CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 14 atoms

41 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
41
With full pages
8
Scaffold SMILES

S=c1[nH]ncn1N=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]ncn1N=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

4-[(Benzylidene)amino]-3-methyl-5-mercapto-4H-[1,2,4]triazole chemical structure, C10H10N4S, CAS 75853-95-1
4-[(Benzylidene)amino]-3-methyl-5-mercapto-4H-[1,2,4]triazole
CAS 75853-95-1C10H10N4S
3-Ethyl-4-[(E)-1-(4-fluorophenyl)ethylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C12H13FN4S, CAS 466646-85-5
3-Ethyl-4-[(E)-1-(4-fluorophenyl)ethylideneamino]-1H-1,2,4-triazole-5-thione
CAS 466646-85-5C12H13FN4S
5-Ethyl-4-{[1-(4-methylphenyl)ethylidene]amino}-4H-1,2,4-triazole-3-thiol chemical structure, C13H16N4S, CAS 466646-88-8
5-Ethyl-4-{[1-(4-methylphenyl)ethylidene]amino}-4H-1,2,4-triazole-3-thiol
CAS 466646-88-8C13H16N4S
4-{[(E)-(4-Fluorophenyl)methylidene]amino}-5-(trifluoromethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C10H6F4N4S, CAS 331452-78-9
4-{[(E)-(4-Fluorophenyl)methylidene]amino}-5-(trifluoromethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS 331452-78-9C10H6F4N4S
4-({(E)-[4-(Dimethylamino)phenyl]methylidene}amino)-5-(trifluoromethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C12H12F3N5S, CAS 110625-45-1
4-({(E)-[4-(Dimethylamino)phenyl]methylidene}amino)-5-(trifluoromethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS 110625-45-1C12H12F3N5S
4-[(4-Ethylbenzylidene)amino]-5-methyl-4H-1,2,4-triazole-3-thiol chemical structure, C12H14N4S, CAS 466645-31-8
4-[(4-Ethylbenzylidene)amino]-5-methyl-4H-1,2,4-triazole-3-thiol
CAS 466645-31-8C12H14N4S
4-[(E)-(4-tert-Butylphenyl)methylideneamino]-3-(trifluoromethyl)-1H-1,2,4-triazole-5-thione chemical structure, C14H15F3N4S, CAS 496038-04-1
4-[(E)-(4-tert-Butylphenyl)methylideneamino]-3-(trifluoromethyl)-1H-1,2,4-triazole-5-thione
CAS 496038-04-1C14H15F3N4S
Ethyl 2-[(E)-(3-methyl-5-sulfanylidene-1H-1,2,4-triazol-4-yl)iminomethyl]benzoate chemical structure, C13H14N4O2S, CAS 632290-22-3
Ethyl 2-[(E)-(3-methyl-5-sulfanylidene-1H-1,2,4-triazol-4-yl)iminomethyl]benzoate
CAS 632290-22-3C13H14N4O2S
4-{[(1E)-Phenylmethylene]amino}-4H-1,2,4-triazole-3-thiol chemical structure, C9H8N4S, CAS 40159-48-6
4-{[(1E)-Phenylmethylene]amino}-4H-1,2,4-triazole-3-thiol
CAS 40159-48-6C9H8N4S
(E)-4-((4-Fluorobenzylidene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C9H7FN4S, CAS 326012-84-4
(E)-4-((4-Fluorobenzylidene)amino)-4H-1,2,4-triazole-3-thiol
CAS 326012-84-4C9H7FN4S
4-[(E)-(3-Methoxy-4-propan-2-yloxyphenyl)methylideneamino]-3-(trifluoromethyl)-1H-1,2,4-triazole-5-thione chemical structure, C14H15F3N4O2S, CAS 691385-06-5
4-[(E)-(3-Methoxy-4-propan-2-yloxyphenyl)methylideneamino]-3-(trifluoromethyl)-1H-1,2,4-triazole-5-thione
CAS 691385-06-5C14H15F3N4O2S
4-[(E)-(2-Fluorophenyl)methylideneamino]-3-methyl-1H-1,2,4-triazole-5-thione chemical structure, C10H9FN4S, CAS 466644-97-3
