Murcko scaffold
Spiro[cyclohexane-1,9'(6'H)-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one, 7',8'-dihydro-2'-[[5-(1-piperazinyl)-2-pyridinyl]amino]- scaffold
9 chemicals on CompoundList share this ring system.
- Rings
- 6
- Scaffold atoms
- 32
- Chemicals
- 9
- With full pages
- 3
Scaffold SMILES
O=C1NCC2(CCCCC2)n2c1cc1cnc(Nc3ccc(N4CCNCC4)cn3)nc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 9 of 9 chemicals
Trilaciclib
CAS 1374743-00-6C24H30N8O
Lerociclib
CAS 1628256-23-4C26H34N8O
Spiro[cyclohexane-1,9'(6'H)-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one, 7',8'-dihydro-2'-[[5-(1-piperazinyl)-2-pyridinyl]amino]-
CAS 1374743-01-7C23H28N8O
Trilaciclib dihydrochloride
CAS 1977495-97-8C24H32Cl2N8O
G1T38 dihydrochloride
CAS 2097938-59-3C26H36Cl2N8O
Trilaciclib dihydrochloride dihydrate
CAS 2519335-12-5C24H36Cl2N8O3
GW9Ysg5vzq
CAS 3041137-12-3C29H38N8O3
Trilaciclib hemicitrate
CAS 2978007-27-9C54H68N16O9
Deuterated trilaciclib
CAS 3085639-93-3C24H30N8O