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Murcko scaffold

Ring system with 4 rings and 27 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
11
With full pages
7
Scaffold SMILES

O=S(=O)(NCC(c1ccco1)N1CCc2ccccc2C1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(NCC(c1ccco1)N1CCc2ccccc2C1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-2,4,6-trimethylbenzenesulfonamide chemical structure, C24H28N2O3S, CAS 898458-69-0
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-2,4,6-trimethylbenzenesulfonamide
CAS 898458-69-0C24H28N2O3S
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-2-methoxy-5-methylbenzenesulfonamide chemical structure, C23H26N2O4S, CAS 898458-74-7
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-2-methoxy-5-methylbenzenesulfonamide
CAS 898458-74-7C23H26N2O4S
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-4-methoxybenzenesulfonamide chemical structure, C22H24N2O4S, CAS 898416-71-2
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-4-methoxybenzenesulfonamide
CAS 898416-71-2C22H24N2O4S
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-5-fluoro-2-methoxybenzenesulfonamide chemical structure, C22H23FN2O4S, CAS 898416-75-6
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-5-fluoro-2-methoxybenzenesulfonamide
CAS 898416-75-6C22H23FN2O4S
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-4-fluorobenzenesulfonamide chemical structure, C21H21FN2O3S, CAS 898416-67-6
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-4-fluorobenzenesulfonamide
CAS 898416-67-6C21H21FN2O3S
4-Bromo-N-(2-(3,4-dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)benzenesulfonamide chemical structure, C21H21BrN2O3S, CAS 898416-69-8
4-Bromo-N-(2-(3,4-dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)benzenesulfonamide
CAS 898416-69-8C21H21BrN2O3S
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-4-methylbenzenesulfonamide chemical structure, C22H24N2O3S, CAS 898433-22-2
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-4-methylbenzenesulfonamide
CAS 898433-22-2C22H24N2O3S
4-Chloro-N-(2-(3,4-dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)benzenesulfonamide chemical structure, C21H21ClN2O3S, CAS 898458-71-4
4-Chloro-N-(2-(3,4-dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)benzenesulfonamide
CAS 898458-71-4C21H21ClN2O3S
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-4-nitrobenzenesulfonamide chemical structure, C21H21N3O5S, CAS 898433-23-3
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-4-nitrobenzenesulfonamide
CAS 898433-23-3C21H21N3O5S
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-4-fluoro-3-methylbenzenesulfonamide chemical structure, C22H23FN2O3S, CAS 903288-14-2
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-4-fluoro-3-methylbenzenesulfonamide
CAS 903288-14-2C22H23FN2O3S
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-2,5-dimethylbenzenesulfonamide chemical structure, C23H26N2O3S, CAS 898416-73-4
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)-2,5-dimethylbenzenesulfonamide
CAS 898416-73-4C23H26N2O3S