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Murcko scaffold

Ring system with 3 rings and 17 atoms

56 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
56
With full pages
3
Scaffold SMILES

c1ccc(Oc2ccc3ccncc3c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2ccc3ccncc3c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 56 chemicals

4-(Isoquinolin-7-yloxy)benzaldehyde chemical structure, C16H11NO2, CAS 57422-10-3
4-(Isoquinolin-7-yloxy)benzaldehyde
CAS 57422-10-3C16H11NO2
6-Methoxy-7-(4-methylphenoxy)isoquinoline chemical structure, C17H15NO2, CAS 57422-03-4
6-Methoxy-7-(4-methylphenoxy)isoquinoline
CAS 57422-03-4C17H15NO2
2-(7-(4-Chlorophenoxy)-4-hydroxy-1-methylisoquinoline-3-carboxamido)acetic acid chemical structure, C19H15ClN2O5, CAS 808119-86-0
2-(7-(4-Chlorophenoxy)-4-hydroxy-1-methylisoquinoline-3-carboxamido)acetic acid
CAS 808119-86-0C19H15ClN2O5
FG 4592 chemical structure, C19H16N2O5, CAS 808118-40-3
FG 4592
CAS 808118-40-3C19H16N2O5
Glycine, N-[[4-hydroxy-7-(4-methoxyphenoxy)-3-isoquinolinyl]carbonyl]- chemical structure, C19H16N2O6, CAS 808118-62-9
Glycine, N-[[4-hydroxy-7-(4-methoxyphenoxy)-3-isoquinolinyl]carbonyl]-
CAS 808118-62-9C19H16N2O6
Glycine, N-[(1-chloro-4-hydroxy-7-phenoxy-3-isoquinolinyl)carbonyl]- chemical structure, C18H13ClN2O5, CAS 808116-60-1
Glycine, N-[(1-chloro-4-hydroxy-7-phenoxy-3-isoquinolinyl)carbonyl]-
CAS 808116-60-1C18H13ClN2O5
Glycine, N-[(1-bromo-4-hydroxy-7-phenoxy-3-isoquinolinyl)carbonyl]- chemical structure, C18H13BrN2O5, CAS 808116-62-3
Glycine, N-[(1-bromo-4-hydroxy-7-phenoxy-3-isoquinolinyl)carbonyl]-
CAS 808116-62-3C18H13BrN2O5
2-[4-Hydroxy-1-methyl-7-(4-methoxy-phenoxy)-isoquinoline-3-carboxamido]acetic acid chemical structure, C20H18N2O6, CAS 808119-93-9
2-[4-Hydroxy-1-methyl-7-(4-methoxy-phenoxy)-isoquinoline-3-carboxamido]acetic acid
CAS 808119-93-9C20H18N2O6
Glycine, N-[(4-hydroxy-7-phenoxy-3-isoquinolinyl)carbonyl]- chemical structure, C18H14N2O5, CAS 708263-68-7
Glycine, N-[(4-hydroxy-7-phenoxy-3-isoquinolinyl)carbonyl]-
CAS 708263-68-7C18H14N2O5
Agn-PC-0NI9HW chemical structure, C17H16INO, CAS 57421-98-4
Agn-PC-0NI9HW
CAS 57421-98-4C17H16INO
Agn-PC-0NI9I1 chemical structure, C18H18INO3, CAS 57422-05-6
Agn-PC-0NI9I1
CAS 57422-05-6C18H18INO3
2-Isoquinolin-7-yloxy-5-methylsulfonylaniline chemical structure, C16H14N2O3S, CAS 330943-17-4
2-Isoquinolin-7-yloxy-5-methylsulfonylaniline
CAS 330943-17-4C16H14N2O3S
2-Isoquinolin-7-yloxyaniline chemical structure, C15H12N2O, CAS 330943-14-1
2-Isoquinolin-7-yloxyaniline
CAS 330943-14-1C15H12N2O
2-[[1-Cyano-7-(2,6-dimethylphenoxy)-4-hydroxyisoquinoline-3-carbonyl]amino]acetic acid chemical structure, C21H17N3O5, CAS 945739-86-6
2-[[1-Cyano-7-(2,6-dimethylphenoxy)-4-hydroxyisoquinoline-3-carbonyl]amino]acetic acid
CAS 945739-86-6C21H17N3O5
{[1-Cyano-4-hydroxy-7-(4-methoxy-phenoxy)-isoquinoline-3-carbonyl]-amino}-acetic acid chemical structure, C20H15N3O6, CAS 945739-90-2
{[1-Cyano-4-hydroxy-7-(4-methoxy-phenoxy)-isoquinoline-3-carbonyl]-amino}-acetic acid
CAS 945739-90-2C20H15N3O6
Roxadustat impurity N14 chemical structure, C17H14N2O3, CAS 2243809-28-9
Roxadustat impurity N14
CAS 2243809-28-9C17H14N2O3
7-(4-Methoxy-phenoxy)-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester chemical structure, C21H21NO5, CAS 808115-59-5
7-(4-Methoxy-phenoxy)-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester
CAS 808115-59-5C21H21NO5
Ethyl 4-ethoxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate chemical structure, C21H21NO4, CAS 808118-46-9
Ethyl 4-ethoxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate
CAS 808118-46-9C21H21NO4
4-Hydroxy-7-phenoxy-isoquinoline-3-carboxylic acid butyl ester chemical structure, C20H19NO4, CAS 808115-54-0
4-Hydroxy-7-phenoxy-isoquinoline-3-carboxylic acid butyl ester
CAS 808115-54-0C20H19NO4
4-Hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carboxylic acid butyl ester chemical structure, C21H21NO4, CAS 808116-09-8
4-Hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carboxylic acid butyl ester
CAS 808116-09-8C21H21NO4
Ethyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate chemical structure, C18H15NO4, CAS 808116-52-1
Ethyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
CAS 808116-52-1C18H15NO4
2-[(1-Ethyl-4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid chemical structure, C20H18N2O5, CAS 808120-20-9
2-[(1-Ethyl-4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
CAS 808120-20-9C20H18N2O5
4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid chemical structure, C17H13NO4, CAS 1421312-35-7
4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid
CAS 1421312-35-7C17H13NO4
3-Isoquinolinecarboxylic acid, 4-hydroxy-1-methyl-7-phenoxy-, methyl ester chemical structure, C18H15NO4, CAS 1421312-34-6
3-Isoquinolinecarboxylic acid, 4-hydroxy-1-methyl-7-phenoxy-, methyl ester
CAS 1421312-34-6C18H15NO4