Murcko scaffold
N-Phenyl-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide scaffold
43 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 24
- Chemicals
- 43
- With full pages
- 2
Scaffold SMILES
O=C(Nc1ccccc1)N1CCN(c2ccc3nncn3n2)CC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 43 of 43 chemicals
![4-{[1,2,4]Triazolo[4,3-b]pyridazin-6-yl}-N-[2-(trifluoromethyl)phenyl]piperazine-1-carboxamide chemical structure, C17H16F3N7O, CAS 904576-68-7](/s/BVAZWOSZHZBHJC-UHFFFAOYSA-N.svg)
4-{[1,2,4]Triazolo[4,3-b]pyridazin-6-yl}-N-[2-(trifluoromethyl)phenyl]piperazine-1-carboxamide
CAS 904576-68-7C17H16F3N7O
![4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(4-fluorophenyl)piperazine-1-carboxamide chemical structure, C16H16FN7O, CAS 904576-72-3](/s/WCEXMWONAJYERU-UHFFFAOYSA-N.svg)
4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(4-fluorophenyl)piperazine-1-carboxamide
CAS 904576-72-3C16H16FN7O
![N-Phenyl-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C16H17N7O, CAS 1040639-55-1](/s/KEJLOABRNXXDFA-UHFFFAOYSA-N.svg)
N-Phenyl-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1040639-55-1C16H17N7O
![4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(2,4-difluorophenyl)piperazine-1-carboxamide chemical structure, C16H15F2N7O, CAS 1040639-62-0](/s/SZBRPFIIZMKENA-UHFFFAOYSA-N.svg)
4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(2,4-difluorophenyl)piperazine-1-carboxamide
CAS 1040639-62-0C16H15F2N7O
![N-(3,4-Difluorophenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C16H15F2N7O, CAS 1060205-12-0](/s/GRMNELVKCKLMMX-UHFFFAOYSA-N.svg)
N-(3,4-Difluorophenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1060205-12-0C16H15F2N7O
![N-(2-Ethylphenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C18H21N7O, CAS 1060205-35-7](/s/PDKFNCRYPIQCBS-UHFFFAOYSA-N.svg)
N-(2-Ethylphenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1060205-35-7C18H21N7O
![4-{[1,2,4]Triazolo[4,3-b]pyridazin-6-yl}-N-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide chemical structure, C17H16F3N7O, CAS 1058447-40-7](/s/ZOXHLJHELSFIFI-UHFFFAOYSA-N.svg)
4-{[1,2,4]Triazolo[4,3-b]pyridazin-6-yl}-N-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide
CAS 1058447-40-7C17H16F3N7O
![N-(2,3-Dimethylphenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C18H21N7O, CAS 1058204-59-3](/s/ZDYJCVCVMGCXBR-UHFFFAOYSA-N.svg)
N-(2,3-Dimethylphenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1058204-59-3C18H21N7O
![N-(4-Ethoxyphenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C18H21N7O2, CAS 1060205-43-7](/s/GTZCNLZMTGISTG-UHFFFAOYSA-N.svg)
N-(4-Ethoxyphenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1060205-43-7C18H21N7O2
![N-(3,5-Dimethylphenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C18H21N7O, CAS 1058237-08-3](/s/MQSKTDCMRNXARP-UHFFFAOYSA-N.svg)
N-(3,5-Dimethylphenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1058237-08-3C18H21N7O
![N-(3-Fluoro-4-methylphenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C17H18FN7O, CAS 1060205-51-7](/s/ZVNKEJHROPQUSH-UHFFFAOYSA-N.svg)
N-(3-Fluoro-4-methylphenyl)-4-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1060205-51-7C17H18FN7O
![4-{[1,2,4]Triazolo[4,3-b]pyridazin-6-yl}-N-[4-(trifluoromethoxy)phenyl]piperazine-1-carboxamide chemical structure, C17H16F3N7O2, CAS 1058237-10-7](/s/RVBOMZRDKPFNBY-UHFFFAOYSA-N.svg)
4-{[1,2,4]Triazolo[4,3-b]pyridazin-6-yl}-N-[4-(trifluoromethoxy)phenyl]piperazine-1-carboxamide
CAS 1058237-10-7C17H16F3N7O2
![4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(3,4-dichlorophenyl)piperazine-1-carboxamide chemical structure, C16H15Cl2N7O, CAS 1060206-31-6](/s/FZVGLCHOAKBVGW-UHFFFAOYSA-N.svg)
4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(3,4-dichlorophenyl)piperazine-1-carboxamide
CAS 1060206-31-6C16H15Cl2N7O
![4-{3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-N-phenylpiperazine-1-carboxamide chemical structure, C17H19N7O, CAS 1040639-85-7](/s/FGJGYLQWYGILMB-UHFFFAOYSA-N.svg)
4-{3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-N-phenylpiperazine-1-carboxamide
CAS 1040639-85-7C17H19N7O
![N-(2,4-Difluorophenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C17H17F2N7O, CAS 1040639-93-7](/s/YADGSDVEFANBJE-UHFFFAOYSA-N.svg)
N-(2,4-Difluorophenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1040639-93-7C17H17F2N7O
![N-(3-Fluorophenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C17H18FN7O, CAS 1058228-33-3](/s/JQTWSIBCXNRLDS-UHFFFAOYSA-N.svg)
