CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 29 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
11
With full pages
10
Scaffold SMILES

O=C(CN1C(=O)C(=C2SC(=S)NC2=O)c2ccccc21)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN1C(=O)C(=C2SC(=S)NC2=O)c2ccccc21)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2-((3Z)-3-(3-Isobutyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide chemical structure, C25H25N3O3S2, CAS 617698-35-8
2-((3Z)-3-(3-Isobutyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide
CAS 617698-35-8C25H25N3O3S2
2-((3Z)-3-(3-Isopropyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide chemical structure, C24H23N3O3S2, CAS 617698-36-9
2-((3Z)-3-(3-Isopropyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide
CAS 617698-36-9C24H23N3O3S2
2-((3Z)-3-(3-Ethyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide chemical structure, C23H21N3O3S2, CAS 618076-22-5
2-((3Z)-3-(3-Ethyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide
CAS 618076-22-5C23H21N3O3S2
(Z)-2-(3-(3-(sec-Butyl)-4-oxo-2-thioxothiazolidin-5-ylidene)-2-oxoindolin-1-yl)-N-phenethylacetamide chemical structure, C25H25N3O3S2, CAS 865593-04-0
(Z)-2-(3-(3-(sec-Butyl)-4-oxo-2-thioxothiazolidin-5-ylidene)-2-oxoindolin-1-yl)-N-phenethylacetamide
CAS 865593-04-0C25H25N3O3S2
2-((3Z)-3-(3-Hexyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide chemical structure, C27H29N3O3S2, CAS 618072-87-0
2-((3Z)-3-(3-Hexyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide
CAS 618072-87-0C27H29N3O3S2
2-{(3Z)-3-[3-(3-Ethoxypropyl)-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene]-2-oxo-2,3-dihydro-1H-indol-1-YL}-N-(2-phenylethyl)acetamide chemical structure, C26H27N3O4S2, CAS 618073-66-8
2-{(3Z)-3-[3-(3-Ethoxypropyl)-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene]-2-oxo-2,3-dihydro-1H-indol-1-YL}-N-(2-phenylethyl)acetamide
CAS 618073-66-8C26H27N3O4S2
2-((3Z)-3-(3-Octyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide chemical structure, C29H33N3O3S2, CAS 617698-34-7
2-((3Z)-3-(3-Octyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide
CAS 617698-34-7C29H33N3O3S2
2-[(3Z)-3-(3-Butyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl]-N-(2-phenylethyl)acetamide chemical structure, C25H25N3O3S2, CAS 617698-43-8
2-[(3Z)-3-(3-Butyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl]-N-(2-phenylethyl)acetamide
CAS 617698-43-8C25H25N3O3S2
2-[(3Z)-2-Oxo-3-(4-oxo-3-propyl-2-thioxo-1,3-thiazolidin-5-ylidene)-2,3-dihydro-1H-indol-1-yl]-N-(2-phenylethyl)acetamide chemical structure, C24H23N3O3S2, CAS 618076-24-7
2-[(3Z)-2-Oxo-3-(4-oxo-3-propyl-2-thioxo-1,3-thiazolidin-5-ylidene)-2,3-dihydro-1H-indol-1-yl]-N-(2-phenylethyl)acetamide
CAS 618076-24-7C24H23N3O3S2
2-[(3Z)-2-Oxo-3-(4-oxo-3-pentyl-2-thioxo-1,3-thiazolidin-5-ylidene)-2,3-dihydro-1H-indol-1-yl]-N-(2-phenylethyl)acetamide chemical structure, C26H27N3O3S2, CAS 618076-26-9
2-[(3Z)-2-Oxo-3-(4-oxo-3-pentyl-2-thioxo-1,3-thiazolidin-5-ylidene)-2,3-dihydro-1H-indol-1-yl]-N-(2-phenylethyl)acetamide
CAS 618076-26-9C26H27N3O3S2
2-((3Z)-3-(3-Methyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide chemical structure, C22H19N3O3S2, CAS 618076-28-1
2-((3Z)-3-(3-Methyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl)-N-(2-phenylethyl)acetamide
CAS 618076-28-1C22H19N3O3S2