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Murcko scaffold

2-Thiohydantoin scaffold

179 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
179
With full pages
11
Scaffold SMILES

O=C1CNC(=S)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2-Thiohydantoin page
Murcko scaffold O=C1CNC(=S)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 179 chemicals

1-Ethyl-3-methyl-2-thioxo-4-imidazolidinone chemical structure, C6H10N2OS, CAS 67990-13-0
1-Ethyl-3-methyl-2-thioxo-4-imidazolidinone
CAS 67990-13-0C6H10N2OS
Hydantoin, 1-acetyl-3,5-dimethyl-2-thio- chemical structure, C7H10N2O2S, CAS 64143-07-3
Hydantoin, 1-acetyl-3,5-dimethyl-2-thio-
CAS 64143-07-3C7H10N2O2S
1-Acetyl-2-thiohydantoin chemical structure, C5H6N2O2S, CAS 584-26-9
1-Acetyl-2-thiohydantoin
CAS 584-26-9C5H6N2O2S
Albutoin, (S)- chemical structure, C10H16N2OS, CAS 52152-25-7
Albutoin, (S)-
CAS 52152-25-7C10H16N2OS
2-Thiohydantoin chemical structure, C3H4N2OS, CAS 503-87-7
2-Thiohydantoin
CAS 503-87-7C3H4N2OS
3-(2,2-Dimethoxyethyl)-2-sulfanylideneimidazolidin-4-one chemical structure, C7H12N2O3S, CAS 477889-52-4
3-(2,2-Dimethoxyethyl)-2-sulfanylideneimidazolidin-4-one
CAS 477889-52-4C7H12N2O3S
3-Allyl-5-butyl-2-thioxo-imidazolidin-4-one chemical structure, C10H16N2OS, CAS 102880-28-4
3-Allyl-5-butyl-2-thioxo-imidazolidin-4-one
CAS 102880-28-4C10H16N2OS
5,5-Dimethyl-2-sulfanylideneimidazolidin-4-one chemical structure, C5H8N2OS, CAS 15998-93-3
5,5-Dimethyl-2-sulfanylideneimidazolidin-4-one
CAS 15998-93-3C5H8N2OS
3-Allyl-1-methyl-2-thioxoimidazolidin-4-one chemical structure, C7H10N2OS, CAS 97403-83-3
3-Allyl-1-methyl-2-thioxoimidazolidin-4-one
CAS 97403-83-3C7H10N2OS
4-Imidazolidinone, 5-(2-methylpropyl)-2-thioxo- chemical structure, C7H12N2OS, CAS 56805-19-7
4-Imidazolidinone, 5-(2-methylpropyl)-2-thioxo-
CAS 56805-19-7C7H12N2OS
3-(2-Aminoethyl)-2-thioxo-4-imidazolidinone chemical structure, C5H9N3OS, CAS 87-54-7
3-(2-Aminoethyl)-2-thioxo-4-imidazolidinone
CAS 87-54-7C5H9N3OS
5-(2-Methylpropyl)-3-(2-propen-1-yl)-2-thioxo-4-imidazolidinone chemical structure, C10H16N2OS, CAS 830-89-7
5-(2-Methylpropyl)-3-(2-propen-1-yl)-2-thioxo-4-imidazolidinone
CAS 830-89-7C10H16N2OS
3-(2-Propen-1-yl)-2-thioxo-4-imidazolidinone chemical structure, C6H8N2OS, CAS 2010-16-4
3-(2-Propen-1-yl)-2-thioxo-4-imidazolidinone
CAS 2010-16-4C6H8N2OS
5-Methyl-2-thioxo-4-imidazolidinone chemical structure, C4H6N2OS, CAS 33368-94-4
5-Methyl-2-thioxo-4-imidazolidinone
CAS 33368-94-4C4H6N2OS
4-Imidazolidinone, 3-methyl-5-(2-methylpropyl)-2-thioxo- chemical structure, C8H14N2OS, CAS 1076-72-8
4-Imidazolidinone, 3-methyl-5-(2-methylpropyl)-2-thioxo-
CAS 1076-72-8C8H14N2OS
3-Allyl-5,5-dimethyl-2-thioxoimidazolidin-4-one chemical structure, C8H12N2OS, CAS 53517-95-6
3-Allyl-5,5-dimethyl-2-thioxoimidazolidin-4-one
CAS 53517-95-6C8H12N2OS
Methylthiohydantoin chemical structure, C4H6N2OS, CAS 694-68-8
Methylthiohydantoin
CAS 694-68-8C4H6N2OS
3-(Prop-2-en-1-yl)-5-propyl-2-sulfanyl-3,5-dihydro-4H-imidazol-4-one chemical structure, C9H14N2OS, CAS 2176-92-3
3-(Prop-2-en-1-yl)-5-propyl-2-sulfanyl-3,5-dihydro-4H-imidazol-4-one
CAS 2176-92-3C9H14N2OS
4-Imidazolidinone, 5-methyl-3-(2-propenyl)-2-thioxo- chemical structure, C7H10N2OS, CAS 49630-32-2
4-Imidazolidinone, 5-methyl-3-(2-propenyl)-2-thioxo-
CAS 49630-32-2C7H10N2OS
4-Imidazolidinone, 3-ethyl-5-(2-methylpropyl)-2-thioxo- chemical structure, C9H16N2OS, CAS 51112-68-6
4-Imidazolidinone, 3-ethyl-5-(2-methylpropyl)-2-thioxo-
CAS 51112-68-6C9H16N2OS
Hydantoin, 3-(3-(dimethylamino)propyl)-5-isopropyl-2-thio- chemical structure, C11H21N3OS, CAS 86503-12-0
Hydantoin, 3-(3-(dimethylamino)propyl)-5-isopropyl-2-thio-
CAS 86503-12-0C11H21N3OS
Hydantoin, 3-(3-(dimethylamino)propyl)-5-isobutyl-2-thio- chemical structure, C12H23N3OS, CAS 86503-13-1
Hydantoin, 3-(3-(dimethylamino)propyl)-5-isobutyl-2-thio-
CAS 86503-13-1C12H23N3OS
Hydantoin, 5-sec-butyl-3-(3-(dimethylamino)propyl)-2-thio- chemical structure, C12H23N3OS, CAS 86503-14-2
Hydantoin, 5-sec-butyl-3-(3-(dimethylamino)propyl)-2-thio-
CAS 86503-14-2C12H23N3OS
Hydantoin, 3-(3-(diethylamino)propyl)-5-isopropyl-2-thio- chemical structure, C13H25N3OS, CAS 86503-22-2
Hydantoin, 3-(3-(diethylamino)propyl)-5-isopropyl-2-thio-
CAS 86503-22-2C13H25N3OS