Murcko scaffold
N-(1,3-Benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide scaffold
99 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 20
- Chemicals
- 99
- With full pages
- 14
Scaffold SMILES
O=C(CN1C(=O)CCC1=O)Nc1nc2ccccc2s1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 99 chemicals
![2-(2,5-Dioxopyrrolidin-1-yl)-N-(6-(methylsulfonyl)benzo[d]thiazol-2-yl)acetamide chemical structure, C14H13N3O5S2, CAS 361167-76-2](/s/VQBNKWFVNOHIDW-UHFFFAOYSA-N.svg)
2-(2,5-Dioxopyrrolidin-1-yl)-N-(6-(methylsulfonyl)benzo[d]thiazol-2-yl)acetamide
CAS 361167-76-2C14H13N3O5S2
![(E)-2-(2,5-Dioxopyrrolidin-1-yl)-N-(3-methyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)acetamide chemical structure, C14H12N4O5S, CAS 392324-88-8](/s/CLLOGDCUGGMNHB-UHFFFAOYSA-N.svg)
(E)-2-(2,5-Dioxopyrrolidin-1-yl)-N-(3-methyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)acetamide
CAS 392324-88-8C14H12N4O5S
2-(2,5-Dioxopyrrolidin-1-yl)-N-(6-methoxy-1,3-benzothiazol-2-yl)acetamide
CAS 360762-04-5C14H13N3O4S
2-(2,5-Dioxopyrrolidin-1-yl)-N-(6-fluoro-1,3-benzothiazol-2-yl)acetamide
CAS 476308-64-2C13H10FN3O3S
![(Z)-Methyl 3-allyl-2-((2-(2,5-dioxopyrrolidin-1-yl)acetyl)imino)-2,3-dihydrobenzo[d]thiazole-6-carboxylate chemical structure, C18H17N3O5S, CAS 865174-97-6](/s/IVHCFBJKAVGUCX-UHFFFAOYSA-N.svg)
(Z)-Methyl 3-allyl-2-((2-(2,5-dioxopyrrolidin-1-yl)acetyl)imino)-2,3-dihydrobenzo[d]thiazole-6-carboxylate
CAS 865174-97-6C18H17N3O5S
![(E)-2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)acetamide chemical structure, C15H15N3O4S, CAS 477294-97-6](/s/FEDSVOHKSSKZMI-UHFFFAOYSA-N.svg)
(E)-2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)acetamide
CAS 477294-97-6C15H15N3O4S
![(Z)-Methyl 2-(6-chloro-2-((2-(2,5-dioxopyrrolidin-1-yl)acetyl)imino)benzo[d]thiazol-3(2H)-yl)acetate chemical structure, C16H14ClN3O5S, CAS 941917-29-9](/s/UNJBFUXXNWZHJG-UHFFFAOYSA-N.svg)
(Z)-Methyl 2-(6-chloro-2-((2-(2,5-dioxopyrrolidin-1-yl)acetyl)imino)benzo[d]thiazol-3(2H)-yl)acetate
CAS 941917-29-9C16H14ClN3O5S
![(Z)-Methyl 2-(2-((2-(2,5-dioxopyrrolidin-1-yl)acetyl)imino)benzo[d]thiazol-3(2H)-yl)acetate chemical structure, C16H15N3O5S, CAS 941977-14-6](/s/CUQJYKWIRBRHSX-UHFFFAOYSA-N.svg)
(Z)-Methyl 2-(2-((2-(2,5-dioxopyrrolidin-1-yl)acetyl)imino)benzo[d]thiazol-3(2H)-yl)acetate
CAS 941977-14-6C16H15N3O5S
N-(4,5-Dimethyl-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 888409-79-8C15H15N3O3S
![(Z)-Methyl 2-(2-((2-(2,5-dioxopyrrolidin-1-yl)acetyl)imino)-6-(methylsulfonyl)benzo[d]thiazol-3(2H)-yl)acetate chemical structure, C17H17N3O7S2, CAS 865198-51-2](/s/HUTBIZKFHOMHNO-UHFFFAOYSA-N.svg)
(Z)-Methyl 2-(2-((2-(2,5-dioxopyrrolidin-1-yl)acetyl)imino)-6-(methylsulfonyl)benzo[d]thiazol-3(2H)-yl)acetate
CAS 865198-51-2C17H17N3O7S2
N-(4,6-Dimethyl-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 476308-63-1C15H15N3O3S
N-(6-Chloro-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 392324-48-0C13H10ClN3O3S
![(Z)-Methyl 2-(2-((2-(2,5-dioxopyrrolidin-1-yl)acetyl)imino)-6-methylbenzo[d]thiazol-3(2H)-yl)acetate chemical structure, C17H17N3O5S, CAS 941917-23-3](/s/VGRCSCCYMHBFOL-UHFFFAOYSA-N.svg)
(Z)-Methyl 2-(2-((2-(2,5-dioxopyrrolidin-1-yl)acetyl)imino)-6-methylbenzo[d]thiazol-3(2H)-yl)acetate
CAS 941917-23-3C17H17N3O5S
![(Z)-N-(6-Bromo-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C16H16BrN3O4S, CAS 864976-23-8](/s/NEZFPJZOGXFWQU-UHFFFAOYSA-N.svg)
(Z)-N-(6-Bromo-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 864976-23-8C16H16BrN3O4S
![(Z)-N-(3-Allyl-6-(methylsulfonyl)benzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C17H17N3O5S2, CAS 865175-74-2](/s/DVICCPWPMLIXMA-UHFFFAOYSA-N.svg)
(Z)-N-(3-Allyl-6-(methylsulfonyl)benzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 865175-74-2C17H17N3O5S2
![(Z)-2-(2,5-Dioxopyrrolidin-1-yl)-N-(6-nitro-3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)acetamide chemical structure, C16H12N4O5S, CAS 865181-70-0](/s/HKZRRZIHAGTLSH-UHFFFAOYSA-N.svg)
(Z)-2-(2,5-Dioxopyrrolidin-1-yl)-N-(6-nitro-3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)acetamide
CAS 865181-70-0C16H12N4O5S
![(Z)-N-(3-Allyl-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C16H16N4O5S2, CAS 1164457-94-6](/s/BMTLTZBRLFXUJM-UHFFFAOYSA-N.svg)
