CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 14 atoms

4 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
4
With full pages
3
Scaffold SMILES

O=C1CC=CN1CCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC=CN1CCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Methyl 1-[2-(4-methoxyphenyl)ethyl]-5-methyl-2-oxo-3H-pyrrole-4-carboxylate chemical structure, C16H19NO4, CAS 428834-77-9
Methyl 1-[2-(4-methoxyphenyl)ethyl]-5-methyl-2-oxo-3H-pyrrole-4-carboxylate
CAS 428834-77-9C16H19NO4
Methyl 1-[2-(3,4-dimethoxyphenyl)ethyl]-2-methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate chemical structure, C17H21NO5, CAS 337495-67-7
Methyl 1-[2-(3,4-dimethoxyphenyl)ethyl]-2-methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate
CAS 337495-67-7C17H21NO5
Methyl 2-methyl-5-oxo-1-(2-phenylethyl)-4,5-dihydro-1H-pyrrole-3-carboxylate chemical structure, C15H17NO3, CAS 371144-81-9
Methyl 2-methyl-5-oxo-1-(2-phenylethyl)-4,5-dihydro-1H-pyrrole-3-carboxylate
CAS 371144-81-9C15H17NO3
(E)-({1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(methoxycarbonyl)-5-methyl-2-oxo-2,3-dihydro-1H-pyrrol-3-yl}methylidene)(methyl)oxidoazanium chemical structure, C19H24N2O6, CAS 478260-21-8
(E)-({1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(methoxycarbonyl)-5-methyl-2-oxo-2,3-dihydro-1H-pyrrol-3-yl}methylidene)(methyl)oxidoazanium
CAS 478260-21-8C19H24N2O6