Murcko scaffold
Ring system with 4 rings and 25 atoms
22 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 22
- With full pages
- 12
Scaffold SMILES
O=S(=O)(Nc1ccc(-c2ccc3nncn3n2)cc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 22 of 22 chemicals
![3-Fluoro-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide chemical structure, C18H14FN5O2S, CAS 894983-86-9](/s/SBTSVRTWMOEWQP-UHFFFAOYSA-N.svg)
3-Fluoro-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide
CAS 894983-86-9C18H14FN5O2S
![4-Methoxy-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide chemical structure, C19H17N5O3S, CAS 894984-98-6](/s/CKVNLOQDGLOVCM-UHFFFAOYSA-N.svg)
4-Methoxy-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide
CAS 894984-98-6C19H17N5O3S
![2,5-Difluoro-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide chemical structure, C17H11F2N5O2S, CAS 894069-15-9](/s/ATQZNQJQIURDIJ-UHFFFAOYSA-N.svg)
2,5-Difluoro-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide
CAS 894069-15-9C17H11F2N5O2S
![3-Methyl-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide chemical structure, C18H15N5O2S, CAS 894069-31-9](/s/XHTFHKDZPJZONU-UHFFFAOYSA-N.svg)
3-Methyl-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide
CAS 894069-31-9C18H15N5O2S
![2,5-Dimethoxy-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide chemical structure, C19H17N5O4S, CAS 894069-36-4](/s/ZDXZEGOGNDVDSO-UHFFFAOYSA-N.svg)
2,5-Dimethoxy-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide
CAS 894069-36-4C19H17N5O4S
![2,4-Dimethoxy-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide chemical structure, C19H17N5O4S, CAS 894069-37-5](/s/WEYQQCOZRZWPJT-UHFFFAOYSA-N.svg)
2,4-Dimethoxy-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide
CAS 894069-37-5C19H17N5O4S
![3-Fluoro-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide chemical structure, C17H12FN5O2S, CAS 894069-39-7](/s/RBIBSJSXEFJACH-UHFFFAOYSA-N.svg)
3-Fluoro-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide
CAS 894069-39-7C17H12FN5O2S
![2-Fluoro-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide chemical structure, C17H12FN5O2S, CAS 894069-40-0](/s/DRJOTILBRDMNLY-UHFFFAOYSA-N.svg)
2-Fluoro-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide
CAS 894069-40-0C17H12FN5O2S
![4-Acetyl-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide chemical structure, C19H15N5O3S, CAS 894069-42-2](/s/PHWYEAUPUUIRPW-UHFFFAOYSA-N.svg)
4-Acetyl-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide
CAS 894069-42-2C19H15N5O3S
![2-Chloro-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide chemical structure, C17H12ClN5O2S, CAS 894069-46-6](/s/WFMFNWYONQGFHH-UHFFFAOYSA-N.svg)
2-Chloro-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide
CAS 894069-46-6C17H12ClN5O2S
![4-Methyl-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide chemical structure, C18H15N5O2S, CAS 894069-57-9](/s/DXFWJJMXWYQTIM-UHFFFAOYSA-N.svg)
4-Methyl-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]benzenesulfonamide
CAS 894069-57-9C18H15N5O2S
![2,5-Difluoro-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide chemical structure, C18H13F2N5O2S, CAS 894069-71-7](/s/OOWBPTZIWDMQJY-UHFFFAOYSA-N.svg)
2,5-Difluoro-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide
CAS 894069-71-7C18H13F2N5O2S
