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Murcko scaffold

2-Hydroxy benzimidazole scaffold

883 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
883
With full pages
159
Scaffold SMILES

O=c1[nH]c2ccccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Hydroxy benzimidazole page
Murcko scaffold O=c1[nH]c2ccccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 883 chemicals

4-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)-1,3-dihydro-2H-benzimidazol-2-one chemical structure, C14H21N3O3, CAS 81047-99-6
4-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)-1,3-dihydro-2H-benzimidazol-2-one
CAS 81047-99-6C14H21N3O3
2-Hydroxy benzimidazole chemical structure, C7H6N2O, CAS 615-16-7
2-Hydroxy benzimidazole
CAS 615-16-7C7H6N2O
5-Amino-2-hydroxybenzimidazole chemical structure, C7H7N3O, CAS 95-23-8
5-Amino-2-hydroxybenzimidazole
CAS 95-23-8C7H7N3O
5,6-Dimethyl-1H-benzo[d]imidazol-2(3H)-one chemical structure, C9H10N2O, CAS 2033-30-9
5,6-Dimethyl-1H-benzo[d]imidazol-2(3H)-one
CAS 2033-30-9C9H10N2O
1-Ebio chemical structure, C9H10N2O, CAS 10045-45-1
1-Ebio
CAS 10045-45-1C9H10N2O
4,5,6,7-Tetrabromo-1,3-dihydro-1,3-bis(2-hydroxyethyl)-2H-benzimidazol-2-one chemical structure, C11H10Br4N2O3, CAS 56315-67-4
4,5,6,7-Tetrabromo-1,3-dihydro-1,3-bis(2-hydroxyethyl)-2H-benzimidazol-2-one
CAS 56315-67-4C11H10Br4N2O3
1,3-Dihydro-1-(1-methylvinyl)-2H-benzimidazol-2-one chemical structure, C10H10N2O, CAS 52099-72-6
1,3-Dihydro-1-(1-methylvinyl)-2H-benzimidazol-2-one
CAS 52099-72-6C10H10N2O
5-(Acetoacetylamino)benzimidazolone chemical structure, C11H11N3O3, CAS 26576-46-5
5-(Acetoacetylamino)benzimidazolone
CAS 26576-46-5C11H11N3O3
1H-Benzimidazole-1-propanoic acid, 2,3-dihydro-2-oxo- chemical structure, C10H10N2O3, CAS 75655-44-6
1H-Benzimidazole-1-propanoic acid, 2,3-dihydro-2-oxo-
CAS 75655-44-6C10H10N2O3
5-Chloro-1,3-dihydro-2H-benzimidazol-2-one chemical structure, C7H5ClN2O, CAS 2034-23-3
5-Chloro-1,3-dihydro-2H-benzimidazol-2-one
CAS 2034-23-3C7H5ClN2O
5-Methylbenzimidazolone chemical structure, C8H8N2O, CAS 5400-75-9
5-Methylbenzimidazolone
CAS 5400-75-9C8H8N2O
(2-Oxo-1,3-dihydrobenzimidazol-5-yl)arsonous acid chemical structure, C7H7AsN2O3, CAS 5410-87-7
(2-Oxo-1,3-dihydrobenzimidazol-5-yl)arsonous acid
CAS 5410-87-7C7H7AsN2O3
2-(3-(Carboxymethyl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)acetic acid chemical structure, C11H10N2O5, CAS 1848-99-3
2-(3-(Carboxymethyl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)acetic acid
CAS 1848-99-3C11H10N2O5
1,3-Dimethyl-2,3-dihydro-1H-1,3-benzodiazol-2-one chemical structure, C9H10N2O, CAS 3097-21-0
1,3-Dimethyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
CAS 3097-21-0C9H10N2O
Diethyl 2,2'-(2-oxo-1H-benzimidazole-1,3(2H)-diyl)diacetate chemical structure, C15H18N2O5, CAS 83330-80-7
Diethyl 2,2'-(2-oxo-1H-benzimidazole-1,3(2H)-diyl)diacetate
CAS 83330-80-7C15H18N2O5
Ethyl 2-oxo-2,3-dihydro-1H-benzo[D]imidazole-1-carboxylate chemical structure, C10H10N2O3, CAS 41120-23-4
Ethyl 2-oxo-2,3-dihydro-1H-benzo[D]imidazole-1-carboxylate
CAS 41120-23-4C10H10N2O3
5-Amino-1,3-dihydro-6-methyl-2H-benzimidazol-2-one chemical structure, C8H9N3O, CAS 67014-36-2
5-Amino-1,3-dihydro-6-methyl-2H-benzimidazol-2-one
CAS 67014-36-2C8H9N3O
1,3-Diacetylbenzimidazol-2-one chemical structure, C11H10N2O3, CAS 2735-73-1
1,3-Diacetylbenzimidazol-2-one
CAS 2735-73-1C11H10N2O3
1-Methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one chemical structure, C8H8N2O, CAS 1849-01-0
1-Methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
CAS 1849-01-0C8H8N2O
2,2,2-Trifluoro-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)acetamide chemical structure, C9H6F3N3O2, CAS 355135-47-6
2,2,2-Trifluoro-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)acetamide
CAS 355135-47-6C9H6F3N3O2
1,3-Dihydro-5-methoxy-2H-benzimidazol-2-one chemical structure, C8H8N2O2, CAS 2080-75-3
1,3-Dihydro-5-methoxy-2H-benzimidazol-2-one
CAS 2080-75-3C8H8N2O2
RefChem:381787 chemical structure, C9H9N3O2, CAS 91085-68-6
RefChem:381787
CAS 91085-68-6C9H9N3O2
2,3-Dihydro-beta-methyl-2-oxo-1H-benzimidazole-5-propanoic acid chemical structure, C11H12N2O3, CAS 21190-17-0
2,3-Dihydro-beta-methyl-2-oxo-1H-benzimidazole-5-propanoic acid
CAS 21190-17-0C11H12N2O3
1,3,5-Trimethyl-1,3-dihydro-2H-benzimidazol-2-one chemical structure, C10H12N2O, CAS 55327-67-8
1,3,5-Trimethyl-1,3-dihydro-2H-benzimidazol-2-one
CAS 55327-67-8C10H12N2O