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Murcko scaffold

1-(Thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinoline scaffold

30 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
30
With full pages
15
Scaffold SMILES

O=S(=O)(c1cccs1)N1CCCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinoline page
Murcko scaffold O=S(=O)(c1cccs1)N1CCCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

1-(Thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinoline chemical structure, C13H13NO2S2, CAS 329795-81-5
1-(Thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinoline
CAS 329795-81-5C13H13NO2S2
6-Methyl-1-(thiophene-2-sulfonyl)-1,2,3,4-tetrahydroquinoline chemical structure, C14H15NO2S2, CAS 497059-98-0
6-Methyl-1-(thiophene-2-sulfonyl)-1,2,3,4-tetrahydroquinoline
CAS 497059-98-0C14H15NO2S2
N-(1-(Thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)acetamide chemical structure, C15H16N2O3S2, CAS 898413-80-4
N-(1-(Thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)acetamide
CAS 898413-80-4C15H16N2O3S2
2-Ethoxy-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)acetamide chemical structure, C17H20N2O4S2, CAS 898429-90-8
2-Ethoxy-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)acetamide
CAS 898429-90-8C17H20N2O4S2
N-Propyl-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide chemical structure, C18H21N3O4S2, CAS 898430-28-9
N-Propyl-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide
CAS 898430-28-9C18H21N3O4S2
N-Prop-2-enyl-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide chemical structure, C18H19N3O4S2, CAS 898448-22-1
N-Prop-2-enyl-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide
CAS 898448-22-1C18H19N3O4S2
N-Butyl-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide chemical structure, C19H23N3O4S2, CAS 898414-08-9
N-Butyl-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide
CAS 898414-08-9C19H23N3O4S2
N-Methyl-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide chemical structure, C16H17N3O4S2, CAS 906151-17-5
N-Methyl-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide
CAS 906151-17-5C16H17N3O4S2
N-Ethyl-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide chemical structure, C17H19N3O4S2, CAS 898430-42-7
N-Ethyl-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide
CAS 898430-42-7C17H19N3O4S2
N'-Propan-2-yl-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide chemical structure, C18H21N3O4S2, CAS 898414-17-0
N'-Propan-2-yl-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide
CAS 898414-17-0C18H21N3O4S2
N-(2-Methylpropyl)-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide chemical structure, C19H23N3O4S2, CAS 898414-18-1
N-(2-Methylpropyl)-N'-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-7-yl)oxamide
CAS 898414-18-1C19H23N3O4S2
N-(1-(Thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide chemical structure, C14H16N2O4S3, CAS 942007-25-2
N-(1-(Thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide
CAS 942007-25-2C14H16N2O4S3
N-(1-Thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)ethanesulfonamide chemical structure, C15H18N2O4S3, CAS 941929-85-7
N-(1-Thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)ethanesulfonamide
CAS 941929-85-7C15H18N2O4S3
3,3-Dimethyl-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)butanamide chemical structure, C19H24N2O3S2, CAS 941882-52-6
3,3-Dimethyl-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)butanamide
CAS 941882-52-6C19H24N2O3S2
3-Methyl-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)butanamide chemical structure, C18H22N2O3S2, CAS 942006-84-0
3-Methyl-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)butanamide
CAS 942006-84-0C18H22N2O3S2
N-(1-Thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)acetamide chemical structure, C15H16N2O3S2, CAS 941971-80-8
N-(1-Thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)acetamide
CAS 941971-80-8C15H16N2O3S2
N-(1-(Thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)pivalamide chemical structure, C18H22N2O3S2, CAS 941882-58-2
N-(1-(Thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)pivalamide
CAS 941882-58-2C18H22N2O3S2
N-(1-Thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)propanamide chemical structure, C16H18N2O3S2, CAS 941929-71-1
N-(1-Thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)propanamide
CAS 941929-71-1C16H18N2O3S2
2-Methyl-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)propanamide chemical structure, C17H20N2O3S2, CAS 941971-82-0
2-Methyl-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)propanamide
CAS 941971-82-0C17H20N2O3S2
3-Chloro-2,2-dimethyl-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)propanamide chemical structure, C18H21ClN2O3S2, CAS 942006-96-4
3-Chloro-2,2-dimethyl-N-(1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinolin-6-yl)propanamide
CAS 942006-96-4C18H21ClN2O3S2
1-(2-Thienylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-amine chemical structure, C13H14N2O2S2, CAS 927996-64-3
1-(2-Thienylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-amine
CAS 927996-64-3C13H14N2O2S2
N1-(3-(dimethylamino)propyl)-N2-(1-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxalamide chemical structure, C20H26N4O4S2, CAS 898448-23-2
N1-(3-(dimethylamino)propyl)-N2-(1-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxalamide
CAS 898448-23-2C20H26N4O4S2
N-[2-(Diethylamino)ethyl]-N'-[1-(thiophene-2-sulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl]ethanediamide chemical structure, C21H28N4O4S2, CAS 898448-20-9
N-[2-(Diethylamino)ethyl]-N'-[1-(thiophene-2-sulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl]ethanediamide
CAS 898448-20-9C21H28N4O4S2
N1-isopentyl-N2-(1-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxalamide chemical structure, C20H25N3O4S2, CAS 898414-07-8
N1-isopentyl-N2-(1-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxalamide
CAS 898414-07-8C20H25N3O4S2