Murcko scaffold
Ring system with 4 rings and 18 atoms
14 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 18
- Chemicals
- 14
- With full pages
- 6
Scaffold SMILES
O=C1C=CC23CCNC(Cc4ccccc42)C3=C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 14 of 14 chemicals
2-Methylflavinantine
CAS 23979-25-1C20H23NO4
Salutaridine, (-)-
CAS 4090-18-0C19H21NO4
Agn-PC-00evnm
CAS 7238-56-4C20H23NO4
Salutaridine
CAS 1936-18-1C19H21NO4
![(1R,9S)-4-Hydroxy-3,13-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,10,13-pentaen-12-one chemical structure, C19H21NO4, CAS 76202-24-9](/s/HXXOHXYFRUBUFP-ORAYPTAESA-N.svg)
(1R,9S)-4-Hydroxy-3,13-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,10,13-pentaen-12-one
CAS 76202-24-9C19H21NO4
Flavinantine
CAS 19777-82-3C19H21NO4
6-O-Demethylsalutaridine
CAS 27669-33-6C18H19NO4
O-Methylpallidine
CAS 27510-33-4C20H23NO4
N-Norsinoactine
CAS 13186-21-5C18H19NO4
Pallidine
CAS 25650-75-3C19H21NO4
5,6,8,14-Tetradehydro-3-hydroxy-2,6-dimethoxy-17-methylmorphinan-7-one
C19H21NO4
O4-Acetyl-O6-demethylsalutaridine
CAS 75820-93-8C20H21NO5
O,O-Diacetyl-O6-demethylsalutaridine
CAS 75820-95-0C22H23NO6
Salutaridine acetate
CAS 2611-69-0C21H23NO5
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1ccc2c([nH]1)CC1C=CCC23NCCCC13](/scaffold/VKEZNBQOJFJFFP-UHFFFAOYSA-N/structure.svg)
