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Murcko scaffold

Ring system with 3 rings and 18 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
16
With full pages
8
Scaffold SMILES

O=C(C1CC1)N1CCN=C1SCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C1CC1)N1CCN=C1SCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Cyclopropyl-[2-[(3-methylphenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C15H18N2OS, CAS 851803-13-9
Cyclopropyl-[2-[(3-methylphenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851803-13-9C15H18N2OS
Cyclopropyl(2-((4-methylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C15H18N2OS, CAS 851804-78-9
Cyclopropyl(2-((4-methylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851804-78-9C15H18N2OS
Cyclopropyl(2-((3-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C15H15F3N2OS, CAS 851805-55-5
Cyclopropyl(2-((3-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851805-55-5C15H15F3N2OS
2-[(4-Chlorobenzyl)thio]-1-(cyclopropylcarbonyl)-4,5-dihydro-1H-imidazole chemical structure, C14H15ClN2OS, CAS 851801-47-3
2-[(4-Chlorobenzyl)thio]-1-(cyclopropylcarbonyl)-4,5-dihydro-1H-imidazole
CAS 851801-47-3C14H15ClN2OS
Cyclopropyl-[2-[(2,5-dimethylphenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C16H20N2OS, CAS 851804-24-5
Cyclopropyl-[2-[(2,5-dimethylphenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851804-24-5C16H20N2OS
(2-((4-Bromobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopropyl)methanone chemical structure, C14H15BrN2OS, CAS 851800-36-7
(2-((4-Bromobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopropyl)methanone
CAS 851800-36-7C14H15BrN2OS
Cyclopropyl(2-((2-fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C14H15FN2OS, CAS 851806-65-0
Cyclopropyl(2-((2-fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851806-65-0C14H15FN2OS
(2-((3-Chlorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopropyl)methanone chemical structure, C14H15ClN2OS, CAS 851807-97-1
(2-((3-Chlorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopropyl)methanone
CAS 851807-97-1C14H15ClN2OS
Cyclopropyl-[2-[(2-methylphenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C15H18N2OS, CAS 851800-94-7
Cyclopropyl-[2-[(2-methylphenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851800-94-7C15H18N2OS
Cyclopropyl-[2-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C15H15F3N2OS, CAS 851805-95-3
Cyclopropyl-[2-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851805-95-3C15H15F3N2OS
Cyclopropyl-[2-[(4-nitrophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C14H15N3O3S, CAS 851802-07-8
Cyclopropyl-[2-[(4-nitrophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851802-07-8C14H15N3O3S
Cyclopropyl(2-((3-fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C14H15FN2OS, CAS 851864-69-2
Cyclopropyl(2-((3-fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851864-69-2C14H15FN2OS
Cyclopropyl-[2-[(4-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C14H15FN2OS, CAS 851865-49-1
Cyclopropyl-[2-[(4-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851865-49-1C14H15FN2OS
Cyclopropyl-[2-[(3-nitrophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C14H15N3O3S, CAS 851808-42-9
Cyclopropyl-[2-[(3-nitrophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851808-42-9C14H15N3O3S
(2-((2-Chlorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopropyl)methanone chemical structure, C14H15ClN2OS, CAS 851803-81-1
(2-((2-Chlorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopropyl)methanone
CAS 851803-81-1C14H15ClN2OS
(2-((2-Chloro-6-fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopropyl)methanone chemical structure, C14H14ClFN2OS, CAS 851802-66-9
(2-((2-Chloro-6-fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopropyl)methanone
CAS 851802-66-9C14H14ClFN2OS