Murcko scaffold
Ring system with 10 rings and 38 atoms
7 chemicals on CompoundList share this ring system.
- Rings
- 10
- Scaffold atoms
- 38
- Chemicals
- 7
- With full pages
- 0
Scaffold SMILES
C=C1CNC2Cc3c([nH]c4ccccc34)C(c3ccc4[nH]c5c(c4c3)CCN3CC4CCC3C5C4)CC1C2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold C=C1CNC2Cc3c([nH]c4ccccc34)C(c3ccc4[nH]c5c(c4c3)CCN3CC4CCC3C5C4)CC1C2](/scaffold/TUDAQGWHPZYOPG-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 7 of 7 chemicals
![Methyl 17-ethyl-7-(15-ethylidene-18-methoxycarbonyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl)-6-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate chemical structure, C42H50N4O5](/s/PIUQMWWFBLVDEE-UHFFFAOYSA-N.svg)
Methyl 17-ethyl-7-(15-ethylidene-18-methoxycarbonyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl)-6-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
C42H50N4O5
N-Demethylconoduramine B640243K425
C42H50N4O5
Ibogamine-18-carboxylic acid, 12-((3alpha)-17-methoxy-17-oxovobasan-3-yl)-, methyl ester
CAS 80981-94-8C42H50N4O4
Isotabernamine
CAS 91794-13-7C40H48N4O2
Conodiparine A
CAS 213748-27-7C44H54N4O7
Gabunamine
CAS 66086-99-5C42H50N4O5
Conoduramine
CAS 2580-82-7C43H52N4O5