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Murcko scaffold

Ring system with 5 rings and 23 atoms

18 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
23
Chemicals
18
With full pages
5
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCC2CC21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCC2CC21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

(1S,3S,5S,6S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-(trifluoromethyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid chemical structure, C22H18F3NO4, CAS 2380779-17-7
(1S,3S,5S,6S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-(trifluoromethyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
CAS 2380779-17-7C22H18F3NO4
(1S,5R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-1-carboxylic acid chemical structure, C21H19NO4, CAS 1932320-54-1
(1S,5R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS 1932320-54-1C21H19NO4
(1R,3S,5R)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid chemical structure, C21H19NO4, CAS 1983904-18-2
(1R,3S,5R)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
CAS 1983904-18-2C21H19NO4
(1S,3S,5S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-3-carboxylic acid chemical structure, C21H19NO4, CAS 1932109-93-7
(1S,3S,5S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
CAS 1932109-93-7C21H19NO4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-1-carboxylic acid chemical structure, C21H19NO4, CAS 1936574-25-2
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS 1936574-25-2C21H19NO4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-4-carboxylic acid chemical structure, C21H19NO4, CAS 2137787-86-9
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-4-carboxylic acid
CAS 2137787-86-9C21H19NO4
(1R,5R,6R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-6-carboxylic acid chemical structure, C21H19NO4, CAS 2137135-44-3
(1R,5R,6R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-6-carboxylic acid
CAS 2137135-44-3C21H19NO4
rac-(1R,5R)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-5-carboxylic acid chemical structure, C21H19NO4, CAS 2219376-27-7
rac-(1R,5R)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-5-carboxylic acid
CAS 2219376-27-7C21H19NO4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-6-carboxylic acid chemical structure, C21H19NO4, CAS 2137684-69-4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-6-carboxylic acid
CAS 2137684-69-4C21H19NO4
(1S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-1-carboxylic acid chemical structure, C21H19NO4, CAS 2137426-59-4
(1S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS 2137426-59-4C21H19NO4
(1R,3R,5R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-3-carboxylic acid chemical structure, C21H19NO4, CAS 2219354-07-9
(1R,3R,5R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
CAS 2219354-07-9C21H19NO4
(1R,3S,5S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-difluoro-2-azabicyclo[3.1.0]hexane-3-carboxylic acid chemical structure, C21H17F2NO4, CAS 2381562-68-9
(1R,3S,5S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-difluoro-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
CAS 2381562-68-9C21H17F2NO4
(1R,5S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-1-carboxylic acid chemical structure, C21H19NO4, CAS 2869870-20-0
(1R,5S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS 2869870-20-0C21H19NO4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-difluoro-2-azabicyclo[3.1.0]hexane-1-carboxylic acid chemical structure, C21H17F2NO4, CAS 2870673-54-2
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-difluoro-2-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS 2870673-54-2C21H17F2NO4
(1R,3S,5R,6R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-(trifluoromethyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid chemical structure, C22H18F3NO4, CAS 1060742-27-9
(1R,3S,5R,6R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-(trifluoromethyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
CAS 1060742-27-9C22H18F3NO4
(1S,3S,5R)-2-(9H-Fluoren-9-ylmethoxycarbonyl)-6,6-difluoro-2-azabicyclo[3.1.0]hexane-3-carboxylic acid chemical structure, C21H17F2NO4, CAS 2382599-69-9
(1S,3S,5R)-2-(9H-Fluoren-9-ylmethoxycarbonyl)-6,6-difluoro-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
CAS 2382599-69-9C21H17F2NO4
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexan-1-yl)acetic acid chemical structure, C22H21NO4, CAS 2923844-83-9
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[3.1.0]hexan-1-yl)acetic acid
CAS 2923844-83-9C22H21NO4
2-[2-(9H-Fluoren-9-ylmethoxycarbonyl)-2-azabicyclo[3.1.0]hexan-4-yl]acetic acid chemical structure, C22H21NO4, CAS 3022947-75-4
2-[2-(9H-Fluoren-9-ylmethoxycarbonyl)-2-azabicyclo[3.1.0]hexan-4-yl]acetic acid
CAS 3022947-75-4C22H21NO4