CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 25 atoms

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
4
With full pages
1
Scaffold SMILES

c1cc(C2CCNCC2)ccc1Nc1cncc(N2CCCCC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(C2CCNCC2)ccc1Nc1cncc(N2CCCCC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

5-(Piperidin-1-yl)-3-((4-(piperidin-4-yl)phenyl)amino)pyrazine-2-carboxamide chemical structure, C21H28N6O, CAS 2759182-32-4
5-(Piperidin-1-yl)-3-((4-(piperidin-4-yl)phenyl)amino)pyrazine-2-carboxamide
CAS 2759182-32-4C21H28N6O
tert-Butyl 4-(4-((3-carbamoyl-6-(piperidin-1-yl)pyrazin-2-yl)amino)phenyl)piperidine-1-carboxylate chemical structure, C26H36N6O3, CAS 2768641-80-9
tert-Butyl 4-(4-((3-carbamoyl-6-(piperidin-1-yl)pyrazin-2-yl)amino)phenyl)piperidine-1-carboxylate
CAS 2768641-80-9C26H36N6O3
tert-Butyl 4-(4-((3-cyano-6-(piperidin-1-yl)pyrazin-2-yl)amino)phenyl)piperidine-1-carboxylate chemical structure, C26H34N6O2, CAS 2768641-79-6
tert-Butyl 4-(4-((3-cyano-6-(piperidin-1-yl)pyrazin-2-yl)amino)phenyl)piperidine-1-carboxylate
CAS 2768641-79-6C26H34N6O2
5-(Piperidin-1-yl)-3-((4-(piperidin-4-yl)phenyl)amino)pyrazine-2-carboxamide 2,2,2-trifluoroacetate chemical structure, C23H29F3N6O3, CAS 2759182-33-5
5-(Piperidin-1-yl)-3-((4-(piperidin-4-yl)phenyl)amino)pyrazine-2-carboxamide 2,2,2-trifluoroacetate
CAS 2759182-33-5C23H29F3N6O3