4-[(E)-(2-Fluorophenyl)methylideneamino]-3-methyl-1H-1,2,4-triazole-5-thione
CAS 466644-97-3C10H9FN4S
5-Methyl-4-[(2,3,6-trichlorobenzylidene)amino]-4H-1,2,4-triazol-3-yl hydrosulfide chemical structure, C10H7Cl3N4S, CAS 466645-03-4
5-Methyl-4-[(2,3,6-trichlorobenzylidene)amino]-4H-1,2,4-triazol-3-yl hydrosulfide
CAS 466645-03-4C10H7Cl3N4S
(E)-5-Ethyl-4-((2-fluorobenzylidene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C11H11FN4S, CAS 466645-69-2
(E)-5-Ethyl-4-((2-fluorobenzylidene)amino)-4H-1,2,4-triazole-3-thiol
CAS 466645-69-2C11H11FN4S
3-Ethyl-4-({4-nitrobenzylidene}amino)-5-sulfanyl-4H-1,2,4-triazole chemical structure, C11H11N5O2S, CAS 219611-90-2
3-Ethyl-4-({4-nitrobenzylidene}amino)-5-sulfanyl-4H-1,2,4-triazole
CAS 219611-90-2C11H11N5O2S
4-[(2,6-Dichlorobenzylidene)amino]-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C9H6Cl2N4S, CAS 466656-19-9
4-[(2,6-Dichlorobenzylidene)amino]-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS 466656-19-9C9H6Cl2N4S
5-Butyl-4-{[4-(diethylamino)benzylidene]amino}-4H-1,2,4-triazol-3-yl hydrosulfide chemical structure, C17H25N5S, CAS 467244-46-8
5-Butyl-4-{[4-(diethylamino)benzylidene]amino}-4H-1,2,4-triazol-3-yl hydrosulfide
CAS 467244-46-8C17H25N5S
3-Butyl-4-[(E)-(3-methoxy-4-propan-2-yloxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C17H24N4O2S, CAS 691385-05-4
3-Butyl-4-[(E)-(3-methoxy-4-propan-2-yloxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 691385-05-4C17H24N4O2S
4-[(E)-(3-Methoxy-4-pentoxyphenyl)methylideneamino]-3-methyl-1H-1,2,4-triazole-5-thione chemical structure, C16H22N4O2S, CAS 634164-17-3
4-[(E)-(3-Methoxy-4-pentoxyphenyl)methylideneamino]-3-methyl-1H-1,2,4-triazole-5-thione
CAS 634164-17-3C16H22N4O2S
3-Ethyl-4-[(E)-(3-methoxy-4-pentoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C17H24N4O2S, CAS 691385-12-3
3-Ethyl-4-[(E)-(3-methoxy-4-pentoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 691385-12-3C17H24N4O2S
4-[(E)-(3-Methoxy-4-pentoxyphenyl)methylideneamino]-3-propyl-1H-1,2,4-triazole-5-thione chemical structure, C18H26N4O2S, CAS 691385-13-4
4-[(E)-(3-Methoxy-4-pentoxyphenyl)methylideneamino]-3-propyl-1H-1,2,4-triazole-5-thione
CAS 691385-13-4C18H26N4O2S
4-[(E)-(3-Methoxy-4-pentoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C15H20N4O2S, CAS 691385-15-6
4-[(E)-(3-Methoxy-4-pentoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 691385-15-6C15H20N4O2S
5-Butyl-4-[(E)-{[3-methoxy-4-(pentyloxy)phenyl]methylidene}amino]-4H-1,2,4-triazole-3-thiol chemical structure, C19H28N4O2S, CAS 691385-16-7
5-Butyl-4-[(E)-{[3-methoxy-4-(pentyloxy)phenyl]methylidene}amino]-4H-1,2,4-triazole-3-thiol
CAS 691385-16-7C19H28N4O2S
4-[(E)-(3-Methoxy-4-pentoxyphenyl)methylideneamino]-3-(trifluoromethyl)-1H-1,2,4-triazole-5-thione chemical structure, C16H19F3N4O2S, CAS 691385-17-8
4-[(E)-(3-Methoxy-4-pentoxyphenyl)methylideneamino]-3-(trifluoromethyl)-1H-1,2,4-triazole-5-thione
CAS 691385-17-8C16H19F3N4O2S