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Murcko scaffold

Ring system with 4 rings and 25 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
6
With full pages
2
Scaffold SMILES

C1=C(c2ccccc2)CCN(CC2CCC=C(c3ccccc3)C2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=C(c2ccccc2)CCN(CC2CCC=C(c3ccccc3)C2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

1,2,3,6-Tetrahydro-4-phenyl-1-(((1R)-3-phenyl-3-cyclohexen-1-yl)methyl)pyridine chemical structure, C24H27N, CAS 150013-70-0
1,2,3,6-Tetrahydro-4-phenyl-1-(((1R)-3-phenyl-3-cyclohexen-1-yl)methyl)pyridine
CAS 150013-70-0C24H27N
PD-147693 chemical structure, C24H27NO, CAS 163239-24-5
PD-147693
CAS 163239-24-5C24H27NO
PD-163637 chemical structure, C24H27NO4S, CAS 192505-92-3
PD-163637
CAS 192505-92-3C24H27NO4S
PD-163639 chemical structure, C24H27NO5S, CAS 192505-93-4
PD-163639
CAS 192505-93-4C24H27NO5S
1,2,3,6-Tetrahydro-4-phenyl-1-((3-phenyl-3-cyclohexen-1-yl)methyl)pyridine maleate, R- chemical structure, C28H31NO4, CAS 178555-05-0
1,2,3,6-Tetrahydro-4-phenyl-1-((3-phenyl-3-cyclohexen-1-yl)methyl)pyridine maleate, R-
CAS 178555-05-0C28H31NO4
Phenol, 4-((5R)-5-((3,6-dihydro-4-(4-hydroxyphenyl)-1(2H)-pyridinyl)methyl)-1-cyclohexen-1-yl)- chemical structure, C24H27NO2, CAS 216884-47-8
Phenol, 4-((5R)-5-((3,6-dihydro-4-(4-hydroxyphenyl)-1(2H)-pyridinyl)methyl)-1-cyclohexen-1-yl)-
CAS 216884-47-8C24H27NO2