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Murcko scaffold

N-(5-(5,6,7,8-Tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide scaffold

32 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
32
With full pages
6
Scaffold SMILES

O=C(Nc1nnc(-c2ccc3c(c2)CCCC3)o1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(5-(5,6,7,8-Tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide page
Murcko scaffold O=C(Nc1nnc(-c2ccc3c(c2)CCCC3)o1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

N-[5-(5,6,7,8-Tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]-3-(trifluoromethyl)benzamide chemical structure, C20H16F3N3O2, CAS 887886-34-2
N-[5-(5,6,7,8-Tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]-3-(trifluoromethyl)benzamide
CAS 887886-34-2C20H16F3N3O2
3-Nitro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C19H16N4O4, CAS 862809-17-4
3-Nitro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 862809-17-4C19H16N4O4
Methyl 4-{[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]carbamoyl}benzoate chemical structure, C21H19N3O4, CAS 851095-84-6
Methyl 4-{[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]carbamoyl}benzoate
CAS 851095-84-6C21H19N3O4
3-Methoxy-N-(5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C20H19N3O3, CAS 887885-99-6
3-Methoxy-N-(5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 887885-99-6C20H19N3O3
3,5-Dimethoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C21H21N3O4, CAS 887886-06-8
3,5-Dimethoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 887886-06-8C21H21N3O4
3,4,5-Trimethoxy-N-(5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C22H23N3O5, CAS 862809-19-6
3,4,5-Trimethoxy-N-(5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 862809-19-6C22H23N3O5
2-Fluoro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C19H16FN3O2, CAS 887887-40-3
2-Fluoro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 887887-40-3C19H16FN3O2
3-Methyl-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C20H19N3O2, CAS 887885-55-4
3-Methyl-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 887885-55-4C20H19N3O2
3,4,5-Triethoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C25H29N3O5, CAS 851095-93-7
3,4,5-Triethoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 851095-93-7C25H29N3O5
4-Cyano-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C20H16N4O2, CAS 862809-22-1
4-Cyano-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 862809-22-1C20H16N4O2
N-(5-(5,6,7,8-Tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C19H17N3O2, CAS 851095-69-7
N-(5-(5,6,7,8-Tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 851095-69-7C19H17N3O2
3-Fluoro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C19H16FN3O2, CAS 887885-77-0
3-Fluoro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 887885-77-0C19H16FN3O2
3-Chloro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C19H16ClN3O2, CAS 887888-26-8
3-Chloro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 887888-26-8C19H16ClN3O2
4-(Dimethylsulfamoyl)-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C21H22N4O4S, CAS 862809-21-0
4-(Dimethylsulfamoyl)-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 862809-21-0C21H22N4O4S
4-[Butyl(methyl)sulfamoyl]-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C24H28N4O4S, CAS 851095-94-8
4-[Butyl(methyl)sulfamoyl]-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 851095-94-8C24H28N4O4S
4-(Dimethylamino)-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C21H22N4O2, CAS 887887-83-4
4-(Dimethylamino)-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 887887-83-4C21H22N4O2
2-Chloro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C19H16ClN3O2, CAS 862809-32-3
2-Chloro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 862809-32-3C19H16ClN3O2
4-Fluoro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C19H16FN3O2, CAS 887885-70-3
4-Fluoro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 887885-70-3C19H16FN3O2
2,6-Difluoro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C19H15F2N3O2, CAS 862809-29-8
2,6-Difluoro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 862809-29-8C19H15F2N3O2
2-Methoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C20H19N3O3, CAS 851095-89-1
2-Methoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 851095-89-1C20H19N3O3
4-Nitro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C19H16N4O4, CAS 862809-16-3
4-Nitro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 862809-16-3C19H16N4O4
2,4-Dichloro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C19H15Cl2N3O2, CAS 862809-33-4
2,4-Dichloro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 862809-33-4C19H15Cl2N3O2
4-Ethoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C21H21N3O3, CAS 887887-51-6
4-Ethoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 887887-51-6C21H21N3O3
4-(Diethylsulfamoyl)-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C23H26N4O4S, CAS 851095-70-0
4-(Diethylsulfamoyl)-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 851095-70-0C23H26N4O4S