Murcko scaffold
Ring system with 4 rings and 36 atoms
8 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 36
- Chemicals
- 8
- With full pages
- 1
Scaffold SMILES
O=C(CNC(=O)C(Cc1ccccc1)NC(=O)CCC1C=NC=N1)NCCc1c[nH]c2ccccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=C(CNC(=O)C(Cc1ccccc1)NC(=O)CCC1C=NC=N1)NCCc1c[nH]c2ccccc12](/scaffold/UNCHEPWUVUYEAQ-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 8 of 8 chemicals
Lysyl-histidyl-phenylalanyl-arginyl-tryptophyl-glycinamide
CAS 124051-38-3C40H56N14O6
HP 228
CAS 109022-88-0C45H63N15O8
Acth (5-10)
CAS 4086-29-7C39H50N12O9
ACTH (4-10), Phe(7)-
CAS 39877-09-3C44H59N13O10S
Acth (4-11)
CAS 67224-41-3C50H71N15O11S
alpha-Msh (4-11)NH2, Ac-nle(4)-orn(5)-glu(8)-
CAS 116375-28-1C52H72N14O10
MSH (5-10), cyclic
CAS 137668-62-3C42H56N14O7
alpha-Msh(4-11)NH2, Ac-Nl4(4)-orn(5)-phe(7)-glu(8)-
CAS 116375-29-2C52H72N14O10
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C(CNC(=O)C(Cc1ccccc1)NC(=O)CCc1cnc[nH]1)NCCc1c[nH]c2ccccc12](/scaffold/QGUDJDZONCLKRC-UHFFFAOYSA-N/structure.svg)