Murcko scaffold
Ring system with 4 rings and 18 atoms
23 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 18
- Chemicals
- 23
- With full pages
- 6
Scaffold SMILES
O=C1CCC2=C(CCC3C2CCC2CCCC23)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 23 of 23 chemicals
Infecundin
CAS 13577-86-1C20H26O2
Norethynodrel
CAS 68-23-5C20H26O2
Norgesterone
CAS 13563-60-5C20H28O2
Vestalin
CAS 8064-75-3C40H52O4
19-Nor-17-alpha-pregn-5(10)-en-20-yn-3-one
CAS 13081-50-0C20H26O
17-Hydroxy-19-nor-17alpha-pregn-5(10)-en-3-one
CAS 6318-07-6C20H30O2
Prenortestosterone
CAS 1089-78-7C18H26O2
17-(Acetyloxy)-,(17beta)-estr-5(10)-en-3-one
CAS 19906-32-2C20H28O3
3-Oxoestr-5(10)-en-17-yl propanoate
CAS 13587-78-5C21H30O3
17beta-Hydroxy-1,17-dimethylestr-5(10)-en-3-one
CAS 4712-25-8C20H30O2
Tibolone
CAS 5630-53-5C21H28O2
![17-Hydroxy-13,17-dimethyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one chemical structure, C19H28O2](/s/BTGXWXORQARJRC-UHFFFAOYSA-N.svg)
17-Hydroxy-13,17-dimethyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
C19H28O2
(17alpha)-17-Hydroxy-3-oxo-19-norpregn-5(10)-ene-21-nitrile
CAS 65928-65-6C20H27NO2
17-beta-Hydroxy-17-propylestr-5(10)-en-3-one
CAS 96059-70-0C21H32O2
Tibolone EP impurity D
CAS 32297-45-3C21H28O2
![(8R,9S,13S,14S,17S)-17-Buta-1,3-diynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one chemical structure, C22H26O2, CAS 2010-50-6](/s/CRWMSOOXZANYFV-AANPDWTMSA-N.svg)
(8R,9S,13S,14S,17S)-17-Buta-1,3-diynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
CAS 2010-50-6C22H26O2
ESTR-5(10)-EN-3-one, 17-beta-HYDROXY-17-alpha-METHYL-
CAS 2741-75-5C19H28O2
Levonorgestrel EP impurity B
CAS 19914-67-1C21H28O2
delta-5(10)-Norethindrone acetate
CAS 19637-28-6C22H28O3
![rac 8alpha-[Delta-5(10)]-Norgestrel chemical structure, C21H28O2, CAS 5541-87-7](/s/QCMLVDXPKCBMFQ-SYAJIYQZSA-N.svg)
rac 8alpha-[Delta-5(10)]-Norgestrel
CAS 5541-87-7C21H28O2
![(1S,3aS,3bS,9bS,11aS)-1-Hydroxy-11a-methyl-1,2,3,3a,3b,4,5,6,8,9,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one chemical structure, C18H26O2, CAS 2919-37-1](/s/BAZGVDKAIHZPOH-FPSMNIFISA-N.svg)
(1S,3aS,3bS,9bS,11aS)-1-Hydroxy-11a-methyl-1,2,3,3a,3b,4,5,6,8,9,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one
CAS 2919-37-1C18H26O2
![(1R,3aR,3bS,9bR,11aR)-1-Hydroxy-11a-methyl-1,2,3,3a,3b,4,5,6,8,9,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one chemical structure, C18H26O2, CAS 4019-93-6](/s/BAZGVDKAIHZPOH-QXDIGNSFSA-N.svg)
(1R,3aR,3bS,9bR,11aR)-1-Hydroxy-11a-methyl-1,2,3,3a,3b,4,5,6,8,9,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one
CAS 4019-93-6C18H26O2
(17b)-17-Hydroxy-17-methylestr-5(10)-en-3-one
C19H28O2
Related scaffolds
Same ring framework with different atoms or bond orders
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O=C1CCC2C(CCC3C4CCCC4CCC23)C153 chemicals
O=C1CCC2C1CCC1c3ccccc3CCC1239 chemicals
C1CCC2C3=C(CCC2C1)C1CCCC1CC338 chemicals
O=C1CCC2C1CCC1C3CCCCC3CCC2132 chemicals
O=C1CCC2C1CCC1C3CCCCC3=CCC2130 chemicals
O=C1C=C2CCC3C4CCC(=O)C4CCC3C2CC129 chemicals
C1=C2C3CCCC3CCC2C2CCCCC2C125 chemicals