0
Deuterated roxadustat
CAS 3085640-01-0C19H16N2O5