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Murcko scaffold

Ring system with 2 rings and 20 atoms

13 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
13
With full pages
3
Scaffold SMILES

O=C(CSCc1ccccc1)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSCc1ccccc1)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

N-[2-(4-Methoxyphenyl)ethyl]-2-[(4-methylbenzyl)sulfanyl]acetamide chemical structure, C19H23NO2S, CAS 428488-65-7
N-[2-(4-Methoxyphenyl)ethyl]-2-[(4-methylbenzyl)sulfanyl]acetamide
CAS 428488-65-7C19H23NO2S
2-(Benzylsulfanyl)-N-[2-(4-fluorophenyl)ethyl]acetamide chemical structure, C17H18FNOS, CAS 599160-29-9
2-(Benzylsulfanyl)-N-[2-(4-fluorophenyl)ethyl]acetamide
CAS 599160-29-9C17H18FNOS
2-[(2,6-Dichlorobenzyl)sulfanyl]-N-[2-(4-methoxyphenyl)ethyl]acetamide chemical structure, C18H19Cl2NO2S, CAS 708241-28-5
2-[(2,6-Dichlorobenzyl)sulfanyl]-N-[2-(4-methoxyphenyl)ethyl]acetamide
CAS 708241-28-5C18H19Cl2NO2S
2-Benzylsulfanyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide chemical structure, C17H20N2O3S2, CAS 599160-02-8
2-Benzylsulfanyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
CAS 599160-02-8C17H20N2O3S2
2-[(4-Methylbenzyl)thio]-N-(2-phenylethyl)acetamide chemical structure, C18H21NOS, CAS 591732-33-1
2-[(4-Methylbenzyl)thio]-N-(2-phenylethyl)acetamide
CAS 591732-33-1C18H21NOS
2-(Benzylthio)-N-(3,3,3-trifluoro-2-hydroxy-2-phenylpropyl)acetamide chemical structure, C18H18F3NO2S, CAS 1351641-11-6
2-(Benzylthio)-N-(3,3,3-trifluoro-2-hydroxy-2-phenylpropyl)acetamide
CAS 1351641-11-6C18H18F3NO2S
2-(Benzylthio)-N-(2-hydroxy-2-(4-(methylthio)phenyl)ethyl)acetamide chemical structure, C18H21NO2S2, CAS 1448027-05-1
2-(Benzylthio)-N-(2-hydroxy-2-(4-(methylthio)phenyl)ethyl)acetamide
CAS 1448027-05-1C18H21NO2S2
2-(Benzylthio)-N-(2-methoxy-2-(o-tolyl)ethyl)acetamide chemical structure, C19H23NO2S, CAS 1797722-38-3
2-(Benzylthio)-N-(2-methoxy-2-(o-tolyl)ethyl)acetamide
CAS 1797722-38-3C19H23NO2S
2-(Benzylthio)-N-(2-(3-fluorophenyl)-2-methoxyethyl)acetamide chemical structure, C18H20FNO2S, CAS 1797024-05-5
2-(Benzylthio)-N-(2-(3-fluorophenyl)-2-methoxyethyl)acetamide
CAS 1797024-05-5C18H20FNO2S
2-(Benzylthio)-N-(2-methoxy-2-(2-methoxyphenyl)ethyl)acetamide chemical structure, C19H23NO3S, CAS 1790198-03-6
2-(Benzylthio)-N-(2-methoxy-2-(2-methoxyphenyl)ethyl)acetamide
CAS 1790198-03-6C19H23NO3S
2-(Benzylthio)-N-(2-(2-chlorophenyl)-2-methoxyethyl)acetamide chemical structure, C18H20ClNO2S, CAS 1795420-08-4
2-(Benzylthio)-N-(2-(2-chlorophenyl)-2-methoxyethyl)acetamide
CAS 1795420-08-4C18H20ClNO2S
2-(Benzylthio)-N-(2-(3-chlorophenyl)-2-methoxypropyl)acetamide chemical structure, C19H22ClNO2S, CAS 1788677-46-2
2-(Benzylthio)-N-(2-(3-chlorophenyl)-2-methoxypropyl)acetamide
CAS 1788677-46-2C19H22ClNO2S
Ethyl N-[(benzylsulfanyl)acetyl]phenylalaninate chemical structure, C20H23NO3S, CAS 2899-69-6
Ethyl N-[(benzylsulfanyl)acetyl]phenylalaninate
CAS 2899-69-6C20H23NO3S