Murcko scaffold
Ring system with 5 rings and 30 atoms
14 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 30
- Chemicals
- 14
- With full pages
- 3
Scaffold SMILES
O=C(CSc1nc2c(c(=O)n1-c1ccccc1)SCC2)Nc1nc2ccccc2s1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 14 of 14 chemicals
Iwp-2
CAS 686770-61-6C22H18N4O2S3
![N-(6-Methylbenzo[d]thiazol-2-yl)-2-((4-oxo-3-(p-tolyl)-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide chemical structure, C23H20N4O2S3, CAS 686771-50-6](/s/OHTQDSOKLDDTDP-UHFFFAOYSA-N.svg)
N-(6-Methylbenzo[d]thiazol-2-yl)-2-((4-oxo-3-(p-tolyl)-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
CAS 686771-50-6C23H20N4O2S3
![2-((3-(2-Methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide chemical structure, C23H20N4O3S3, CAS 686772-17-8](/s/RHUJMHOIQBDFQR-UHFFFAOYSA-N.svg)
2-((3-(2-Methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
CAS 686772-17-8C23H20N4O3S3
![N-(Benzo[d]thiazol-2-yl)-2-((3-(4-ethoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide chemical structure, C23H20N4O3S3, CAS 686772-47-4](/s/YXLWWUSXBJDDOT-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-2-((3-(4-ethoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
CAS 686772-47-4C23H20N4O3S3
![2-((3-(4-Ethoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide chemical structure, C24H22N4O3S3, CAS 850915-73-0](/s/KWTHIAYLZRHFPV-UHFFFAOYSA-N.svg)
2-((3-(4-Ethoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
CAS 850915-73-0C24H22N4O3S3
![2-((3-(4-Fluorophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide chemical structure, C22H17FN4O2S3, CAS 687561-60-0](/s/XVMHQSDMKWQNBK-UHFFFAOYSA-N.svg)
2-((3-(4-Fluorophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
CAS 687561-60-0C22H17FN4O2S3
![N-(1,3-Benzothiazol-2-yl)-2-[[3-(4-chlorophenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl]acetamide chemical structure, C21H15ClN4O2S3, CAS 687563-88-8](/s/WZEXEQWTRFWBML-UHFFFAOYSA-N.svg)
N-(1,3-Benzothiazol-2-yl)-2-[[3-(4-chlorophenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl]acetamide
CAS 687563-88-8C21H15ClN4O2S3
![N-(1,3-Benzothiazol-2-yl)-2-[[3-(4-bromophenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl]acetamide chemical structure, C21H15BrN4O2S3, CAS 862806-56-2](/s/AMYJAWDYVLUMTG-UHFFFAOYSA-N.svg)
N-(1,3-Benzothiazol-2-yl)-2-[[3-(4-bromophenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl]acetamide
CAS 862806-56-2C21H15BrN4O2S3
![N-(Benzo[d]thiazol-2-yl)-2-((3-(4-nitrophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide chemical structure, C21H15N5O4S3, CAS 850915-97-8](/s/TYPBXMUAQQYOOO-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-2-((3-(4-nitrophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
CAS 850915-97-8C21H15N5O4S3
![N-(Benzo[d]thiazol-2-yl)-2-((3-(4-fluorophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide chemical structure, C21H15FN4O2S3, CAS 362501-62-0](/s/FTFOXUNHEKTZNN-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-2-((3-(4-fluorophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
CAS 362501-62-0C21H15FN4O2S3
![N-(Benzo[d]thiazol-2-yl)-2-((3-(2-methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide chemical structure, C22H18N4O3S3, CAS 362501-82-4](/s/HBORREDAFXDZQS-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-2-((3-(2-methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
CAS 362501-82-4C22H18N4O3S3
![2-((3-(3-Methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide chemical structure, C23H20N4O3S3, CAS 877655-65-7](/s/CFJCHBCJAHKSKR-UHFFFAOYSA-N.svg)
2-((3-(3-Methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
CAS 877655-65-7C23H20N4O3S3
![2-((3-(3,5-Dimethylphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide chemical structure, C24H22N4O2S3, CAS 877653-88-8](/s/YLCUHXIDUJNDOI-UHFFFAOYSA-N.svg)
2-((3-(3,5-Dimethylphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
CAS 877653-88-8C24H22N4O2S3
![2-((4-Oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-(trifluoromethyl)benzo[d]thiazol-2-yl)acetamide chemical structure, C22H15F3N4O2S3, CAS 1638219-06-3](/s/KSTGTGUMVOFPSQ-UHFFFAOYSA-N.svg)
2-((4-Oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-(trifluoromethyl)benzo[d]thiazol-2-yl)acetamide
CAS 1638219-06-3C22H15F3N4O2S3