![2,4,5-Trimethyl-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide chemical structure, C21H21N5O2S, CAS 894069-73-9](/s/ZYICISZJTAFUMC-UHFFFAOYSA-N.svg)
2,4,5-Trimethyl-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide
CAS 894069-73-9C21H21N5O2S
![N-(4-{3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)benzenesulfonamide chemical structure, C18H15N5O2S, CAS 894984-26-0](/s/WLTIYWWLDKLWRY-UHFFFAOYSA-N.svg)
N-(4-{3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}phenyl)benzenesulfonamide
CAS 894984-26-0C18H15N5O2S
![2,4-Difluoro-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide chemical structure, C18H13F2N5O2S, CAS 894986-18-6](/s/PAKGZUJYALBTKC-UHFFFAOYSA-N.svg)
2,4-Difluoro-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide
CAS 894986-18-6C18H13F2N5O2S
![N-(4-(N-(4-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)sulfamoyl)phenyl)acetamide chemical structure, C20H18N6O3S, CAS 894984-18-0](/s/ZEVUAUISTRELNN-UHFFFAOYSA-N.svg)
N-(4-(N-(4-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)sulfamoyl)phenyl)acetamide
CAS 894984-18-0C20H18N6O3S
![N-(4-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)-3-(trifluoromethyl)benzenesulfonamide chemical structure, C19H14F3N5O2S, CAS 891124-78-0](/s/ASUVADZFUSDZGP-UHFFFAOYSA-N.svg)
N-(4-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)-3-(trifluoromethyl)benzenesulfonamide
CAS 891124-78-0C19H14F3N5O2S
![N-(4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-nitrobenzenesulfonamide chemical structure, C17H12N6O4S, CAS 894069-60-4](/s/MUDJYWIGJWGBAG-UHFFFAOYSA-N.svg)
N-(4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-nitrobenzenesulfonamide
CAS 894069-60-4C17H12N6O4S
![2,5-Dimethoxy-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide chemical structure, C20H19N5O4S, CAS 894069-88-6](/s/BAFFLKWJDMIPCO-UHFFFAOYSA-N.svg)
2,5-Dimethoxy-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide
CAS 894069-88-6C20H19N5O4S
![2,4-Dimethoxy-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide chemical structure, C20H19N5O4S, CAS 894983-70-1](/s/CZJKWGOJIXUNAI-UHFFFAOYSA-N.svg)
2,4-Dimethoxy-N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzenesulfonamide
CAS 894983-70-1C20H19N5O4S
![N-(4-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-nitrobenzenesulfonamide chemical structure, C18H14N6O4S, CAS 894985-54-7](/s/WNOPVQCMIYOSQN-UHFFFAOYSA-N.svg)
N-(4-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-nitrobenzenesulfonamide
CAS 894985-54-7C18H14N6O4S
![N-(4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-ethylbenzenesulfonamide chemical structure, C19H17N5O2S, CAS 1170829-06-7](/s/QQDOVMVEVYWPON-UHFFFAOYSA-N.svg)
N-(4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)phenyl)-2-ethylbenzenesulfonamide
CAS 1170829-06-7C19H17N5O2S
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(CSc2ccc(-c3ccc4c(c3)OCO4)nn2)cc15 chemicals
O=C(Nc1ccccc1)N1CCN(c2ccc3nncn3n2)CC12 chemicals![Scaffold O=S(=O)(Nc1ccc(-c2cnc3c[nH]nc3n2)cc1)c1ccccc1](/scaffold/ZQBCWAIBSFIUDU-UHFFFAOYSA-N/structure.svg)
O=S(=O)(Nc1ccc(-c2cnc3c[nH]nc3n2)cc1)c1ccccc12 chemicals
c1cncc(CSc2ccc(-c3ccc4c(c3)OCO4)nn2)c11 chemical
O=C(Nc1cnc(-c2ccc3c(c2)OCO3)cn1)c1ccccc11 chemical
O=C(Nc1ccc(-c2ccc3nncn3n2)cc1)c1cccnc11 chemical![Scaffold O=C(Nc1ccc(-c2ccc3cn[nH]c3c2)cc1)N1CCNCC1](/scaffold/VHRIBTZVBORUQN-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccc(-c2ccc3cn[nH]c3c2)cc1)N1CCNCC11 chemical