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Murcko scaffold

Ring system with 4 rings and 25 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
10
With full pages
2
Scaffold SMILES

O=S(=O)(Nc1ccc(-c2cnc3c[nH]nc3n2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccc(-c2cnc3c[nH]nc3n2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Sgk1-IN-1 chemical structure, C17H12ClFN6O2S, CAS 1279829-87-6
Sgk1-IN-1
CAS 1279829-87-6C17H12ClFN6O2S
SGK1 inhibitor chemical structure, C17H12Cl2N6O2S, CAS 1426214-51-8
SGK1 inhibitor
CAS 1426214-51-8C17H12Cl2N6O2S
Sgk1-IN-2 chemical structure, C17H12Cl2N6O2S, CAS 1426214-64-3
Sgk1-IN-2
CAS 1426214-64-3C17H12Cl2N6O2S
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-5-chloro-2-hydrazinylbenzenesulfonamide chemical structure, C17H15ClN8O2S, CAS 1426214-70-1
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-5-chloro-2-hydrazinylbenzenesulfonamide
CAS 1426214-70-1C17H15ClN8O2S
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)-2-fluorophenyl]-2,5-dichlorobenzenesulfonamide chemical structure, C17H11Cl2FN6O2S, CAS 1426214-68-7
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)-2-fluorophenyl]-2,5-dichlorobenzenesulfonamide
CAS 1426214-68-7C17H11Cl2FN6O2S
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)-2-fluorophenyl]-2,3-dichlorobenzenesulfonamide chemical structure, C17H11Cl2FN6O2S, CAS 1426214-71-2
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)-2-fluorophenyl]-2,3-dichlorobenzenesulfonamide
CAS 1426214-71-2C17H11Cl2FN6O2S
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2-chloro-5-methoxybenzenesulfonamide chemical structure, C18H15ClN6O3S, CAS 1426214-90-5
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2-chloro-5-methoxybenzenesulfonamide
CAS 1426214-90-5C18H15ClN6O3S
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,4,6-trichlorobenzenesulfonamide chemical structure, C17H11Cl3N6O2S, CAS 1279839-27-8
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,4,6-trichlorobenzenesulfonamide
CAS 1279839-27-8C17H11Cl3N6O2S
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3,4-trichlorobenzenesulfonamide chemical structure, C17H11Cl3N6O2S, CAS 1279877-61-0
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3,4-trichlorobenzenesulfonamide
CAS 1279877-61-0C17H11Cl3N6O2S
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2-chlorobenzenesulfonamide chemical structure, C17H13ClN6O2S, CAS 1428182-96-0
N-[4-(3-Amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2-chlorobenzenesulfonamide
CAS 1428182-96-0C17H13ClN6O2S