Murcko scaffold
3-Oxabicyclo[3.3.0]octane scaffold
21 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 8
- Chemicals
- 21
- With full pages
- 3
Scaffold SMILES
C1CC2COCC2C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 21 of 21 chemicals
![3-Oxabicyclo[3.3.0]octane chemical structure, C7H12O, CAS 5623-64-3](/s/SPZXGRZMQWESTC-UHFFFAOYSA-N.svg)
3-Oxabicyclo[3.3.0]octane
CAS 5623-64-3C7H12O
![3a-Methyl-6-(propan-2-yl)hexahydro-1H-cyclopenta[c]furan-1-ol chemical structure, C11H20O2, CAS 87746-84-7](/s/RTSABEVASCJHLA-UHFFFAOYSA-N.svg)
3a-Methyl-6-(propan-2-yl)hexahydro-1H-cyclopenta[c]furan-1-ol
CAS 87746-84-7C11H20O2
![3,3,5,5-Tetramethylhexahydro-1H-cyclopenta[c]furan-1-ol chemical structure, C11H20O2, CAS 87746-88-1](/s/UMICAFAEJJVJCY-UHFFFAOYSA-N.svg)
3,3,5,5-Tetramethylhexahydro-1H-cyclopenta[c]furan-1-ol
CAS 87746-88-1C11H20O2
![Hexahydro-1H-cyclopenta[c]furan-5-ol chemical structure, C7H12O2, CAS 2238178-46-4](/s/XNLHTIIRSQEXML-UHFFFAOYSA-N.svg)
Hexahydro-1H-cyclopenta[c]furan-5-ol
CAS 2238178-46-4C7H12O2
![1H-Cyclopenta[c]furan-5-ol, hexahydro-, (3a|A,5|A,6a|A)- chemical structure, C7H12O2, CAS 118597-93-6](/s/XNLHTIIRSQEXML-MEKDEQNOSA-N.svg)
1H-Cyclopenta[c]furan-5-ol, hexahydro-, (3a|A,5|A,6a|A)-
CAS 118597-93-6C7H12O2
![Methyl hexahydro-1H-cyclopenta[c]furan-5-carboxylate chemical structure, C9H14O3, CAS 141283-37-6](/s/JUUYMVRNJPFRCU-UHFFFAOYSA-N.svg)
Methyl hexahydro-1H-cyclopenta[c]furan-5-carboxylate
CAS 141283-37-6C9H14O3
![Hexahydro-1H-cyclopenta[c]furan-5-carboxylic acid chemical structure, C8H12O3, CAS 141283-38-7](/s/USBNQIQBWXCNPI-UHFFFAOYSA-N.svg)
Hexahydro-1H-cyclopenta[c]furan-5-carboxylic acid
CAS 141283-38-7C8H12O3
![3-Methoxy-1,1-dimethylhexahydro-1H-cyclopenta[c]furan-5-ol chemical structure, C10H18O3, CAS 112014-68-3](/s/CKPGMTKVOZUBTH-UHFFFAOYSA-N.svg)
3-Methoxy-1,1-dimethylhexahydro-1H-cyclopenta[c]furan-5-ol
CAS 112014-68-3C10H18O3
Hexahydro-1H-cyclopenta(c)furan-5-amine
CAS 1361415-15-7C7H13NO
![(3aR,6aR)-3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]furan-5-carboxylic acid chemical structure, C8H12O3, CAS 2744526-52-9](/s/USBNQIQBWXCNPI-BQBZGAKWSA-N.svg)
(3aR,6aR)-3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]furan-5-carboxylic acid
CAS 2744526-52-9C8H12O3
![(3aS,6aS)-3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]furan-5-carboxylic acid chemical structure, C8H12O3, CAS 2309433-16-5](/s/USBNQIQBWXCNPI-RNFRBKRXSA-N.svg)
(3aS,6aS)-3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]furan-5-carboxylic acid
CAS 2309433-16-5C8H12O3
rac-(1R,3aR,6aS)-hexahydro-1H-cyclopenta(c)furan-1-carboxylic acid
