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Murcko scaffold

Ring system with 3 rings and 17 atoms

13 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 17
Chemicals: 13
With full pages: 10

Scaffold SMILES

O=c1ccc2cccc(CN3CCCC3)c2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1ccc2cccc(CN3CCCC3)c2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

7-Hydroxy-4-propyl-8-(pyrrolidin-1-ylmethyl)chromen-2-one chemical structure, C17H21NO3, CAS 313471-35-1

7-Hydroxy-4-propyl-8-(pyrrolidin-1-ylmethyl)chromen-2-one

CAS 313471-35-1C₁₇H₂₁NO₃

6-Chloro-7-hydroxy-4-propyl-8-(pyrrolidin-1-ylmethyl)chromen-2-one chemical structure, C17H20ClNO3, CAS 842976-86-7

6-Chloro-7-hydroxy-4-propyl-8-(pyrrolidin-1-ylmethyl)chromen-2-one

CAS 842976-86-7C₁₇H₂₀ClNO₃

4-Butyl-7-hydroxy-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C18H23NO3, CAS 578749-64-1

4-Butyl-7-hydroxy-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one

CAS 578749-64-1C₁₈H₂₃NO₃

6-Chloro-4-ethyl-7-hydroxy-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C16H18ClNO3, CAS 577789-03-8

6-Chloro-4-ethyl-7-hydroxy-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one

CAS 577789-03-8C₁₆H₁₈ClNO₃

7-Hydroxy-4-methyl-8-(1-pyrrolidinylmethyl)-2H-chromen-2-one chemical structure, C15H17NO3, CAS 92646-98-5

7-Hydroxy-4-methyl-8-(1-pyrrolidinylmethyl)-2H-chromen-2-one

CAS 92646-98-5C₁₅H₁₇NO₃

6-Chloro-7-hydroxy-4-methyl-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C15H16ClNO3, CAS 307535-47-3

6-Chloro-7-hydroxy-4-methyl-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one

CAS 307535-47-3C₁₅H₁₆ClNO₃

7-Hydroxy-3,4-dimethyl-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C16H19NO3, CAS 858747-90-7

7-Hydroxy-3,4-dimethyl-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one

CAS 858747-90-7C₁₆H₁₉NO₃

Methyl [7-hydroxy-4-methyl-2-oxo-8-(pyrrolidin-1-ylmethyl)-2H-chromen-3-yl]acetate chemical structure, C18H21NO5, CAS 858759-93-0

Methyl [7-hydroxy-4-methyl-2-oxo-8-(pyrrolidin-1-ylmethyl)-2H-chromen-3-yl]acetate

CAS 858759-93-0C₁₈H₂₁NO₅

6-Chloro-3-ethyl-7-hydroxy-4-methyl-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H20ClNO3, CAS 708235-42-1

6-Chloro-3-ethyl-7-hydroxy-4-methyl-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one

CAS 708235-42-1C₁₇H₂₀ClNO₃

3-Ethyl-7-hydroxy-4-methyl-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H21NO3, CAS 842963-53-5

3-Ethyl-7-hydroxy-4-methyl-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one

CAS 842963-53-5C₁₇H₂₁NO₃

6-Chloro-7-hydroxy-3,4-dimethyl-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C16H18ClNO3, CAS 579442-31-2

6-Chloro-7-hydroxy-3,4-dimethyl-8-(pyrrolidin-1-ylmethyl)-2H-chromen-2-one

CAS 579442-31-2C₁₆H₁₈ClNO₃

6-Chloro-3-hexyl-7-hydroxy-4-methyl-8-(1-pyrrolidinylmethyl)-2H-chromen-2-one chemical structure, C21H28ClNO3, CAS 575463-57-9

6-Chloro-3-hexyl-7-hydroxy-4-methyl-8-(1-pyrrolidinylmethyl)-2H-chromen-2-one

CAS 575463-57-9C₂₁H₂₈ClNO₃

4-Butyl-6-chloro-7-hydroxy-8-(1-pyrrolidinylmethyl)-2H-chromen-2-one chemical structure, C18H22ClNO3, CAS 706770-90-3

4-Butyl-6-chloro-7-hydroxy-8-(1-pyrrolidinylmethyl)-2H-chromen-2-one

CAS 706770-90-3C₁₈H₂₂ClNO₃