Murcko scaffold
Ring system with 4 rings and 28 atoms
18 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 28
- Chemicals
- 18
- With full pages
- 5
Scaffold SMILES
O=C(NCC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1)c1cccs1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 18 of 18 chemicals
Rivaroxaban, Xarelto, BAY 59-7939
CAS 482306-32-1C19H18ClN3O5S
Rivaroxaban
CAS 366789-02-8C19H18ClN3O5S
![5-Chloro-N-methyl-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide chemical structure, C20H20ClN3O5S, CAS 865479-76-1](/s/FAQYFCCIHWKTEZ-HNNXBMFYSA-N.svg)
5-Chloro-N-methyl-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide
CAS 865479-76-1C20H20ClN3O5S
Rivaroxaban, (R)-
CAS 865479-71-6C19H18ClN3O5S
5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)(~2~H_4_)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide
CAS 1132681-38-9C19H18ClN3O5S
![5-Chloro-N-[[3-[4-(3-hydroxy-5-oxomorpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide chemical structure, C19H18ClN3O6S, CAS 1159977-46-4](/s/DZZZOMQJUMULNY-UHFFFAOYSA-N.svg)
5-Chloro-N-[[3-[4-(3-hydroxy-5-oxomorpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
CAS 1159977-46-4C19H18ClN3O6S
Rivaroxaban-13C6
CAS 1261392-59-9C19H18ClN3O5S
Dechloro-rivaroxaban
CAS 1415566-28-7C19H19N3O5S
![5-Chloro-N-tert-butyl-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]oxazolidin-5-yl]methyl}thiophene-2-carboxamide chemical structure, C23H26ClN3O5S, CAS 1313613-21-6](/s/NSYPTPQYVGUKLX-QGZVFWFLSA-N.svg)
5-Chloro-N-tert-butyl-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]oxazolidin-5-yl]methyl}thiophene-2-carboxamide
CAS 1313613-21-6C23H26ClN3O5S
![5-Chloro-N-[[(5S)-4-hydroxy-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide chemical structure, C19H18ClN3O6S, CAS 1161719-51-2](/s/YGGWNELFPGFWHH-FVRDMJKUSA-N.svg)
5-Chloro-N-[[(5S)-4-hydroxy-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
CAS 1161719-51-2C19H18ClN3O6S
(S)-5-Chloro-N-formyl-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide
CAS 1616563-61-1C20H18ClN3O6S
4-Chlororivaroxaban
CAS 1770812-37-7C19H17Cl2N3O5S
(R)-4,5-Dichloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide
CAS 1770812-38-8C19H17Cl2N3O5S
2-Hydroxy-3-oxo-Rivaroxaban
CAS 1160169-99-2C19H18ClN3O6S
2-Hydroxy-5-oxo-Rivaroxaban
CAS 1160169-96-9C19H18ClN3O6S
![2-Thiophenecarboxamide, 3-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]- chemical structure, C19H18ClN3O5S, CAS 1855920-54-5](/s/SEWZKMKNFZNVAD-AWEZNQCLSA-N.svg)
2-Thiophenecarboxamide, 3-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-
CAS 1855920-54-5C19H18ClN3O5S
Wxe6yaf4DH
CAS 2305917-61-5C25H28ClN3O6S
(S)-4-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide
CAS 1350288-77-5C19H18ClN3O5S