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Murcko scaffold

Ring system with 4 rings and 24 atoms

40 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 24
Chemicals: 40
With full pages: 7

Scaffold SMILES

O=c1ccnc2n1C(c1ccccc1)N=C(Nc1ccccc1)N2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1ccnc2n1C(c1ccccc1)N=C(Nc1ccccc1)N2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

4-(4-Methoxyphenyl)-8-methyl-2-[(4-methylphenyl)amino]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C21H21N5O2, CAS 774563-03-0

4-(4-Methoxyphenyl)-8-methyl-2-[(4-methylphenyl)amino]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 774563-03-0C₂₁H₂₁N₅O₂

8-Methyl-2-[(4-methylphenyl)amino]-4-phenyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C20H19N5O, CAS 774562-99-1

8-Methyl-2-[(4-methylphenyl)amino]-4-phenyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 774562-99-1C₂₀H₁₉N₅O

8-Methyl-4-(4-methylphenyl)-2-[(4-methylphenyl)amino]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C21H21N5O, CAS 774563-00-7

8-Methyl-4-(4-methylphenyl)-2-[(4-methylphenyl)amino]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 774563-00-7C₂₁H₂₁N₅O

2-[(4-Methoxyphenyl)amino]-8-methyl-4-phenyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C20H19N5O2, CAS 876667-44-6

2-[(4-Methoxyphenyl)amino]-8-methyl-4-phenyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 876667-44-6C₂₀H₁₉N₅O₂

2-[(2,4-Dimethylphenyl)amino]-4-(4-isopropylphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C24H27N5O, CAS 775291-72-0

2-[(2,4-Dimethylphenyl)amino]-4-(4-isopropylphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 775291-72-0C₂₄H₂₇N₅O

2-[(2,3-Dichlorophenyl)amino]-8-methyl-4-(4-methylphenyl)-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C20H17Cl2N5O, CAS 777872-78-3

2-[(2,3-Dichlorophenyl)amino]-8-methyl-4-(4-methylphenyl)-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 777872-78-3C₂₀H₁₇Cl₂N₅O

2-[(2,3-Dichlorophenyl)amino]-8-methyl-4-phenyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C19H15Cl2N5O, CAS 775291-85-5

2-[(2,3-Dichlorophenyl)amino]-8-methyl-4-phenyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 775291-85-5C₁₉H₁₅Cl₂N₅O

2-[(2,3-Dimethylphenyl)amino]-8-methyl-4-(4-methylphenyl)-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C22H23N5O, CAS 777867-91-1

2-[(2,3-Dimethylphenyl)amino]-8-methyl-4-(4-methylphenyl)-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 777867-91-1C₂₂H₂₃N₅O

4-(4-Fluorophenyl)-8-methyl-2-[(4-methylphenyl)amino]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C20H18FN5O, CAS 775291-66-2

4-(4-Fluorophenyl)-8-methyl-2-[(4-methylphenyl)amino]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 775291-66-2C₂₀H₁₈FN₅O

2-[(2,3-Dichlorophenyl)amino]-8-methyl-4-[4-(propan-2-yl)phenyl]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C22H21Cl2N5O, CAS 775291-84-4

2-[(2,3-Dichlorophenyl)amino]-8-methyl-4-[4-(propan-2-yl)phenyl]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 775291-84-4C₂₂H₂₁Cl₂N₅O

2-[(2,3-Dimethylphenyl)amino]-4-(4-ethylphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C23H25N5O, CAS 777872-74-9

2-[(2,3-Dimethylphenyl)amino]-4-(4-ethylphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 777872-74-9C₂₃H₂₅N₅O

4-(3-Chlorophenyl)-2-[(2,3-dimethylphenyl)amino]-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C21H20ClN5O, CAS 777867-96-6

4-(3-Chlorophenyl)-2-[(2,3-dimethylphenyl)amino]-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 777867-96-6C₂₁H₂₀ClN₅O

4-(2-Methoxyphenyl)-8-methyl-2-[(4-methylphenyl)amino]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C21H21N5O2, CAS 775291-67-3

4-(2-Methoxyphenyl)-8-methyl-2-[(4-methylphenyl)amino]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 775291-67-3C₂₁H₂₁N₅O₂

2-[(2,3-Dimethylphenyl)amino]-4-(4-ethoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C23H25N5O2, CAS 777867-94-4

2-[(2,3-Dimethylphenyl)amino]-4-(4-ethoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 777867-94-4C₂₃H₂₅N₅O₂

2-[(2,4-Dimethylphenyl)amino]-8-methyl-4-phenyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C21H21N5O, CAS 775291-71-9

2-[(2,4-Dimethylphenyl)amino]-8-methyl-4-phenyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 775291-71-9C₂₁H₂₁N₅O

2-[(2,3-Dichlorophenyl)amino]-4-(2-methoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C20H17Cl2N5O2, CAS 777866-95-2

2-[(2,3-Dichlorophenyl)amino]-4-(2-methoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 777866-95-2C₂₀H₁₇Cl₂N₅O₂

4-(3-Methoxyphenyl)-8-methyl-2-(4-toluidino)-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C21H21N5O2, CAS 775291-69-5

4-(3-Methoxyphenyl)-8-methyl-2-(4-toluidino)-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 775291-69-5C₂₁H₂₁N₅O₂

4-(4-Chlorophenyl)-8-methyl-2-[(4-methylphenyl)amino]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C20H18ClN5O, CAS 774563-01-8

4-(4-Chlorophenyl)-8-methyl-2-[(4-methylphenyl)amino]-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 774563-01-8C₂₀H₁₈ClN₅O

2-[(2,4-Dimethylphenyl)amino]-4-(2-methoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C22H23N5O2, CAS 775291-70-8

2-[(2,4-Dimethylphenyl)amino]-4-(2-methoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 775291-70-8C₂₂H₂₃N₅O₂

2-[(2,4-Dimethylphenyl)amino]-4-(3-methoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C22H23N5O2, CAS 775291-75-3

2-[(2,4-Dimethylphenyl)amino]-4-(3-methoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 775291-75-3C₂₂H₂₃N₅O₂

2-(4-Methoxyanilino)-4-(4-methoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C21H21N5O3, CAS 876667-43-5

2-(4-Methoxyanilino)-4-(4-methoxyphenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 876667-43-5C₂₁H₂₁N₅O₃

4-(4-Chlorophenyl)-2-(4-methoxyanilino)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C20H18ClN5O2, CAS 879621-89-3

4-(4-Chlorophenyl)-2-(4-methoxyanilino)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 879621-89-3C₂₀H₁₈ClN₅O₂

2-[(2,3-Dimethylphenyl)amino]-4-(4-fluorophenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C21H20FN5O, CAS 777867-93-3

2-[(2,3-Dimethylphenyl)amino]-4-(4-fluorophenyl)-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 777867-93-3C₂₁H₂₀FN₅O

4-(3-Bromophenyl)-2-[(4-methoxyphenyl)amino]-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one chemical structure, C20H18BrN5O2, CAS 879621-91-7

4-(3-Bromophenyl)-2-[(4-methoxyphenyl)amino]-8-methyl-1,4-dihydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one

CAS 879621-91-7C₂₀H₁₈BrN₅O₂