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Murcko scaffold

Ring system with 3 rings and 15 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
10
With full pages
2
Scaffold SMILES

O=C1CCCC(c2ncc[nH]2)N1C1CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC(c2ncc[nH]2)N1C1CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Rac-(2R,3R)-1-cyclopropyl-2-(1-methyl-1H-imidazol-2-yl)-6-oxopiperidine-3-carboxylic acid chemical structure, C13H17N3O3, CAS 2307754-11-4
Rac-(2R,3R)-1-cyclopropyl-2-(1-methyl-1H-imidazol-2-yl)-6-oxopiperidine-3-carboxylic acid
CAS 2307754-11-4C13H17N3O3
rac-(5R,6R)-5-Amino-1-cyclopropyl-6-(1-methyl-1H-imidazol-2-yl)piperidin-2-one, trans chemical structure, C12H18N4O, CAS 2044705-59-9
rac-(5R,6R)-5-Amino-1-cyclopropyl-6-(1-methyl-1H-imidazol-2-yl)piperidin-2-one, trans
CAS 2044705-59-9C12H18N4O
rac-(5R,6S)-5-(Aminomethyl)-1-cyclopropyl-6-(1-methyl-1H-imidazol-2-yl)piperidin-2-one chemical structure, C13H20N4O, CAS 2307782-60-9
rac-(5R,6S)-5-(Aminomethyl)-1-cyclopropyl-6-(1-methyl-1H-imidazol-2-yl)piperidin-2-one
CAS 2307782-60-9C13H20N4O
Rel-(2S,3S)-1-cyclopropyl-2-(1-methyl-1H-imidazol-2-yl)-6-oxopiperidine-3-carboxamide chemical structure, C13H18N4O2, CAS 2044706-27-4
Rel-(2S,3S)-1-cyclopropyl-2-(1-methyl-1H-imidazol-2-yl)-6-oxopiperidine-3-carboxamide
CAS 2044706-27-4C13H18N4O2
Methyl (E)-4-[[(2R,3S)-1-cyclopropyl-2-(1-methylimidazol-2-yl)-6-oxopiperidin-3-yl]methylamino]-4-oxobut-2-enoate chemical structure, C18H24N4O4, CAS 2411181-11-6
Methyl (E)-4-[[(2R,3S)-1-cyclopropyl-2-(1-methylimidazol-2-yl)-6-oxopiperidin-3-yl]methylamino]-4-oxobut-2-enoate
CAS 2411181-11-6C18H24N4O4
1-Cyclopropyl-2-(1-methyl-1H-imidazol-2-yl)-6-oxopiperidine-3-carboxamide chemical structure, C13H18N4O2, CAS 2138216-54-1
1-Cyclopropyl-2-(1-methyl-1H-imidazol-2-yl)-6-oxopiperidine-3-carboxamide
CAS 2138216-54-1C13H18N4O2
5-Amino-1-cyclopropyl-6-(1-methyl-1H-imidazol-2-yl)piperidin-2-one chemical structure, C12H18N4O, CAS 2137457-43-1
5-Amino-1-cyclopropyl-6-(1-methyl-1H-imidazol-2-yl)piperidin-2-one
CAS 2137457-43-1C12H18N4O
5-(Aminomethyl)-1-cyclopropyl-6-(1-methyl-1H-imidazol-2-yl)piperidin-2-one chemical structure, C13H20N4O, CAS 2137731-12-3
5-(Aminomethyl)-1-cyclopropyl-6-(1-methyl-1H-imidazol-2-yl)piperidin-2-one
CAS 2137731-12-3C13H20N4O
1-Cyclopropyl-2-(1-methyl-1H-imidazol-2-yl)-6-oxopiperidine-3-carboxylic acid chemical structure, C13H17N3O3, CAS 2137517-80-5
1-Cyclopropyl-2-(1-methyl-1H-imidazol-2-yl)-6-oxopiperidine-3-carboxylic acid
CAS 2137517-80-5C13H17N3O3
rac-(5R,6R)-5-Amino-1-cyclopropyl-6-(1-methyl-1H-imidazol-2-yl)piperidin-2-one chemical structure, C12H18N4O, CAS 2307756-58-5
rac-(5R,6R)-5-Amino-1-cyclopropyl-6-(1-methyl-1H-imidazol-2-yl)piperidin-2-one
CAS 2307756-58-5C12H18N4O