N-(3-Fluorophenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1058228-33-3C17H18FN7O
![N-(2-Ethylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C19H23N7O, CAS 1058448-10-4](/s/IXVDHLGSGAVNBX-UHFFFAOYSA-N.svg)
N-(2-Ethylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1058448-10-4C19H23N7O
![N-(2,4-Dimethylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C19H23N7O, CAS 1058228-34-4](/s/ANYZYNGIGKAEBT-UHFFFAOYSA-N.svg)
N-(2,4-Dimethylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1058228-34-4C19H23N7O
![4-{3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-N-[2-(trifluoromethyl)phenyl]piperazine-1-carboxamide chemical structure, C18H18F3N7O, CAS 1060208-13-0](/s/OPJHLHCDJVYTTI-UHFFFAOYSA-N.svg)
4-{3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-N-[2-(trifluoromethyl)phenyl]piperazine-1-carboxamide
CAS 1060208-13-0C18H18F3N7O
![N-(2,3-Dimethylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C19H23N7O, CAS 1058448-12-6](/s/OJOPBQNQZZTYOK-UHFFFAOYSA-N.svg)
N-(2,3-Dimethylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1058448-12-6C19H23N7O
![N-(4-Ethoxyphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C19H23N7O2, CAS 1058237-42-5](/s/KBQMBFCKAHAQTN-UHFFFAOYSA-N.svg)
N-(4-Ethoxyphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1058237-42-5C19H23N7O2
![N-(3,5-Dimethylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C19H23N7O, CAS 1060208-21-0](/s/KFIDDUBKOHCGPU-UHFFFAOYSA-N.svg)
N-(3,5-Dimethylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1060208-21-0C19H23N7O
![N-(3-Fluoro-4-methylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C18H20FN7O, CAS 1058237-43-6](/s/QZURVCGQLGEHIP-UHFFFAOYSA-N.svg)
N-(3-Fluoro-4-methylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1058237-43-6C18H20FN7O
![N-(3,4-Difluorophenyl)-4-{3-ethyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide chemical structure, C18H19F2N7O, CAS 1060175-18-9](/s/RWYDJGSRLTXURS-UHFFFAOYSA-N.svg)
N-(3,4-Difluorophenyl)-4-{3-ethyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide
CAS 1060175-18-9C18H19F2N7O
- N-(3,4-Dimethylphenyl)-4-{3-ethyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine-1-carboxamide1058255-77-8C20H25N7O
- 4-{3-Ethyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-N-[4-(trifluoromethyl)phenyl]piperazine-1-carboxamide1058228-75-3C19H20F3N7O
- N-(2,5-Difluorophenyl)-4-(3-ethyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperazine-1-carboxamide1058255-83-6C18H19F2N7O
- N-(3,4-Dichlorophenyl)-4-(3-ethyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperazine-1-carboxamide1058255-91-6C18H19Cl2N7O
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(4-chlorophenyl)piperazine-1-carboxamide904576-65-4C16H16ClN7O
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(2,4-dimethylphenyl)piperazine-1-carboxamide1058237-07-2C18H21N7O
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(2-ethoxyphenyl)piperazine-1-carboxamide1058204-60-6C18H21N7O2
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(2-methoxy-5-methylphenyl)piperazine-1-carboxamide1058237-09-4C18H21N7O2
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(3,5-dimethoxyphenyl)piperazine-1-carboxamide1058237-11-8C18H21N7O3
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(5-chloro-2-methoxyphenyl)piperazine-1-carboxamide1060206-23-6C17H18ClN7O2
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(2,5-dichlorophenyl)piperazine-1-carboxamide1058204-71-9C16H15Cl2N7O
- N-(2,5-Dichlorophenyl)-4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperazine-1-carboxamide1058486-67-1C17H17Cl2N7O
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(2,5-dimethoxyphenyl)piperazine-1-carboxamide1060205-20-0C18H21N7O3
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(4-isopropylphenyl)piperazine-1-carboxamide1058447-46-3C19H23N7O
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(2,5-difluorophenyl)piperazine-1-carboxamide1058204-63-9C16H15F2N7O
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(3-chloro-4-fluorophenyl)piperazine-1-carboxamide1058204-70-8C16H15ClFN7O
- N-(3,4-Dimethoxyphenyl)-4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperazine-1-carboxamide1060207-89-7C19H23N7O3
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(4-(trifluoromethyl)phenyl)piperazine-1-carboxamide1060205-59-5C17H16F3N7O
- 4-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-(3-chlorophenyl)piperazine-1-carboxamide1058204-69-5C16H16ClN7O
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