(Z)-N-(3-Allyl-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 1164457-94-6C16H16N4O5S2
N-(1,3-Benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 476308-57-3C13H11N3O3S
![(Z)-N-(6-Chloro-3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C16H12ClN3O3S, CAS 865181-22-2](/s/AONXYKCHLCZQBB-UHFFFAOYSA-N.svg)
(Z)-N-(6-Chloro-3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 865181-22-2C16H12ClN3O3S
N-(4,6-Difluoro-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 897618-21-2C13H9F2N3O3S
2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methyl-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)acetamide
CAS 1164527-40-5C17H15N3O3S
![(Z)-N-(3-Allyl-4-methylbenzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C17H17N3O3S, CAS 1321875-01-7](/s/NDKMVHKBTRTWST-UHFFFAOYSA-N.svg)
(Z)-N-(3-Allyl-4-methylbenzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 1321875-01-7C17H17N3O3S
N-(5,7-Dimethyl-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 868674-72-0C18H17N3O3S
2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methoxy-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)acetamide
CAS 868674-73-1C17H15N3O4S
- 2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-ethoxy-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)acetamide868674-74-2C18H17N3O4S
- N-(4-Chloro-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide868674-76-4C16H12ClN3O3S
- Ethyl 2-[2-[2-(2,5-dioxopyrrolidin-1-yl)acetyl]imino-5,7-dimethyl-1,3-benzothiazol-3-yl]acetate1322256-78-9C19H21N3O5S
- N-(5-Chloro-4-methyl-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide897759-64-7C14H12ClN3O3S
- N-(6-Chloro-4-methyl-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide897618-12-1C14H12ClN3O3S
- N-(4,7-Dichloro-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide897759-66-9C13H9Cl2N3O3S
- N-(7-Chloro-4-methyl-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide897618-13-2C14H12ClN3O3S
- N-(4,7-Dimethyl-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide897759-68-1C15H15N3O3S
- N-(5,7-Dimethyl-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide897618-14-3C15H15N3O3S
- 2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-ethyl-1,3-benzothiazol-2-yl)acetamide892851-36-4C15H15N3O3S
- N-(4,7-Dimethoxy-1,3-benzothiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide906784-16-5C15H15N3O5S
- (Z)-2-(2,5-Dioxopyrrolidin-1-yl)-N-(6-fluoro-3-propylbenzo[d]thiazol-2(3H)-ylidene)acetamide897499-62-6C16H16FN3O3S
- (Z)-2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-fluoro-3-propylbenzo[d]thiazol-2(3H)-ylidene)acetamide898370-96-2C16H16FN3O3S
- 2-(2,5-Dioxopyrrolidin-1-yl)-N-(3-propyl-1,3-benzothiazol-2-ylidene)acetamide897492-06-7C16H17N3O3S
- (Z)-N-(4,7-Dimethoxy-3-propylbenzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide898375-95-6C18H21N3O5S
- N-(6-Chlorobenzo[d]thiazol-2-yl)-N-(2-(diethylamino)ethyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide hydrochloride1216418-40-4C19H24Cl2N4O3S
- N-(3-(Dimethylamino)propyl)-2-(2,5-dioxopyrrolidin-1-yl)-N-(6-fluorobenzo[d]thiazol-2-yl)acetamide hydrochloride1216857-82-7C18H22ClFN4O3S
- N-(6-Chlorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide hydrochloride1216542-77-6C18H22Cl2N4O3S
- N-[3-(Dimethylamino)propyl]-2-(2,5-dioxopyrrolidin-1-yl)-N-(4-ethoxy-1,3-benzothiazol-2-yl)acetamide hydrochloride1216913-59-5C20H27ClN4O4S
- N-(6-Bromobenzo[d]thiazol-2-yl)-N-(2-(diethylamino)ethyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide hydrochloride1215610-36-8C19H24BrClN4O3S
- N-(6-Bromobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide hydrochloride1217174-40-7C18H22BrClN4O3S
- N-(3-(Dimethylamino)propyl)-2-(2,5-dioxopyrrolidin-1-yl)-N-(4-methylbenzo[d]thiazol-2-yl)acetamide hydrochloride1215660-90-4C19H25ClN4O3S
- N-(3-(Dimethylamino)propyl)-2-(2,5-dioxopyrrolidin-1-yl)-N-(4-fluorobenzo[d]thiazol-2-yl)acetamide hydrochloride1216953-96-6C18H22ClFN4O3S
- N-(4-Chlorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide hydrochloride1217111-94-8C18H22Cl2N4O3S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(CN1C(=O)c2ccccc2C1=O)Nc1nncs17 chemicals
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