CAS 2307772-62-7C8H12O3
![Hexahydro-1H-cyclopenta[c]furan-1-carboxylic acid chemical structure, C8H12O3, CAS 1803562-54-0](/s/GLKJJVOXLBAMEL-UHFFFAOYSA-N.svg)
Hexahydro-1H-cyclopenta[c]furan-1-carboxylic acid
CAS 1803562-54-0C8H12O3
![N-Methylhexahydro-1H-cyclopenta[c]furan-5-amine chemical structure, C8H15NO, CAS 2098117-79-2](/s/ZHYXOVUHKYTVAH-UHFFFAOYSA-N.svg)
N-Methylhexahydro-1H-cyclopenta[c]furan-5-amine
CAS 2098117-79-2C8H15NO
![N-Ethylhexahydro-1H-cyclopenta[c]furan-5-amine chemical structure, C9H17NO, CAS 2098040-78-7](/s/SPWDGTOXFXSATC-UHFFFAOYSA-N.svg)
N-Ethylhexahydro-1H-cyclopenta[c]furan-5-amine
CAS 2098040-78-7C9H17NO
![Hexahydro-cyclopenta[c]furan-4-ol chemical structure, C7H12O2, CAS 2428375-67-9](/s/MKSDKNZKFAWHKU-UHFFFAOYSA-N.svg)
Hexahydro-cyclopenta[c]furan-4-ol
CAS 2428375-67-9C7H12O2
![2-{Hexahydro-1H-cyclopenta[c]furan-5-yl}propanoic acid chemical structure, C10H16O3, CAS 2995291-36-4](/s/MVNLUXIPXNSYFQ-UHFFFAOYSA-N.svg)
2-{Hexahydro-1H-cyclopenta[c]furan-5-yl}propanoic acid
CAS 2995291-36-4C10H16O3
![(3aR,4S,6aS)-Hexahydro-1H-cyclopenta[c]furan-4-ol chemical structure, C14H24O4, CAS 2456306-59-3](/s/JIEBBXOQCFOSMZ-JMXSADOKSA-N.svg)
(3aR,4S,6aS)-Hexahydro-1H-cyclopenta[c]furan-4-ol
CAS 2456306-59-3C14H24O4
![2-{Hexahydro-1H-cyclopenta[c]furan-5-yl}acetic acid chemical structure, C9H14O3, CAS 2955708-60-6](/s/APVXQOPVJHWRGI-UHFFFAOYSA-N.svg)
2-{Hexahydro-1H-cyclopenta[c]furan-5-yl}acetic acid
CAS 2955708-60-6C9H14O3
![rac-2-[(3aR,6aR)-hexahydro-1H-cyclopenta[c]furan-5-yl]-2-methoxyacetic acid chemical structure, C10H16O4, CAS 3026641-80-2](/s/PMQXSGSGTMMWGV-ZAZKALAHSA-N.svg)
rac-2-[(3aR,6aR)-hexahydro-1H-cyclopenta[c]furan-5-yl]-2-methoxyacetic acid
CAS 3026641-80-2C10H16O4
![Hexahydro-1H-cyclopenta[c]furan-3a-ol chemical structure, C7H12O2, CAS 2932440-11-2](/s/QRCRMDOLVIVTPY-UHFFFAOYSA-N.svg)
Hexahydro-1H-cyclopenta[c]furan-3a-ol
CAS 2932440-11-2C7H12O2
Related scaffolds
Same ring framework with different atoms or bond orders
c1cn2ccsc2n190 chemicals
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c1cc2c(s1)CCC240 chemicals
c1cn2c(n1)CCC236 chemicals
C1CC2OCCC2O129 chemicals
O=C1NC2CSCC2N129 chemicals![Scaffold c1[nH]nc2c1CCC2](/scaffold/TUVBJSPUCMUOSD-UHFFFAOYSA-N/structure.svg)
c1[nH]nc2c1CCC228 chemicals![Scaffold c1cc2sccc2[nH]1](/scaffold/DWAIOCIOSRZZHO-UHFFFAOYSA-N/structure.svg)
c1cc2sccc2[nH]125 chemicals
c1cc2sccc2s125 chemicals
C1CC2CCCN2C124 chemicals![Scaffold c1n[nH]c2c1CNC2](/scaffold/CVRWHBCQJCUBFE-UHFFFAOYSA-N/structure.svg)
c1n[nH]c2c1CNC223 chemicals