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Murcko scaffold

Ring system with 4 rings and 33 atoms

27 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
33
Chemicals
27
With full pages
22
Scaffold SMILES

O=C(NN=Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)Nc1cccc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)Nc1cccc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

4-((E)-{2-[2-(1-Naphthylamino)-2-oxoacetyl]hydrazono}methyl)phenyl 4-propoxybenzoate chemical structure, C29H25N3O5, CAS 765273-84-5
4-((E)-{2-[2-(1-Naphthylamino)-2-oxoacetyl]hydrazono}methyl)phenyl 4-propoxybenzoate
CAS 765273-84-5C29H25N3O5
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-bromobenzoate chemical structure, C26H18BrN3O4, CAS 764652-95-1
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-bromobenzoate
CAS 764652-95-1C26H18BrN3O4
2-Methoxy-4-((E)-{[(1-naphthylamino)(oxo)acetyl]hydrazono}methyl)phenyl 4-ethoxybenzoate chemical structure, C29H25N3O6, CAS 767288-41-5
2-Methoxy-4-((E)-{[(1-naphthylamino)(oxo)acetyl]hydrazono}methyl)phenyl 4-ethoxybenzoate
CAS 767288-41-5C29H25N3O6
2-Meo-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)phenyl 4-butoxybenzoate chemical structure, C31H29N3O6, CAS 767314-01-2
2-Meo-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)phenyl 4-butoxybenzoate
CAS 767314-01-2C31H29N3O6
2-Methoxy-4-((E)-{[(1-naphthylamino)(oxo)acetyl]hydrazono}methyl)phenyl 2-chlorobenzoate chemical structure, C27H20ClN3O5, CAS 769152-77-4
2-Methoxy-4-((E)-{[(1-naphthylamino)(oxo)acetyl]hydrazono}methyl)phenyl 2-chlorobenzoate
CAS 769152-77-4C27H20ClN3O5
2-Meo-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)phenyl 4-methylbenzoate chemical structure, C28H23N3O5, CAS 765281-31-0
2-Meo-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)phenyl 4-methylbenzoate
CAS 765281-31-0C28H23N3O5
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 2-methylbenzoate chemical structure, C27H21N3O4, CAS 764653-86-3
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 2-methylbenzoate
CAS 764653-86-3C27H21N3O4
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 3-methylbenzoate chemical structure, C27H21N3O4, CAS 769152-22-9
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 3-methylbenzoate
CAS 769152-22-9C27H21N3O4
2-Ethoxy-4-((E)-{[(1-naphthylamino)(oxo)acetyl]hydrazono}methyl)phenyl 4-ethoxybenzoate chemical structure, C30H27N3O6, CAS 769148-66-5
2-Ethoxy-4-((E)-{[(1-naphthylamino)(oxo)acetyl]hydrazono}methyl)phenyl 4-ethoxybenzoate
CAS 769148-66-5C30H27N3O6
2-Ethoxy-4-(2-((1-naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl benzoate chemical structure, C28H23N3O5, CAS 769153-13-1
2-Ethoxy-4-(2-((1-naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl benzoate
CAS 769153-13-1C28H23N3O5
2-Ethoxy-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)PH 4-methoxybenzoate chemical structure, C29H25N3O6, CAS 769152-20-7
2-Ethoxy-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)PH 4-methoxybenzoate
CAS 769152-20-7C29H25N3O6
2-Ethoxy-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)PH 2,4-dichlorobenzoate chemical structure, C28H21Cl2N3O5, CAS 764657-09-2
2-Ethoxy-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)PH 2,4-dichlorobenzoate
CAS 764657-09-2C28H21Cl2N3O5
2-Meo-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)PH 3,4-dichlorobenzoate chemical structure, C27H19Cl2N3O5, CAS 769152-48-9
2-Meo-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)PH 3,4-dichlorobenzoate
CAS 769152-48-9C27H19Cl2N3O5
2-Ethoxy-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C28H22ClN3O5, CAS 769152-45-6
2-Ethoxy-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 769152-45-6C28H22ClN3O5
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-butoxybenzoate chemical structure, C30H27N3O5, CAS 767314-10-3
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-butoxybenzoate
CAS 767314-10-3C30H27N3O5
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 3,4-dimethoxybenzoate chemical structure, C28H23N3O6, CAS 769157-25-7
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 3,4-dimethoxybenzoate
CAS 769157-25-7C28H23N3O6
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate chemical structure, C28H23N3O5, CAS 769148-24-5
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate
CAS 769148-24-5C28H23N3O5
2-Meo-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)phenyl 4-propoxybenzoate chemical structure, C30H27N3O6, CAS 769151-50-0
2-Meo-4-(2-((1-naphthylamino)(oxo)AC)carbohydrazonoyl)phenyl 4-propoxybenzoate
CAS 769151-50-0C30H27N3O6
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-methoxybenzoate chemical structure, C27H21N3O5, CAS 765281-85-4
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-methoxybenzoate
CAS 765281-85-4C27H21N3O5
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 2-fluorobenzoate chemical structure, C26H18FN3O4, CAS 765281-83-2
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 2-fluorobenzoate
CAS 765281-83-2C26H18FN3O4
2-Methoxy-4-((E)-{[(1-naphthylamino)(oxo)acetyl]hydrazono}methyl)phenyl 4-methoxybenzoate chemical structure, C28H23N3O6, CAS 767333-95-9
2-Methoxy-4-((E)-{[(1-naphthylamino)(oxo)acetyl]hydrazono}methyl)phenyl 4-methoxybenzoate
CAS 767333-95-9C28H23N3O6
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 2-chlorobenzoate chemical structure, C26H18ClN3O4, CAS 880054-71-7
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 2-chlorobenzoate
CAS 880054-71-7C26H18ClN3O4
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-methylbenzoate chemical structure, C27H21N3O4, CAS 881683-10-9
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-methylbenzoate
CAS 881683-10-9C27H21N3O4
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl benzoate chemical structure, C26H19N3O4, CAS 881469-69-8
4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenyl benzoate
CAS 881469-69-8C26H19N3O4