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Murcko scaffold

Ring system with 3 rings and 18 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
5
With full pages
1
Scaffold SMILES

O=C(CN1CCCCC1)Nc1cc2c(s1)CCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN1CCCCC1)Nc1cc2c(s1)CCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Methyl 2-[[2-(4-methylpiperidin-1-yl)acetyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate chemical structure, C17H24N2O3S, CAS 315707-66-5
Methyl 2-[[2-(4-methylpiperidin-1-yl)acetyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
CAS 315707-66-5C17H24N2O3S
N-(3-Cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-2-piperidin-1-ylacetamide chemical structure, C15H19N3OS, CAS 315707-91-6
N-(3-Cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-2-piperidin-1-ylacetamide
CAS 315707-91-6C15H19N3OS
Ethyl 2-[2-(piperidin-1-yl)acetamido]-4H,5H,6H-cyclopenta[b]thiophene-3-carboxylate chemical structure, C17H24N2O3S, CAS 314245-02-8
Ethyl 2-[2-(piperidin-1-yl)acetamido]-4H,5H,6H-cyclopenta[b]thiophene-3-carboxylate
CAS 314245-02-8C17H24N2O3S
Ethyl 2-[2-(4-methylpiperidin-1-yl)acetamido]-4H,5H,6H-cyclopenta[b]thiophene-3-carboxylate chemical structure, C18H26N2O3S, CAS 317328-64-6
Ethyl 2-[2-(4-methylpiperidin-1-yl)acetamido]-4H,5H,6H-cyclopenta[b]thiophene-3-carboxylate
CAS 317328-64-6C18H26N2O3S
Methyl 2-[(2-piperidin-1-ylacetyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate chemical structure, C16H22N2O3S, CAS 891401-09-5
Methyl 2-[(2-piperidin-1-ylacetyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
CAS 891401-09-5C16H22N2O3S