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Murcko scaffold

Phenacyl 1-quinolin-8-ylsulfonylpiperidine-4-carboxylate scaffold

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
31
Chemicals
6
With full pages
4
Scaffold SMILES

O=C(COC(=O)C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Phenacyl 1-quinolin-8-ylsulfonylpiperidine-4-carboxylate page
Murcko scaffold O=C(COC(=O)C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Phenacyl 1-quinolin-8-ylsulfonylpiperidine-4-carboxylate chemical structure, C23H22N2O5S, CAS 326889-76-3
Phenacyl 1-quinolin-8-ylsulfonylpiperidine-4-carboxylate
CAS 326889-76-3C23H22N2O5S
2-(4-Methoxyphenyl)-2-oxoethyl 1-(8-quinolinylsulfonyl)-4-piperidinecarboxylate chemical structure, C24H24N2O6S, CAS 326889-75-2
2-(4-Methoxyphenyl)-2-oxoethyl 1-(8-quinolinylsulfonyl)-4-piperidinecarboxylate
CAS 326889-75-2C24H24N2O6S
2-(4-Chlorophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate chemical structure, C23H21ClN2O5S, CAS 326889-73-0
2-(4-Chlorophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate
CAS 326889-73-0C23H21ClN2O5S
2-(4-Fluorophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate chemical structure, C23H21FN2O5S, CAS 327094-38-2
2-(4-Fluorophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate
CAS 327094-38-2C23H21FN2O5S
2-(4-Nitrophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate chemical structure, C23H21N3O7S, CAS 327093-26-5
2-(4-Nitrophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate
CAS 327093-26-5C23H21N3O7S
2-(3-Nitrophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate chemical structure, C23H21N3O7S, CAS 327093-57-2
2-(3-Nitrophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate
CAS 327093-57-2C23H21N3O7S