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Murcko scaffold

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide scaffold

17 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 29
Chemicals: 17
With full pages: 7

Scaffold SMILES

O=C(COc1coc(CN2CCCc3ccccc32)cc1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide page

Murcko scaffold O=C(COc1coc(CN2CCCc3ccccc32)cc1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide chemical structure, C23H22N2O4, CAS 898455-72-6

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide

CAS 898455-72-6C₂₃H₂₂N₂O₄

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(o-tolyl)acetamide chemical structure, C24H24N2O4, CAS 898416-98-3

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(o-tolyl)acetamide

CAS 898416-98-3C₂₄H₂₄N₂O₄

2-[6-(3,4-Dihydro-2H-quinolin-1-ylmethyl)-4-oxopyran-3-yl]oxy-N-(3-methylphenyl)acetamide chemical structure, C24H24N2O4, CAS 898440-65-8

2-[6-(3,4-Dihydro-2H-quinolin-1-ylmethyl)-4-oxopyran-3-yl]oxy-N-(3-methylphenyl)acetamide

CAS 898440-65-8C₂₄H₂₄N₂O₄

2-[6-(3,4-Dihydro-2H-quinolin-1-ylmethyl)-4-oxopyran-3-yl]oxy-N-(4-methylphenyl)acetamide chemical structure, C24H24N2O4, CAS 898440-70-5

2-[6-(3,4-Dihydro-2H-quinolin-1-ylmethyl)-4-oxopyran-3-yl]oxy-N-(4-methylphenyl)acetamide

CAS 898440-70-5C₂₄H₂₄N₂O₄

2-[6-(3,4-Dihydro-2H-quinolin-1-ylmethyl)-4-oxopyran-3-yl]oxy-N-(2,3-dimethylphenyl)acetamide chemical structure, C25H26N2O4, CAS 898455-99-7

2-[6-(3,4-Dihydro-2H-quinolin-1-ylmethyl)-4-oxopyran-3-yl]oxy-N-(2,3-dimethylphenyl)acetamide

CAS 898455-99-7C₂₅H₂₆N₂O₄

2-[6-(3,4-Dihydro-2H-quinolin-1-ylmethyl)-4-oxopyran-3-yl]oxy-N-(4-methoxyphenyl)acetamide chemical structure, C24H24N2O5, CAS 898417-32-8

2-[6-(3,4-Dihydro-2H-quinolin-1-ylmethyl)-4-oxopyran-3-yl]oxy-N-(4-methoxyphenyl)acetamide

CAS 898417-32-8C₂₄H₂₄N₂O₅

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(2,5-dimethoxyphenyl)acetamide chemical structure, C25H26N2O6, CAS 898440-94-3

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(2,5-dimethoxyphenyl)acetamide

CAS 898440-94-3C₂₅H₂₆N₂O₆

N-(3-Chlorophenyl)-2-({4-oxo-6-[(1,2,3,4-tetrahydroquinolin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide chemical structure, C23H21ClN2O4, CAS 898465-18-4

N-(3-Chlorophenyl)-2-({4-oxo-6-[(1,2,3,4-tetrahydroquinolin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide

CAS 898465-18-4C₂₃H₂₁ClN₂O₄

N-(3-Chloro-4-methylphenyl)-2-((6-((3,4-dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)acetamide chemical structure, C24H23ClN2O4, CAS 898439-79-7

N-(3-Chloro-4-methylphenyl)-2-((6-((3,4-dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)acetamide

CAS 898439-79-7C₂₄H₂₃ClN₂O₄

N-(5-Chloro-2-methoxyphenyl)-2-((6-((3,4-dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)acetamide chemical structure, C24H23ClN2O5, CAS 898439-81-1

N-(5-Chloro-2-methoxyphenyl)-2-((6-((3,4-dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)acetamide

CAS 898439-81-1C₂₄H₂₃ClN₂O₅

N-(4-Nitrophenyl)-2-({4-oxo-6-[(1,2,3,4-tetrahydroquinolin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide chemical structure, C23H21N3O6, CAS 898456-36-5

N-(4-Nitrophenyl)-2-({4-oxo-6-[(1,2,3,4-tetrahydroquinolin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide

CAS 898456-36-5C₂₃H₂₁N₃O₆

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(2-ethoxyphenyl)acetamide chemical structure, C25H26N2O5, CAS 898456-24-1

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(2-ethoxyphenyl)acetamide

CAS 898456-24-1C₂₅H₂₆N₂O₅

N-(4-Acetylphenyl)-2-((6-((3,4-dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)acetamide chemical structure, C25H24N2O5, CAS 898441-06-0

N-(4-Acetylphenyl)-2-((6-((3,4-dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)acetamide

CAS 898441-06-0C₂₅H₂₄N₂O₅

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(2-(trifluoromethyl)phenyl)acetamide chemical structure, C24H21F3N2O4, CAS 898465-26-4

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(2-(trifluoromethyl)phenyl)acetamide

CAS 898465-26-4C₂₄H₂₁F₃N₂O₄

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(4-(trifluoromethyl)phenyl)acetamide chemical structure, C24H21F3N2O4, CAS 898465-28-6

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(4-(trifluoromethyl)phenyl)acetamide

CAS 898465-28-6C₂₄H₂₁F₃N₂O₄

2-({4-Oxo-6-[(1,2,3,4-tetrahydroquinolin-1-yl)methyl]-4H-pyran-3-yl}oxy)-N-[4-(trifluoromethoxy)phenyl]acetamide chemical structure, C24H21F3N2O5, CAS 898465-30-0

2-({4-Oxo-6-[(1,2,3,4-tetrahydroquinolin-1-yl)methyl]-4H-pyran-3-yl}oxy)-N-[4-(trifluoromethoxy)phenyl]acetamide

CAS 898465-30-0C₂₄H₂₁F₃N₂O₅

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(3-nitrophenyl)acetamide chemical structure, C23H21N3O6, CAS 898417-44-2

2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(3-nitrophenyl)acetamide

CAS 898417-44-2C₂₃H₂₁N₃O₆