Murcko scaffold
Ring system with 4 rings and 25 atoms
9 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 9
- With full pages
- 4
Scaffold SMILES
O=C1COc2ccc(Nc3ccnc(Nc4ccccc4)n3)nc2N1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 9 of 9 chemicals
Tamatinib
CAS 841290-80-0C22H23FN6O5
R92J5U6Mjv
CAS 901119-39-9C23H25FN6O6
Fostamatinib
CAS 901119-35-5C23H26FN6O9P
R406 Benzenesulfonate
CAS 841290-81-1C28H29FN6O8S
Fostamatinib disodium
CAS 914295-16-2C23H36FN6Na2O15P
Di-tert-butyl ((6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl) phosphate
CAS 901119-38-8C31H42FN6O9P
JR1Idx058G
CAS 1294007-59-2C21H21FN6O5
p-De(methoxy)-m,m-demethyl-tamatinib
CAS 1293999-51-5C19H17FN6O4
O-Sulfo R-529
CAS 1293999-48-0C21H21FN6O8S